1. Antiproliferative Effect of Ascorbate on Breast Epithelial Cells Acts via a Pro-Oxidant Mechanism of Hydrogen Peroxide Production Open Access Author: Martin, Robert Joseph Title: Antiproliferative Effect of Ascorbate on Breast Epithelial Cells Acts via a Pro-Oxidant Mechanism of Hydrogen Peroxide Production Area of Honors: Letters, Arts, and Sciences (Abington) Keywords: ascorbatevitamin chydrogen peroxideglutathioneMCF-10FE2C5T4breast epithelial cell linescatalaseadjuvantantiproliferativepro-oxidantin vitroGLUT1GLUT3dehydroascorbateoxidativeoxidative stressoxidative phosphorylationglycolysis5-mM10-mMmilimolar concentrationsreactive oxygen speciessuper oxidesfree radicalsredoxredox reactionsGAPDH File: Download Final_Thesis.pdf Thesis Supervisors: Dr. Eric Paul Ingersoll, Thesis SupervisorDr. David E Ruth, Thesis Honors AdvisorDr. Thomas McGuire, Faculty Reader