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Start Over Area of Honors Biochemistry and Molecular Biology

181. An Inside Look on Eutrophication in the Blue Marsh Reservoir by Identifying Cyanobacteria and Their Associated Toxin Genes: A Method to Use Cyanophages to Decrease Harmful Algal Blooms

open_access
Open Access
Author:
Moawad, Rana
Title:
An Inside Look on Eutrophication in the Blue Marsh Reservoir by Identifying Cyanobacteria and Their Associated Toxin Genes: A Method to Use Cyanophages to Decrease Harmful Algal Blooms
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
eutrophication
harmful algal blooms
cyanobacteria
Blue Marsh Reservoir
HABs
cyanophages
water quality
anthropogenic
File:
Download Moawad__Rana_Schreyer_Thesis_May_2022_FINAL_Complete_Submit_.pdf
Thesis Supervisors:
Tami H Mysliwiec, Thesis Supervisor
Sandy Feinstein, Thesis Honors Advisor

182. Exploring the Causes of Muscle Dysfunction Associated with Adenylosuccinate Lyase Deficiency in the Model Organism Caenorhabditis elegans

open_access
Open Access
Author:
Jan, Judy
Title:
Exploring the Causes of Muscle Dysfunction Associated with Adenylosuccinate Lyase Deficiency in the Model Organism Caenorhabditis elegans
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
C. elegans
Muscle Function
Adenylosuccinate Lyase Deficiency
Purine Metabolism
File:
Download Final_Thesis_Draft_Judy_Jan.pdf
Thesis Supervisors:
Wendy Hanna-Rose, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

185. Developing an in vitro Protease Assay for Determining the Transmembrane Topology of SARS-CoV-2 nsp6

open_access
Open Access
Author:
Nasal, Benjamin
Title:
Developing an in vitro Protease Assay for Determining the Transmembrane Topology of SARS-CoV-2 nsp6
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
SARS
COVID
coronavirus
protein topology
transmembrane
protease
microscopy
live cell imaging
western blotting
double membrane vesicle
File:
Download Schreyer_Thesis_FINAL_COPY.pdf
Thesis Supervisors:
Joyce Jose, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

187. The Properties and Location of Anisosome-Forming RNA-binding deficient TAR DNA-binding Protein 43 inside the Nucleus

open_access
Open Access
Author:
Mertick Sykes, Eli
Title:
The Properties and Location of Anisosome-Forming RNA-binding deficient TAR DNA-binding Protein 43 inside the Nucleus
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Protein
Liquid-Liquid Phase Separation
TDP-43
Mammalian Cells
Immunofluorescence
File:
Download Eli_Mertick-Sykes_Thesis_Final.pdf
Thesis Supervisors:
Xin Zhang, Thesis Supervisor
Song Tan, Thesis Honors Advisor

189. Use of Recombinant Urocanase to Study the Inhibitory Effects of Imidazolone Propionate Breakdown Products on Aspartate Aminotransferase

open_access
Open Access
Author:
Ruud, Isabella
Title:
Use of Recombinant Urocanase to Study the Inhibitory Effects of Imidazolone Propionate Breakdown Products on Aspartate Aminotransferase
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
aspartate aminotransferase
urocanase
histidine metabolism
enzyme inhibition
metabolic enzyme deficiencies
File:
Download IAR_Thesis_Final_PDF.pdf
Thesis Supervisors:
Allen T Phillips, Thesis Supervisor
Lorraine C Santy, Thesis Honors Advisor

190. Investigation into the HutD Protein within the Histidine Utilization (hut) Pathway in Pseudomonas putida

open_access
Open Access
Author:
Guzman, Nicholas
Title:
Investigation into the HutD Protein within the Histidine Utilization (hut) Pathway in Pseudomonas putida
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Histidine
Histidine Utilization Pathway (Hut)
HutC
HutD
repressor
promoter
operator
beta-galactosidase
pET vectors
Protein Overexpression
SDS-PAGE
Nickel-IMAC
Molecular Cloning
File:
Download Thesis_Final_Version_-_Guzman.pdf
Thesis Supervisors:
Joseph C. Reese, Thesis Supervisor
Allen T Phillips, Thesis Honors Advisor

