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Author:

Adetayo, Olutomilola

Title:

Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci

Area of Honors:

Chemical Engineering

Keywords:

BRCA1
breast cancer
synthetic lethality
BRCA1 localization
BRCA1 foci
nuclear area
nuclear intensity
chromatin remodelling
chromatin organization
tissue viscoelasticity
chemotherapy
selective cancer therapy
etoposide
BRCA1 and etoposide
extracellular matrix
hydrogels
viscoelastic hydrogels
DNA damage
DNA repair mechanisms

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Thesis Supervisors:

Esther Gomez, Thesis Supervisor
Michael John Janik, Thesis Honors Advisor

Author:

Pirog, Angelica

Title:

Investigating the Effects of Tissue Stiffness on Cancer Cell Dormancy

Area of Honors:

Chemical Engineering

Keywords:

matrix stiffness
proliferation
apoptosis
Ki67
caspase-3
breast cancer
dormancy
hydrogel
Young's Modulus

File:

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Thesis Supervisors:

Esther Gomez, Thesis Supervisor
Darrell Velegol, Thesis Honors Advisor