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Author:

Altmyer, Madison Jo

Title:

STRUCTURAL ANALYSIS OF IRON (II) AND 2-(OXO)-GLUTARATE-DEPENDENT OXYGENASES WITH ALTERNATIVE REACTIVITIES

Area of Honors:

Science

Keywords:

metalloenzyme
oxygenase
hydroxylation
desaturases
isonitriles
crystallography

File:

Download Altmyer_Final_Thesis.pdf

Thesis Supervisors:

Amie Kathleen Boal, Thesis Supervisor
Dr. Ronald Albert Markle, Thesis Honors Advisor
Joseph M Bollinger Jr., Faculty Reader

Author:

Gandhi, Avani

Title:

Structural analysis and characterization of novel class Id ribonucleotide reductases

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

ribonucleotide reductase
DNA repair
X-ray crystallography
metallocofactor

File:

Download Avani_Gandhi_SHC_Final_Thesis.pdf

Thesis Supervisors:

Amie Kathleen Boal, Thesis Supervisor
Teh-Hui Kao, Thesis Honors Advisor

Author:

Pendyala, Jay Venkata

Title:

How Does NfuA Regenerate a [4Fe-4S] Cluster in Lipoyl Synthase?

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

LipA
NfuA
radical SAM
lipoic acid
iron-sulfur cluster

File:

Download Pendyala_Jay__How_Does_NfuA_Regenerate_a__4Fe-4S__Cluster_in_Lipoyl_Synthase.pdf

Thesis Supervisors:

Amie Kathleen Boal, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

Author:

Wertz, Adam

Title:

Structural and Functional Analysis of Two Novel Iron- and Oxygen-Dependent Halogenases

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

Enzyme Structure
Halogenases
BesD
Wel05
Homology
Bioinformatics

File:

Download Thesis_FINAL_Wertz__1_.pdf

Thesis Supervisors:

Amie Kathleen Boal, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

Author:

Katch, Bryce

Title:

Mechanistic Study of Halogenation by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

Enzymology
Structural Biology
C-H Activation
SadA
BesD

File:

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Thesis Supervisors:

Amie Kathleen Boal, Thesis Supervisor
Timothy Charles Meredith, Thesis Honors Advisor

Author:

Fitzpatrick, Lara

Title:

The Functional and Structural Characterization of Novel Diiron Oxidases

Area of Honors:

Chemistry

Keywords:

VarO
Desaturase
Diiron Enzyme
Heme Oxygenase-like
Crystallography
C-H Activation
Spectroscopy

File:

Download Fitzpatrick_Lara_TheFunctionalandStructuralCharacterizationofNovelDiironOxidases.pdf

Thesis Supervisors:

Joseph M Bollinger, Jr., Thesis Supervisor
David D Boehr, Thesis Honors Advisor
Amie Kathleen Boal, Faculty Reader