1. MODELING SERUM-DRUG KINETICS FOR THE PREDICTION OF CANCER RESISTANCE TO SECOND LINE THERAPEUTICS Open Access Author: Mc Ilroy, Kyle Title: MODELING SERUM-DRUG KINETICS FOR THE PREDICTION OF CANCER RESISTANCE TO SECOND LINE THERAPEUTICS Area of Honors: Biomedical Engineering Keywords: Cancer File: Download KyleChristopherMcIlroy_SchreyerThesis.pdf Thesis Supervisors: Justin R Pritchard, Thesis SupervisorDr. William O Hancock, Thesis Honors AdvisorDeb Kelly, Faculty Reader
2. An Exploration of Ancient Kinases and a Meta-Analysis of the Modern Use of Tyrosine Kinase Inhibitors in the Literature Open Access Author: Abello, Kerry Title: An Exploration of Ancient Kinases and a Meta-Analysis of the Modern Use of Tyrosine Kinase Inhibitors in the Literature Area of Honors: Biomedical Engineering Keywords: KinasesTyrosine KinasesSrcAblCancerTyrosine Kinase InhibitorImatinibPharmacokineticsSerum BindingProtein Binding File: Download Abello_Kerry_An_Exploration_of_Ancient_Kinases_and_a_Meta-Analysis_of_the_Modern_Use_of_Tyrosine_Kinase_Inhibitors_in_the_Literature.pdf Thesis Supervisors: Justin R Pritchard, Thesis SupervisorJustin Lee Brown, Thesis Honors Advisor
3. Analytical Modeling Study of Acute Lymphoblastic Leukemia Treatment with Blinatumomab and Tyrosine Kinase Inhibitors Open Access Author: Onweller, Lauren Title: Analytical Modeling Study of Acute Lymphoblastic Leukemia Treatment with Blinatumomab and Tyrosine Kinase Inhibitors Area of Honors: Biomedical Engineering Keywords: TKIBiTECancerCombination TherapyMatlab File: Download Analytical_Modeling_Study_of_Acute_Lymphoblastic_Leukemia_Treatment_with_Blinatumomab_and_Tyrosine_Kinase_Inhibitors.pdf Thesis Supervisors: Cheng Dong, Thesis SupervisorMeghan Vidt, Thesis Honors AdvisorJustin R Pritchard, Thesis Supervisor
4. Stochastic Simulations of Tumor Progression Under Targeted Therapy Suggest a Tradeoff Between Evolutionary Trajectories Open Access Author: Liu, Mengde Title: Stochastic Simulations of Tumor Progression Under Targeted Therapy Suggest a Tradeoff Between Evolutionary Trajectories Area of Honors: Biomedical Engineering Keywords: CancerBiomedical EngineeringComputational Modeling File: Download Thesis_MLiu041222.pdf Thesis Supervisors: Justin R Pritchard, Thesis SupervisorJian Yang, Thesis Honors Advisor
5. Effects of Thrombin on the Mechanical Properties of Clots Open Access Author: Elko, Evan Title: Effects of Thrombin on the Mechanical Properties of Clots Area of Honors: Biomedical Engineering Keywords: ThrombinCoagulationRotational ThromboelastometryMechanical TestingThrombosis File: Download Evan_Elko_SHC_Thesis_Final.pdf Thesis Supervisors: Keefe B Manning, Thesis SupervisorJian Yang, Thesis Honors AdvisorJustin R Pritchard, Faculty Reader
6. Investigation of Dual-Switch Combination Therapy’s Efficacy in Drug Resistant Cancer Cells Restricted (Penn State Only) Author: Yang, Zeyu Title: Investigation of Dual-Switch Combination Therapy’s Efficacy in Drug Resistant Cancer Cells Area of Honors: Biomedical Engineering Keywords: Drug resistanceSuicide gene therapyCombination therapyNSCLCEGFR File: Login to Download Thesis Supervisors: Justin R Pritchard, Thesis SupervisorJian Yang, Thesis Honors Advisor