1. Effects of Extracellular Matrix Rigidity on the Sensitivity of the Aryl Hydrocarbon Receptor in Breast Cancer Cells Open Access Author: Pezzulo, Joshua Daniel Title: Effects of Extracellular Matrix Rigidity on the Sensitivity of the Aryl Hydrocarbon Receptor in Breast Cancer Cells Area of Honors: Chemical Engineering Keywords: mcf7extracellular matrixbreast cancercyp1a1ahrimmunofluorescencewestern blotdimcellsemtepithelialmesenchymaltransitionmtscruciferousvegetablesindolepolyacrylamide File: Download Pezzulo_Thesis_Final_2_.pdf Thesis Supervisors: Wayne Roger Curtis, Thesis Honors AdvisorEsther Gomez, Thesis Supervisor
2. Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Restricted (Penn State Only) Author: Adetayo, Olutomilola Title: Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Area of Honors: Chemical Engineering Keywords: BRCA1breast cancersynthetic lethalityBRCA1 localizationBRCA1 focinuclear areanuclear intensitychromatin remodellingchromatin organizationtissue viscoelasticitychemotherapyselective cancer therapyetoposideBRCA1 and etoposideextracellular matrixhydrogelsviscoelastic hydrogelsDNA damageDNA repair mechanisms File: Login to Download Thesis Supervisors: Esther Gomez, Thesis SupervisorMichael John Janik, Thesis Honors Advisor
3. Engineering Periodontal Ligament Synthesis Through Environmental Modulation of Stem Cells Open Access Author: Runkle, Leeann Title: Engineering Periodontal Ligament Synthesis Through Environmental Modulation of Stem Cells Area of Honors: Biomedical Engineering Keywords: periodontal ligamentnanofiber surfaceregenerative engineeringextracellular matrix File: Download Runkle_Thesis.pdf Thesis Supervisors: Justin Lee Brown, Thesis SupervisorJustin Lee Brown, Thesis Honors AdvisorLauren Griggs, Faculty ReaderMark D. Pacey, Faculty Reader