1. The Role of Matrix Stiffness in Regulating SUN2 and P-Lamin A/C During TGFβ1-Induced Epithelial-Mesenchymal Transition Restricted (Penn State Only) Author: Chen, Davon Title: The Role of Matrix Stiffness in Regulating SUN2 and P-Lamin A/C During TGFβ1-Induced Epithelial-Mesenchymal Transition Area of Honors: Chemical Engineering Keywords: SUN2Matrix StiffnessP-Lamin A/CCell ContractilityTGFβ1Epithelial-Mesenchymal TransitionY27632 ROCK Inhibitor File: Login to Download Thesis Supervisors: Michael John Janik, Thesis SupervisorEsther Gomez, Thesis Honors Advisor
2. Analysis of the Structural Role of Key Cell Wall Components in Arabidopsis thaliana via SAXS and GIWAXS Restricted (Penn State Only) Author: Martin, Benjamin Title: Analysis of the Structural Role of Key Cell Wall Components in Arabidopsis thaliana via SAXS and GIWAXS Area of Honors: Chemical Engineering Keywords: SAXSGIWAXSArabidopsis thalianaCell WallPectinCelluloseXyloglucanGrowth MediaMethyl Esterification File: Login to Download Thesis Supervisors: Esther Gomez, Thesis SupervisorMichael John Janik, Thesis Honors Advisor
3. Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Restricted (Penn State Only) Author: Adetayo, Olutomilola Title: Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Area of Honors: Chemical Engineering Keywords: BRCA1breast cancersynthetic lethalityBRCA1 localizationBRCA1 focinuclear areanuclear intensitychromatin remodellingchromatin organizationtissue viscoelasticitychemotherapyselective cancer therapyetoposideBRCA1 and etoposideextracellular matrixhydrogelsviscoelastic hydrogelsDNA damageDNA repair mechanisms File: Login to Download Thesis Supervisors: Esther Gomez, Thesis SupervisorMichael John Janik, Thesis Honors Advisor
4. Investigating the Effects of Tissue Stiffness on Cancer Cell Dormancy Restricted (Penn State Only) Author: Pirog, Angelica Title: Investigating the Effects of Tissue Stiffness on Cancer Cell Dormancy Area of Honors: Chemical Engineering Keywords: matrix stiffnessproliferationapoptosisKi67caspase-3breast cancerdormancyhydrogelYoung's Modulus File: Login to Download Thesis Supervisors: Esther Gomez, Thesis SupervisorDarrell Velegol, Thesis Honors Advisor
5. The Effect of Matrix Viscoelasticity on Epithelial-Mesenchymal Transition, Apoptosis, and Genomic Instability. Restricted (Penn State Only) Author: Vaneman, Zachary Title: The Effect of Matrix Viscoelasticity on Epithelial-Mesenchymal Transition, Apoptosis, and Genomic Instability. Area of Honors: Chemical Engineering Keywords: Disease ProgressionEpithelial-Mesenchymal TransitionCell MigrationViscoelastic Hydrogels File: Login to Download Thesis Supervisors: Esther Gomez, Thesis SupervisorMichael John Janik, Thesis Honors Advisor