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Author:

Martin, Robert Joseph

Title:

Antiproliferative Effect of Ascorbate on Breast Epithelial Cells Acts via a Pro-Oxidant Mechanism of Hydrogen Peroxide Production

Area of Honors:

Letters, Arts, and Sciences (Abington)

Keywords:

ascorbate
vitamin c
hydrogen peroxide
glutathione
MCF-10F
E2
C5
T4
breast epithelial cell lines
catalase
adjuvant
antiproliferative
pro-oxidant
in vitro
GLUT1
GLUT3
dehydroascorbate
oxidative
oxidative stress
oxidative phosphorylation
glycolysis
5-mM
10-mM
milimolar concentrations
reactive oxygen species
super oxides
free radicals
redox
redox reactions
GAPDH

File:

Download Final_Thesis.pdf

Thesis Supervisors:

Dr. Eric Paul Ingersoll, Thesis Supervisor
Dr. David E Ruth, Thesis Honors Advisor
Dr. Thomas McGuire, Faculty Reader