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Author:: Hoenisch, Rachel
Title:: Differentiation of iPSC-Derived Beta Cells via the Use of Modified mRNA
Area of Honors:: Biomedical Engineering
Keywords:: stem cells
iPSCs
modRNA
induced pluripotent stem cells
pancreatic beta cells
type 1 diabetes
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Thesis Supervisors:: Xiaojun Lance Lian, Thesis Supervisor
Nanyin Zhang, Thesis Honors Advisor

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Author:: Yang, Zeyu
Title:: Investigation of Dual-Switch Combination Therapy’s Efficacy in Drug Resistant Cancer Cells
Area of Honors:: Biomedical Engineering
Keywords:: Drug resistance
Suicide gene therapy
Combination therapy
NSCLC
EGFR
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Thesis Supervisors:: Justin R Pritchard, Thesis Supervisor
Jian Yang, Thesis Honors Advisor

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Author:: Selinsky, Peter
Title:: A Flow Study of the Effects of Outlet Valve Angle in the Right Side of the 12cc Penn State Pediatric Total Artificial Heart
Area of Honors:: Biomedical Engineering
Keywords:: Penn State
Particle image velocimetry (PIV)
pediatric ventricular assist device (PVAD)
total artificial heart (TAH)
ventricular assist device (VAD)
pediatric total artificial heart (pTAH)
right side of pediatric total artificial heart (RpTAH)
fluid dynamics
blood analog
mechanical circulatory support device (MCSD)
outlet valve angle
3D flow
rotational flow
wall washing
fluid velocity
flow loop
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Thesis Supervisors:: Keefe B Manning, Thesis Supervisor
Nanyin Zhang, Thesis Honors Advisor
William Joseph Weiss, Faculty Reader

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Author:: Cush, Coleman
Title:: Model Development and Analysis of the Rat Supraspinatus Muscle-Tendon-Bone Unit
Area of Honors:: Biomedical Engineering
Keywords:: finite element model
shoulder tear
sensitivity analysis
tendinopathy treatments
dry needling
focused ultrasound
rat
supraspinatus muscle-tendon-bone unit
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Thesis Supervisors:: Meghan Vidt, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Julianna Simon, Faculty Reader

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Author:: Klunk, Danielle
Title:: Development of a Prototype Gel-Based Lung System
Area of Honors:: Biomedical Engineering
Keywords:: bioprinting
lung on a chip
microfluidic device
tissue engineering
cell culture
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Thesis Supervisors:: Ibrahim Tarik Ozbolat, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor
Daniel J Hayes, Faculty Reader

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Author:: Demalis, Emily
Title:: Assessing the Influence of Biomechanical Factors in Injury Exposure for American Sign Language (ASL) Users
Area of Honors:: Biomedical Engineering
Keywords:: American Sign Language
Motion capture
Biomechanical assessments
Ballistic signing
Work envelope
Hand and wrist deviations
Factor analysis
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Thesis Supervisors:: Meghan Vidt, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Justin Lee Brown, Faculty Reader

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Author:: Rudolph, Helena
Title:: Multimodal Imaging Phantom Development for Ultrasound and Photoacoustic Imaging
Area of Honors:: Biomedical Engineering
Keywords:: Multimodal imaging
photoacoustic
ultrasound
phantom
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Thesis Supervisors:: Sri-Rajasekhar Kothapalli, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Scott H Medina, Faculty Reader

Restricted (Penn State Only)

Author:: Raich, Emma
Title:: A Study of the Effect of an Elevated Beat Rate in the Left Side of the 12cc Penn State Pediatric Total Artificial Heart
Area of Honors:: Biomedical Engineering
Keywords:: total artificial heart
pediatric
mechanical circulatory support devices
particle image velocimetry
thrombosis
elevated beat rate
wall shear rate
cardiovascular fluid dynamics
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Thesis Supervisors:: Keefe B Manning, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor
William Joseph Weiss, Faculty Reader

Open Access

Author:: Khan, Yahya
Title:: The Role of Mouse and Human Peroxisome Proliferator-Activated Receptor- α in Modulating the Hepatic Effects of Perflourohexane Sulfonate (PFHxS) in Mice
Area of Honors:: Biomedical Engineering
Keywords:: Nuclear Receptors
Species differences
Perfluorohexanesulfonic acid
Peroxisome proliferator-activated receptor alpha
Constitutive androstane receptor
Pregnane X receptor
File:: Download Final_Honors_Thesis.pdf
Thesis Supervisors:: Jeffrey Maurice Peters, Thesis Supervisor
Meghan Vidt, Thesis Honors Advisor

Restricted (Penn State Only)

Author:: Kedzierski, Alexander
Title:: Porous microgels for fabricating granular hydrogel scaffolds with hierarchical porosity to improve cell invasion
Area of Honors:: Biomedical Engineering
Keywords:: Keywords: cell infiltration
porous scaffolds
microgels
biomaterials
phase separation
Cell infiltration
Porous scaffolds
Microgels
Biomaterials
Phase Separation
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Thesis Supervisors:: Amir Sheikhi, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor

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