Simulation of hydrocephalus based on mathematical modeling and technological advancements

Open Access
Author:
Kauffman, Justin Allen
Area of Honors:
Engineering Science
Degree:
Bachelor of Science
Document Type:
Thesis
Thesis Supervisors:
  • Corina Stefania Drapaca, Thesis Supervisor
  • Samia A Suliman, Honors Advisor
  • Judith A Todd, Faculty Reader
Keywords:
  • Hydrocephalus
  • mathematical modeling
  • simulation
Abstract:
Hydrocephalus is a brain disease characterized by abnormalities in the cerebrospinal fluid circulation, resulting in ventricular dilation and brain’s compression. Today’s treatments display no statistically significant difference in their efficacy. Predictive models of brain mechanics can improve therapies. In this thesis we revisit two classic biomechanical models of hydrocephalus by Hakim and Marmarou and present corresponding numerical simulations in a simplified cylindrical geometry for the brain.