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Start Over Area of Honors Biochemistry and Molecular Biology

41. Production and Characterization of Class C Radical Sam Methylases Nosn and Blmorf8

open_access
Open Access
Author:
Gadsby, Lauren Kathryn
Title:
Production and Characterization of Class C Radical Sam Methylases Nosn and Blmorf8
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
SAM
iron-sulfur cluster
radical chemistry
methylase
NosN
BlmOrf8
nosiheptide
bleomycin
S-adenosyl-methionine
File:
Download Thesis_final_edits.pdf
Thesis Supervisors:
Squire J Booker, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

43. Expression and Purification of the HBO1/JADE1 Histone Acetyltransferase Complex

open_access
Open Access
Author:
Tollemar, Viktor Clifford
Title:
Expression and Purification of the HBO1/JADE1 Histone Acetyltransferase Complex
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
protein
expression
complex
hbo1
jade1
biochemistry
molecular biology
nucleosome
File:
Download Expression_and_Purification_of_the_HBO1-JADE1_Histone_Acetyltransferase_Complex.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

45. Purification and Characterization of Human Leucine-Rich Pentatricopeptide Repeat Containing Protein (LRPPRC) Expressed in Escherichia Coli

open_access
Open Access
Author:
Gilmore, Andrew Charles
Title:
Purification and Characterization of Human Leucine-Rich Pentatricopeptide Repeat Containing Protein (LRPPRC) Expressed in Escherichia Coli
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
LRPPRC
Protein
Purification
French Canadian Leigh Syndrome
Escherichia Coli
Mitochondria
File:
Download Gilmore_Purification_and_Characterizaiton_of_LRPPRC_in_E._Coli.pdf
Thesis Supervisors:
Craig Eugene Cameron, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

47. Effects of Cellulose Synthase (cesa) Mutations on Catalytic Activity, Cell Wall Structure, and Isoform Expression Profile

open_access
Open Access
Author:
Russo, Daniel Alexander
Title:
Effects of Cellulose Synthase (cesa) Mutations on Catalytic Activity, Cell Wall Structure, and Isoform Expression Profile
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Site-directed Mutagenesis
Cellulose synthase
CesA
Cellulose
Molecular Biology
GUS
Gene Expression
File:
Download Russo_Daniel_Effectsofcellulosesynthase.pdf
Thesis Supervisors:
Ming Tien, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

49. Cloning of Insecticidal BT Genes for Application to Protection of Mushrooms from Fungus Gnats

open_access
Open Access
Author:
Curtis, Matthew Steven
Title:
Cloning of Insecticidal BT Genes for Application to Protection of Mushrooms from Fungus Gnats
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Bacillus thuringiensis
BT
Molecular Cloning
Agaricus bisporus
Mushrooms
Biocontrol
File:
Download Thesis_Matthew_Curtis_BMB.pdf
Thesis Supervisors:
Ming Tien, Thesis Honors Advisor
Dr. Wayne Roger Curtis, Thesis Supervisor
David Scott Gilmour, Faculty Reader
Scott Brian Selleck, Faculty Reader

50. Improving the Diagnosis, Treatment, and Prevention of Whooping Cough: A Characterization of the Currently Circulating Strains of Bordetella Pertussis in the United States

open_access
Open Access
Author:
Meyer, Jessica A
Title:
Improving the Diagnosis, Treatment, and Prevention of Whooping Cough: A Characterization of the Currently Circulating Strains of Bordetella Pertussis in the United States
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
pertussis
bordetella
whooping
cough
vaccine
acellular
antibiotic
healthcare
File:
Download Jessica_A._Meyer_Honors_Thesis__Characterization_of_Bordetella_pertussis_.pdf
Thesis Supervisors:
Eric Thomas Harvill, Thesis Supervisor
Chen Pei David Tu, Thesis Honors Advisor
Richard John Frisque, Faculty Reader

51. The Role of Peroxisome Proliferator-Activated Receptor-b/d (PPARb/d) in Transforming Growth Factor b-Induced Epithelial-Mesenchymal Transition (EMT) of Human Lung Adenocarcinoma Cell Line

open_access
Open Access
Author:
Ali, Ayesha S
Title:
The Role of Peroxisome Proliferator-Activated Receptor-b/d (PPARb/d) in Transforming Growth Factor b-Induced Epithelial-Mesenchymal Transition (EMT) of Human Lung Adenocarcinoma Cell Line
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
cancer
human lung adenocarcinoma
lung
ppar-b/d
tgf-b
File:
Download Thesis_Draft_9.pdf
Thesis Supervisors:
Jeffrey Maurice Peters, Thesis Supervisor
Dr. Sarah Ellen Ades, Thesis Honors Advisor
Richard John Frisque, Faculty Reader

