1. Developing an in vitro Protease Assay for Determining the Transmembrane Topology of SARS-CoV-2 nsp6 Open Access Author: Nasal, Benjamin Title: Developing an in vitro Protease Assay for Determining the Transmembrane Topology of SARS-CoV-2 nsp6 Area of Honors: Biochemistry and Molecular Biology Keywords: SARSCOVIDcoronavirusprotein topologytransmembraneproteasemicroscopylive cell imagingwestern blottingdouble membrane vesicle File: Download Schreyer_Thesis_FINAL_COPY.pdf Thesis Supervisors: Joyce Jose, Thesis SupervisorJoseph C. Reese, Thesis Honors Advisor
2. Investigation into the HutD Protein within the Histidine Utilization (hut) Pathway in Pseudomonas putida Open Access Author: Guzman, Nicholas Title: Investigation into the HutD Protein within the Histidine Utilization (hut) Pathway in Pseudomonas putida Area of Honors: Biochemistry and Molecular Biology Keywords: HistidineHistidine Utilization Pathway (Hut)HutCHutDrepressorpromoteroperatorbeta-galactosidasepET vectorsProtein OverexpressionSDS-PAGENickel-IMACMolecular Cloning File: Download Thesis_Final_Version_-_Guzman.pdf Thesis Supervisors: Joseph C. Reese, Thesis SupervisorAllen T Phillips, Thesis Honors Advisor
3. The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism Restricted (Penn State Only) Author: Dennis, Kady Title: The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism Area of Honors: Biochemistry and Molecular Biology Keywords: CX-5461mechanism of actionRNA Polymerase I inhibitorTopoisomerase II poison File: Login to Download Thesis Supervisors: Justin R Pritchard, Thesis SupervisorJoseph C. Reese, Thesis Honors Advisor