Gene Expression of Growth Plate Formation in Mouse Metatarsals
Open Access
Author:
Roberts, Catherine Elizabeth
Area of Honors:
Biological Anthropolgy
Degree:
Bachelor of Science
Document Type:
Thesis
Thesis Supervisors:
Timothy Michael Ryan, Thesis Honors Advisor Philip L Reno, Thesis Supervisor
Keywords:
growth plate development anthropology biology bones skeletal development metatarsals
Abstract:
Growth plates are structures which allow a bone to grow in length. The morphological evolution
of the mammalian skeleton is characterized by changes in bone development, such as the loss or
gain of growth plate formation in a particular bone. Differences in developmental processes are
driven by differential gene expression both during organismal development and throughout their
lifetime. This project uses mouse models to observe the genetic factors correlated with the
presence or absence of growth plate formation in the metatarsal. The aim is to create a working
list of genetic factors related to growth plate development.
