1. A Biochemical Analysis of Transcription-coupled Repair Proteins in Yeast and their Role in Transcription Elongation and mrna degradation Open Access Author: Wing, Anna Kait Title: A Biochemical Analysis of Transcription-coupled Repair Proteins in Yeast and their Role in Transcription Elongation and mrna degradation Area of Honors: Biochemistry and Molecular Biology Keywords: biochemistrytranscriptiontranscription-coupled repairDNA repairmRNA degradationCcr4-Not complexDNA damage File: Download Wing_Anna_biochemicalanalysisoftcrproteins.pdf Thesis Supervisors: Joseph C. Reese, Thesis SupervisorCraig Eugene Cameron, Thesis Honors AdvisorScott Brian Selleck, Faculty Reader
2. Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Restricted (Penn State Only) Author: Adetayo, Olutomilola Title: Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Area of Honors: Chemical Engineering Keywords: BRCA1breast cancersynthetic lethalityBRCA1 localizationBRCA1 focinuclear areanuclear intensitychromatin remodellingchromatin organizationtissue viscoelasticitychemotherapyselective cancer therapyetoposideBRCA1 and etoposideextracellular matrixhydrogelsviscoelastic hydrogelsDNA damageDNA repair mechanisms File: Login to Download Thesis Supervisors: Esther Gomez, Thesis SupervisorMichael John Janik, Thesis Honors Advisor