53. An Investigation of the Chemotactic Role of Osteoclasts in Breast Cancer Metastasis in Bone

open_access
Open Access
Author:
Pursnani, Richa
Title:
An Investigation of the Chemotactic Role of Osteoclasts in Breast Cancer Metastasis in Bone
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
breast cancer
metastasis
osteoclasts
osteoblasts
chemoattraction
bone
File:
Download PURSNANI_HONORS_THESIS_2014_-_An_Investigation_of_the_Chemotactic_Role_of.pdf
Thesis Supervisors:
Andrea Marie Mastro, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor
Daniel J Cosgrove, Thesis Honors Advisor
Richard John Frisque, Faculty Reader

54. A Genetic and Biochemical Analysis of the Role of the Ccr4-not Complex in Transcription Elongation and Recovery from DNA Damage in Budding Yeast

open_access
Open Access
Author:
Libert, Diane Marie
Title:
A Genetic and Biochemical Analysis of the Role of the Ccr4-not Complex in Transcription Elongation and Recovery from DNA Damage in Budding Yeast
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
RNA Polymerase II
Transcription Elongation
Transcription-coupled repair
Ccr4-Not
Not4
E3 Ubiquitin Ligase
RING domain
File:
Download Diane_Libert_honors_thesis_PSU_May_2014.pdf
Thesis Supervisors:
Joseph C. Reese, Thesis Supervisor
Chen Pei David Tu, Thesis Honors Advisor
Richard John Frisque, Faculty Reader

55. Identification and Analysis of Dnaj-2 (cg10565) as a Regulator of Synapse Development in the Drosophila Larval Neuromuscular Junction

open_access
Open Access
Author:
Lee, Joyce
Title:
Identification and Analysis of Dnaj-2 (cg10565) as a Regulator of Synapse Development in the Drosophila Larval Neuromuscular Junction
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Drosophila
Neuroscience
Genetics
File:
Download Lee_Joyce-Honors_Thesis_2014.pdf
Thesis Supervisors:
Scott Brian Selleck, Thesis Supervisor
Ming Tien, Thesis Honors Advisor

56. Impact Of Osteoblast-derived Bone Remodeling Cytokines On metastatic Breast Cancer Cell Dormancy

open_access
Open Access
Author:
Rutan, Emily Claire
Title:
Impact Of Osteoblast-derived Bone Remodeling Cytokines On metastatic Breast Cancer Cell Dormancy
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
breast cancer
bone remodeling
cytokines
cancer
dormancy
metastasis
metastases
IL-6
IL-1beta
TNF-alpha
osteoblasts
File:
Download 1-ECR_Thesis_Submit2.pdf
Thesis Supervisors:
Andrea Marie Mastro, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Richard John Frisque, Faculty Reader

58. Assessment of Nucleosomal Binding using a High-throughput Interactions by Fluorescent Intensity Assay

open_access
Open Access
Author:
Cognetti, Daniel Joseph
Title:
Assessment of Nucleosomal Binding using a High-throughput Interactions by Fluorescent Intensity Assay
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Gene regulation
Epigenetic
Chromatin
Nucleosome
HI-FI
RCC1
Ran
Histone
Biochemistry
File:
Download Cognetti_Daniel_Assessment.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

59. An examination of behaviors in Drosophila Melanogaster for their utility in an Rnai screen of autism candidate genes

open_access
Open Access
Author:
Saxena, Ritu Shalini
Title:
An examination of behaviors in Drosophila Melanogaster for their utility in an Rnai screen of autism candidate genes
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Autism
Drosophila
Melanogaster
RNAi
screen
gene candidates
behavior
assays
circadian rhythm
geotaxis
social space
File:
Download Ritu_Saxena_BMB_THESIS.pdf
Thesis Supervisors:
Scott Brian Selleck, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

60. The Role of the Rcs Phosphorelay in the Development of Antibiotic Resistance

open_access
Open Access
Author:
Gao, Geoffrey Siyuan
Title:
The Role of the Rcs Phosphorelay in the Development of Antibiotic Resistance
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Rcs phosphorelay
Antibiotic Resistance
Cell Envelope Stress Response
rcsB
rcsA
Beta-lactam antibiotics
Cefsulodin
File:
Download Geoffrey_Gao_Thesis_Final.pdf
Thesis Supervisors:
Dr. Sarah Ellen Ades, Thesis Supervisor
Ming Tien, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader