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Start Over Area of Honors Biochemistry and Molecular Biology Thesis Supervisor David Scott Gilmour

1. A Study Of OKL38, A Potential Tumor Suppressor, In Mitochondria Structure and Function

open_access
Open Access
Author:
Tokarski, Anthony Thomas
Title:
A Study Of OKL38, A Potential Tumor Suppressor, In Mitochondria Structure and Function
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
OKL38
tumor suppressor
mitochondria
File:
Download A_Study_of_OKL38_a_potential_tumor_suppressing_protein_in_mitochondrial_structure_and_function.pdf
Thesis Supervisors:
Yanming Wang, Thesis Supervisor
Yanming Wang, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Dr. Wendy Hanna-Rose, Faculty Reader

2. A BIOCHEMICAL ANALYSIS OF THE RNA BINDING ACTIVITY OF Not4 OF THE CCR4-NOT COMPLEX IN YEAST

open_access
Open Access
Author:
Lu, Bonnie Boshen
Title:
A BIOCHEMICAL ANALYSIS OF THE RNA BINDING ACTIVITY OF Not4 OF THE CCR4-NOT COMPLEX IN YEAST
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Not4
Ccr4-Not
yeast
RNA binding
Fluorescence polarization assay
Electrophoretic mobility shift assay
File:
Download Bonnie_Lu_honors_thesis_PSU_May_2011.pdf
Thesis Supervisors:
Joseph C. Reese, Thesis Supervisor
Joseph C. Reese, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Dr. Wendy Hanna-Rose, Faculty Reader

3. GENOME-WIDE DEPENDENCY OF TRANSCRIPTION MACHINERY ON GCN5 IN SACCHAROMYCES CEREVISIAE

open_access
Open Access
Author:
Cantor, David John
Title:
GENOME-WIDE DEPENDENCY OF TRANSCRIPTION MACHINERY ON GCN5 IN SACCHAROMYCES CEREVISIAE
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
transcription machinery genome-wide mapping
Gcn5 deletion
ChIP-exo
SOLiD sequencing
File:
Download Thesis_Final.pdf
Thesis Supervisors:
Benjamin Franklin Pugh, Thesis Supervisor
Benjamin Franklin Pugh, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Dr. Wendy Hanna-Rose, Faculty Reader

4. CONTRIBRUTION OF BK VIRUS miniT PROTEIN TO VIRAL ONCOGENIC ACTIVITY

open_access
Open Access
Author:
Barrantes Gomez, Diana Paola
Title:
CONTRIBRUTION OF BK VIRUS miniT PROTEIN TO VIRAL ONCOGENIC ACTIVITY
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
viral transformation
oncogenic virus
polyomavirus
BK Virus
miniT protein
File:
Download Thesis_Fiinal_I.pdf
Thesis Supervisors:
Richard John Frisque, Thesis Supervisor
Richard John Frisque, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

5. ANALYSIS OF A FUNCTIONAL ROLE FOR CONSERVED LYSINE RESIDUES OF THE H4 N-TERMINUS IN PREMATURE mRNA SPLICING EFFICIENCY

open_access
Open Access
Author:
Joy, Jaimy
Title:
ANALYSIS OF A FUNCTIONAL ROLE FOR CONSERVED LYSINE RESIDUES OF THE H4 N-TERMINUS IN PREMATURE mRNA SPLICING EFFICIENCY
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Histone
H4
splicing
File:
Download Jaimy_Joy_Thesis.pdf
Thesis Supervisors:
Joseph C. Reese, Thesis Supervisor
Joseph C. Reese, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Dr. Wendy Hanna-Rose, Faculty Reader

7. The Overexpression of Complexes and Subcomplexes of the Drosophila melanogaster NELF Proteins

open_access
Open Access
Author:
Hazi, Nathan Christopher
Title:
The Overexpression of Complexes and Subcomplexes of the Drosophila melanogaster NELF Proteins
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
protein expression
NELF
protein purification
HPLC
polycistronic expression plasmid
File:
Download Nathan_Hazi_Thesis.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Song Tan, Thesis Supervisor
Scott Brian Selleck, Faculty Reader

