1. Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Restricted (Penn State Only) Author: Adetayo, Olutomilola Title: Understanding the Role of BRCA1 in Breast Cancer Progression: Evaluating the Effect of Tissue Viscoelasticity on BRCA1 Localization and Foci Area of Honors: Chemical Engineering Keywords: BRCA1breast cancersynthetic lethalityBRCA1 localizationBRCA1 focinuclear areanuclear intensitychromatin remodellingchromatin organizationtissue viscoelasticitychemotherapyselective cancer therapyetoposideBRCA1 and etoposideextracellular matrixhydrogelsviscoelastic hydrogelsDNA damageDNA repair mechanisms File: Login to Download Thesis Supervisors: Esther Gomez, Thesis SupervisorMichael John Janik, Thesis Honors Advisor
