1. Mechanisms of FXR Activation by Synthetic Ligands Restricted (Penn State Only) Author: Meinert, Emily Title: Mechanisms of FXR Activation by Synthetic Ligands Area of Honors: Biochemistry and Molecular Biology Keywords: nuclear receptorssite-directed mutagenesisdual luciferasetransformationmammalian cell culturesynthetic ligandbile acid File: Login to Download Thesis Supervisors: C Denise Okafor, Thesis SupervisorTeh-Hui Kao, Thesis Honors Advisor