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Start Over Area of Honors Biomedical Engineering Year 2020

1. The Effect of Lamin A/C and the LINC Complex on TGFβ1-Induced Epithelial to Mesenchymal Transition

open_access
Open Access
Author:
Ling, Melissa
Title:
The Effect of Lamin A/C and the LINC Complex on TGFβ1-Induced Epithelial to Mesenchymal Transition
Area of Honors:
Biomedical Engineering
Keywords:
Epithelial-Mesenchymal Transition
Lamin A/C
TGFβ1
LINC Complex
SUN2
Nuclear Mechanotransduction
File:
Download Final_Thesis_Draft_2020-05-11_Ling.pdf
Thesis Supervisors:
Esther Winter Gomez, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor
Spencer Szczesny, Faculty Reader

3. Analyzing Calcium Deposition on Titanium Surfaces

open_access
Open Access
Author:
Shah, Vraj
Title:
Analyzing Calcium Deposition on Titanium Surfaces
Area of Honors:
Biomedical Engineering
Keywords:
Calcium Deposition
Roughened Titanium Surfaces
Osteogenic Regeneration
Macro-micro textured surface (MM)
Macro-micro-nano textured surface (MMN)
Vraj Shah
File:
Download Analyzing_Calcium_Deposiiton_on_TItanium_Surfaces_ShahVraj.pdf
Thesis Supervisors:
Justin Lee Brown, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Sarah C Ritter, Faculty Reader

4. A Study of the Effect of Hematocrit on an Elevated Beat Rate in the 12cc Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Houtz, Brady
Title:
A Study of the Effect of Hematocrit on an Elevated Beat Rate in the 12cc Penn State Pediatric Ventricular Assist Device
Area of Honors:
Biomedical Engineering
Keywords:
PVAD
artificial heart
cardiovascular
fluid dynamics
beat rate
hematocrit
File:
Download Houtz_SchreyerThesis.pdf
Thesis Supervisors:
Keefe B Manning, Thesis Supervisor
William O Hancock, Thesis Honors Advisor
William Joseph Weiss, Faculty Reader

7. Development of an in vitro culture and loading protocol to study the mechanobiology of rabbit anterior cruciate ligaments

open_access
Open Access
Author:
Carrozzi, Sabrina
Title:
Development of an in vitro culture and loading protocol to study the mechanobiology of rabbit anterior cruciate ligaments
Area of Honors:
Biomedical Engineering
Keywords:
anterior cruciate ligament
ACL
mechanobiology
ligament
tendon
allograft
autograft
biomechanics
File:
Download Final_Schreyer_Thesis.pdf
Thesis Supervisors:
Spencer Szczesny, Thesis Supervisor
William O Hancock, Thesis Honors Advisor

8. Engineering Biomimetic Anticancer Therapies

open_access
Open Access
Author:
Aronson, Matthew
Title:
Engineering Biomimetic Anticancer Therapies
Area of Honors:
Biomedical Engineering
Keywords:
De novo design
anticancer peptides
supramolecular assembly
nanostructures
combinatorial therapy
de novo design
anticancer peptides
supramolecular assembly
nanostructures
combinatorial therapy
drug delivery
nanomedicine
File:
Download Aronson_Thesis_Final.pdf
Thesis Supervisors:
Scott H Medina, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Deb Kelly, Faculty Reader

9. Building 3D Structural Density Maps of p53 Obtained From U-87 MG Glioblastoma Cell Line

open_access
Open Access
Author:
Evans, Madison
Title:
Building 3D Structural Density Maps of p53 Obtained From U-87 MG Glioblastoma Cell Line
Area of Honors:
Biomedical Engineering
Keywords:
p53 tetramer
p53 dimer
Glioblastoma Multiforme cancer
protein structural construction
cryo-EM
negative staining
TEM.
p53 tetramer
p53 dimer
Glioblastoma Multiforme (GBM) cancer
protein structural construction
cryo-EM
negative staining
TEM
File:
Download Evans_Madison_Building_3D_Structural_Density_Maps_of_p53_Obtained_From_U87_MG_GBM_Cell_Line.pdf
Thesis Supervisors:
Deb Kelly, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor

10. Modeling the Dynamics of Elk Subfamily Ion Channels for Physiological Modulation

open_access
Open Access
Author:
Deal, Jack
Title:
Modeling the Dynamics of Elk Subfamily Ion Channels for Physiological Modulation
Area of Honors:
Biomedical Engineering
Keywords:
Elk
Voltage-Gated Ion Channels
Heme
Kinetic Model
Axon Initial Segment
Gating Mechanism
Boltzmann
Affinity
Drosophila melanogaster
Ankyrin
Fluorescent Microscopy
Xenopus
Potassium Channels
File:
Download Jack_Deal_Modeling_the_Dynamics_of_Elk_Subfamily_Ion_Channels_for_Physiological_Modulation.pdf
Thesis Supervisors:
Timothy J Jegla, Thesis Supervisor
William O Hancock, Thesis Honors Advisor