1. The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism Restricted (Penn State Only) Author: Dennis, Kady Title: The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism Area of Honors: Biochemistry and Molecular Biology Keywords: CX-5461mechanism of actionRNA Polymerase I inhibitorTopoisomerase II poison File: Login to Download Thesis Supervisors: Justin R Pritchard, Thesis SupervisorJoseph C. Reese, Thesis Honors Advisor