192. Is there a Trade-off? Impacts of Antibiotic Treatments on Gut Microbiota and Immune Gene Expression in Honey Bees (Apis Mellifera)

open_access
Open Access
Author:
Tomasko, Nicholas
Title:
Is there a Trade-off? Impacts of Antibiotic Treatments on Gut Microbiota and Immune Gene Expression in Honey Bees (Apis Mellifera)
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Apis mellifera
Oxytetracycline
E. coli
Microbiome
Antimicrobial peptides
Immune genes
Immune response
File:
Download Tomasko_Nicholas_Final_Thesis.pdf
Thesis Supervisors:
Margarita Maria Lopez-Uribe, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

194. AHR Activation Affects Enteric Neuronal Survival by Inducing Apoptosis

open_access
Open Access
Author:
Kumar, Supriya
Title:
AHR Activation Affects Enteric Neuronal Survival by Inducing Apoptosis
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Aryl Hydrocarbon Receptor
TCDD
Enteric Nervous System
Persistant Organic Pollutant
Ceramide Synthesizing Genes
Apoptosis
Longitudinal Muscle Myenteric Plexus
Gut Motility
IM-FEN Cells
Neuronal Marker Genes
Nitrergic Neurons
Cholinergic Neurons
GI Tract
File:
Download Supriya_Kumar_Thesis_AHR_Activation_Affects_Enteric_Neuronal_Survival_by_Inducing_Apoptosis_.pdf
Thesis Supervisors:
Andrew Patterson, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

195. Assessing Sex Bias in Neurodevelopmental Disease-Associated Genes

open_access
Open Access
Author:
Scanlon, Bradley
Title:
Assessing Sex Bias in Neurodevelopmental Disease-Associated Genes
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
genetics
drosophila melanogaster
sex bias
neurodevelopmental diseases
genes
molecular biology
RNA interference
File:
Download Scanlon_Finalthesis.pdf
Thesis Supervisors:
Santhosh Girirajan, Thesis Supervisor
Santhosh Girirajan, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

196. Topic Modeling as an Approach to Deduce Tissue-Specific Regions in the Human Genome

open_access
Open Access
Author:
Patel, Radha
Title:
Topic Modeling as an Approach to Deduce Tissue-Specific Regions in the Human Genome
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Topic Modeling
Transcription Factor Binding
Latent Dirichlet Allocation
Regulatory DNA Sequences
Tissue-Specific Regions
Human Genome
File:
Download final_draft_thesis.pdf
Thesis Supervisors:
Shaun Mahony, Thesis Supervisor
Santhosh Girirajan, Thesis Honors Advisor

197. Synthesis of Phosphatidylinositol 4,5-bisphosphate (PIP2) in Endosomal Compartments during Serum-Stimulated Cell Signaling

open_access
Open Access
Author:
Lee, Ellen
Title:
Synthesis of Phosphatidylinositol 4,5-bisphosphate (PIP2) in Endosomal Compartments during Serum-Stimulated Cell Signaling
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
integrin recycling
epithelial cell migration
cancer
endosomes
File:
Download Lee_Ellen_Thesis2.pdf
Thesis Supervisors:
Lorraine C Santy, Thesis Supervisor
Song Tan, Thesis Honors Advisor

198. The Mechanism of NELF Recruitment by DSIF in Promoter-proximal Pausing of RNA Polymerase II

restricted_to_institution
Restricted (Penn State Only)
Author:
Deng, Eilene
Title:
The Mechanism of NELF Recruitment by DSIF in Promoter-proximal Pausing of RNA Polymerase II
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
promoter-proximal pausing
transcription factors
gene regulation
DSIF
NELF
RNA Polymerase II
File:
Login to Download
Thesis Supervisors:
David Scott Gilmour, Thesis Supervisor
Lorraine C Santy, Thesis Honors Advisor

200. The Effect of the Small RNA RyhB on the Structure of its mRNA Targets

restricted_to_institution
Restricted (Penn State Only)
Author:
Grecco, Samantha
Title:
The Effect of the Small RNA RyhB on the Structure of its mRNA Targets
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
sRNA
RyhB
gene expression profiling
in vivo chemical structure probing
pulldown assay
antibiotic resistance
structure-function relationship
File:
Login to Download
Thesis Supervisors:
Philip C Bevilacqua, Thesis Supervisor
Ying Gu, Thesis Honors Advisor