1. An In Vitro Investigation of the Effect of Shear on von Willebrand Factor Proteolysis Open Access Author: Burke, Shannon Leigh Title: An In Vitro Investigation of the Effect of Shear on von Willebrand Factor Proteolysis Area of Honors: Bioengineering Keywords: von Willebrand factorvWFventricular assist deviceVADproteolysisheart failurecardiovascular disease File: Download Shannon_Burke_-_Thesis.pdf Thesis Supervisors: Dr. Keefe B Manning, Thesis SupervisorDr. Keefe B Manning, Thesis Honors AdvisorDr. William O Hancock, Faculty ReaderMargaret June Slattery, Faculty Reader