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1. The Effect Of Overweight And Obesity On Adiponectin Levels And Its Association To Colon And Pancreatic Cancers

open_access
Open Access
Author:
Olock, Brittany Victoria
Title:
The Effect Of Overweight And Obesity On Adiponectin Levels And Its Association To Colon And Pancreatic Cancers
Area of Honors:
Nutritional Sciences
Keywords:
adiponectin
colon cancer
breast cancer
in vitro
cell proliferation
File:
Download Olock_Brittany_effectsofadiponectin.pdf
Thesis Supervisors:
Connie Jo Rogers, Thesis Supervisor
Rebecca L Corwin, Thesis Honors Advisor

2. Determining If Serum Shock and Dexamethasone Initiate Circadian Rhythms in Bovine MAC-T Mammary Epithelial Cells

open_access
Open Access
Author:
Reineke, Rachel A
Title:
Determining If Serum Shock and Dexamethasone Initiate Circadian Rhythms in Bovine MAC-T Mammary Epithelial Cells
Area of Honors:
Veterinary and Biomedical Sciences
Keywords:
circadian rhythms
dexamethasone
serum shock
biological rhythms
dairy
nutrition
cell culture
in vitro
MAC-T
entrained rhythm
peripheral clock
bovine
mammary
epithelial
cells
circadian
rhythm
milk
production
gene expression
RPS9
CLOCK
BMAL1
PER1
PER2
CRY1
File:
Download SHC_Thesis_Final_FINAL_ACTUAL___.pdf
Thesis Supervisors:
Dr. Kevin John Harvatine, Thesis Supervisor
Dr. Lester C Griel Jr., Thesis Honors Advisor

3. Antiproliferative Effect of Ascorbate on Breast Epithelial Cells Acts via a Pro-Oxidant Mechanism of Hydrogen Peroxide Production

open_access
Open Access
Author:
Martin, Robert Joseph
Title:
Antiproliferative Effect of Ascorbate on Breast Epithelial Cells Acts via a Pro-Oxidant Mechanism of Hydrogen Peroxide Production
Area of Honors:
Letters, Arts, and Sciences (Abington)
Keywords:
ascorbate
vitamin c
hydrogen peroxide
glutathione
MCF-10F
E2
C5
T4
breast epithelial cell lines
catalase
adjuvant
antiproliferative
pro-oxidant
in vitro
GLUT1
GLUT3
dehydroascorbate
oxidative
oxidative stress
oxidative phosphorylation
glycolysis
5-mM
10-mM
milimolar concentrations
reactive oxygen species
super oxides
free radicals
redox
redox reactions
GAPDH
File:
Download Final_Thesis.pdf
Thesis Supervisors:
Dr. Eric Paul Ingersoll, Thesis Supervisor
Dr. David E Ruth, Thesis Honors Advisor
Dr. Thomas McGuire, Faculty Reader

5. Clinically Irrelevant Concentrations of Kinase Inhibitors Contribute to Failure of Drug Repurposing Efforts in Clinical Trials: a Meta-Analysis

open_access
Open Access
Author:
Shah, Anushka
Title:
Clinically Irrelevant Concentrations of Kinase Inhibitors Contribute to Failure of Drug Repurposing Efforts in Clinical Trials: a Meta-Analysis
Area of Honors:
Biology
Keywords:
clinical trials
repurposing
cancer
kinase inhibitors
meta-analysis
biology
in vitro
drug concentrations
File:
Download Shah_SHCThesis.pdf
Thesis Supervisors:
Justin R Pritchard, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor