201. Clinically Irrelevant Concentrations of Kinase Inhibitors Contribute to Failure of Drug Repurposing Efforts in Clinical Trials: a Meta-Analysis Open Access Author: Shah, Anushka Title: Clinically Irrelevant Concentrations of Kinase Inhibitors Contribute to Failure of Drug Repurposing Efforts in Clinical Trials: a Meta-Analysis Area of Honors: Biology Keywords: clinical trialsrepurposingcancerkinase inhibitorsmeta-analysisbiologyin vitrodrug concentrations File: Download Shah_SHCThesis.pdf Thesis Supervisors: Justin R Pritchard, Thesis SupervisorRichard W Ordway, Thesis Honors Advisor
202. Investigation of Striatal Astrocytes to GABAergic Neuron Conversion In Vivo in Huntington’s Disease Mouse Model Open Access Author: Xu, Kevin Title: Investigation of Striatal Astrocytes to GABAergic Neuron Conversion In Vivo in Huntington’s Disease Mouse Model Area of Honors: Biology Keywords: ND1Dlx2Huntington's DiseaseHDGABAergic neuronstranscription factorsgene therapystriatal astrocytesR6/2 mouse modelastrocyte-to-neuron conversionND1Dlx2Huntington's DiseaseHDGABAergic neuronstranscription factorsgene therapystriatal astrocytesR6/2 mouse modelastrocyte-to-neuron conversion File: Download Xu_Kevin_Investigation_of_Striatal_Astrocytes_to_GABAergic_Neuron_Conversion_In_Vivo_in_Huntington_s_Disease_Mouse_Model.pdf Thesis Supervisors: Aimin Liu, Thesis SupervisorBernhard Luscher, Thesis Honors Advisor
203. Analyzing the evolution of the vaccine development process after the H1N1 Swine Flu Pandemic of 2009 to understand the process used to develop the COVID-19 vaccine Open Access Author: Dahal, Sabina Title: Analyzing the evolution of the vaccine development process after the H1N1 Swine Flu Pandemic of 2009 to understand the process used to develop the COVID-19 vaccine Area of Honors: Biology Keywords: COVID-19H1N1 Swine Flu of 2009InfluenzaVaccineVaccine Development ProcessPandemicmRNA vaccineEvolution of Vaccine File: Download SabinaDahal_FinalThesis.pdf Thesis Supervisors: Nik Tsotakos, Thesis SupervisorSairam V Rudrabhatla, Thesis Honors Advisor
204. Effects of sublethal neonicotinoid exposure on bumble bee (Bombus impatiens) foraging behavior Open Access Author: Moak, Ashley Title: Effects of sublethal neonicotinoid exposure on bumble bee (Bombus impatiens) foraging behavior Area of Honors: Biology Keywords: imidaclopridneonicotinoidpesticidepollinatorbumble bee File: Download Moak_Thesis_Final.pdf Thesis Supervisors: Christina M Grozinger, Thesis SupervisorSarah Mary Assmann, Thesis Honors Advisor
205. Identifying Cuscuta gronovii trans-species miRNAs Open Access Author: Zakos, Miles Title: Identifying Cuscuta gronovii trans-species miRNAs Area of Honors: Biology Keywords: Cuscuta gronoviitrans-species miRNAsparasitic plantsgene silencing File: Download ZakosThesisFinal2.pdf Thesis Supervisors: Michael Axtell, Thesis SupervisorJames Harold Marden, Thesis Honors Advisor
206. Examination of Dental Histology in the Extinct Shark Archaeolamna kopingensis Open Access Author: Barmore, Lauren Title: Examination of Dental Histology in the Extinct Shark Archaeolamna kopingensis Area of Honors: Biology Keywords: Archaeolamna kopingensisLamniformEnameloidDental HistologyOsteodentineCretaceous File: Download Final_Thesis-Revised.pdf Thesis Supervisors: Todd Donald Cook, Thesis SupervisorMichael A Campbell, Thesis Honors Advisor
207. PFK-158 Increases Migration by Promoting Lipolysis and Fatty Acid Oxidation Open Access Author: Bekker, Jennifer Title: PFK-158 Increases Migration by Promoting Lipolysis and Fatty Acid Oxidation Area of Honors: Biology Keywords: Epithelial-mesenchymal transitionEMTPFK-158metastasiscell migrationcell proliferationcancer cell metabolismlipid metabolismAMPKHGF File: Download Bekker_Jennifer_PFK-158_Increases_Migration_by_Promoting_Lipolysis_and_Fatty_Acid_Oxidation.pdf Thesis Supervisors: Emily Sophia Bell, Thesis SupervisorMichael Axtell, Thesis Honors Advisor
208. Determining the optimal substrate for the invasive New Zealand mud snail (Potamopyrgus antipodarum) Open Access Author: Ghannam, Sally Title: Determining the optimal substrate for the invasive New Zealand mud snail (Potamopyrgus antipodarum) Area of Honors: Biology Keywords: New Zealand mud snailPotamopyrgus antipodaruminvasive speciesecologybiologyperiphytonwoody debrisleaf litterSpirulina algaeoptimal substrate File: Download Ghannam_Sally_Determining_the_Optimal_Substrate_for_the_Invasive_New_Zealand_Mud_Snail__Potamopyrgus_antipodarum_.pdf Thesis Supervisors: Edward P Levri, Thesis SupervisorLaura Rotunno, Thesis Honors AdvisorAllison Cornell, Faculty Reader
209. Combinational Therapy for Acute Lymphoblastic Leukemia with Tyrosine Kinase Inhibitors and Bispecific T Cell Engagers In Vitro Open Access Author: Shaffer, Mikayla Title: Combinational Therapy for Acute Lymphoblastic Leukemia with Tyrosine Kinase Inhibitors and Bispecific T Cell Engagers In Vitro Area of Honors: Biology Keywords: Acute Lymphoblastic LeukemiaBispecific T Cell EngagersTyrosine Kinase Inhibitors File: Download Shaffer_Mikayla_Thesis_FINAL.pdf Thesis Supervisors: Cheng Dong, Thesis SupervisorTimothy J Jegla, Thesis Honors AdvisorJustin R Pritchard, Thesis Supervisor
210. Effect of Signaling Molecules on Strain Diversity of the Euprymna-Vibrio Symbiosis Open Access Author: Ehrig, Molly Title: Effect of Signaling Molecules on Strain Diversity of the Euprymna-Vibrio Symbiosis Area of Honors: Biology Keywords: Quorum SensingEvolutionStrain DiversitySymbiosisVibrio fischeriEuprymna scolopesBacteriaSquid File: Download Ehrig_Molly_Thesis.pdf Thesis Supervisors: Timothy Iwao Miyashiro, Thesis SupervisorYingwei Mao, Thesis Honors Advisor