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Start Over Area of Honors Chemical Engineering Keyword breast cancer

1. Effects of Extracellular Matrix Rigidity on the Sensitivity of the Aryl Hydrocarbon Receptor in Breast Cancer Cells

open_access
Open Access
Author:
Pezzulo, Joshua Daniel
Title:
Effects of Extracellular Matrix Rigidity on the Sensitivity of the Aryl Hydrocarbon Receptor in Breast Cancer Cells
Area of Honors:
Chemical Engineering
Keywords:
mcf7
extracellular matrix
breast cancer
cyp1a1
ahr
immunofluorescence
western blot
dim
cells
emt
epithelial
mesenchymal
transition
mts
cruciferous
vegetables
indole
polyacrylamide
File:
Download Pezzulo_Thesis_Final_2_.pdf
Thesis Supervisors:
Wayne Roger Curtis, Thesis Honors Advisor
Esther Gomez, Thesis Supervisor

2. Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci

restricted_to_institution
Restricted (Penn State Only)
Author:
Adetayo, Olutomilola
Title:
Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci
Area of Honors:
Chemical Engineering
Keywords:
BRCA1
breast cancer
synthetic lethality
BRCA1 localization
BRCA1 foci
nuclear area
nuclear intensity
chromatin remodelling
chromatin organization
tissue viscoelasticity
chemotherapy
selective cancer therapy
etoposide
BRCA1 and etoposide
extracellular matrix
hydrogels
viscoelastic hydrogels
DNA damage
DNA repair mechanisms
File:
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Thesis Supervisors:
Esther Gomez, Thesis Supervisor
Michael John Janik, Thesis Honors Advisor