8. MECHANISM AND SPECIFICITY OF MAMMALIAN MITOCHONDRIAL TRANSCRIPTION FACTORS A BINDING TO THE LIGHT-STRAND PROMOTER OF HUMAN MITOCHONDRIAL DNA

open_access
Open Access
Author:
Kumar, Nitin
Title:
MECHANISM AND SPECIFICITY OF MAMMALIAN MITOCHONDRIAL TRANSCRIPTION FACTORS A BINDING TO THE LIGHT-STRAND PROMOTER OF HUMAN MITOCHONDRIAL DNA
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
mitochondrial transcription
transcription factor A
light-strand promoter
File:
Download NitinKumarThesisFinal.pdf
Thesis Supervisors:
Craig Eugene Cameron, Thesis Supervisor
Craig Eugene Cameron, Thesis Supervisor
David Scott Gilmour, Faculty Reader
Craig Eugene Cameron, Thesis Honors Advisor

9. A novel protein-engineering approach for enhancing the crystallization of recalcitrant proteins

open_access
Open Access
Author:
Hostetler, Zachary M
Title:
A novel protein-engineering approach for enhancing the crystallization of recalcitrant proteins
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
structural biology
x-ray crystallography
protein
crystallization
recombinant
fusion
GFP
SUMO
hRCC1
File:
Download Hostetler_Zachary_aNovelProteinEngineeringApproach.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Dr. Wendy Hanna-Rose, Faculty Reader

10. Production and Characterization of Class C Radical Sam Methylases Nosn and Blmorf8

open_access
Open Access
Author:
Gadsby, Lauren Kathryn
Title:
Production and Characterization of Class C Radical Sam Methylases Nosn and Blmorf8
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
SAM
iron-sulfur cluster
radical chemistry
methylase
NosN
BlmOrf8
nosiheptide
bleomycin
S-adenosyl-methionine
File:
Download Thesis_final_edits.pdf
Thesis Supervisors:
Squire J Booker, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

11. Expression and Purification of the HBO1/JADE1 Histone Acetyltransferase Complex

open_access
Open Access
Author:
Tollemar, Viktor Clifford
Title:
Expression and Purification of the HBO1/JADE1 Histone Acetyltransferase Complex
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
protein
expression
complex
hbo1
jade1
biochemistry
molecular biology
nucleosome
File:
Download Expression_and_Purification_of_the_HBO1-JADE1_Histone_Acetyltransferase_Complex.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

12. Purification and Characterization of Human Leucine-Rich Pentatricopeptide Repeat Containing Protein (LRPPRC) Expressed in Escherichia Coli

open_access
Open Access
Author:
Gilmore, Andrew Charles
Title:
Purification and Characterization of Human Leucine-Rich Pentatricopeptide Repeat Containing Protein (LRPPRC) Expressed in Escherichia Coli
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
LRPPRC
Protein
Purification
French Canadian Leigh Syndrome
Escherichia Coli
Mitochondria
File:
Download Gilmore_Purification_and_Characterizaiton_of_LRPPRC_in_E._Coli.pdf
Thesis Supervisors:
Craig Eugene Cameron, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

13. Cloning of Insecticidal BT Genes for Application to Protection of Mushrooms from Fungus Gnats

open_access
Open Access
Author:
Curtis, Matthew Steven
Title:
Cloning of Insecticidal BT Genes for Application to Protection of Mushrooms from Fungus Gnats
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Bacillus thuringiensis
BT
Molecular Cloning
Agaricus bisporus
Mushrooms
Biocontrol
File:
Download Thesis_Matthew_Curtis_BMB.pdf
Thesis Supervisors:
Ming Tien, Thesis Honors Advisor
Dr. Wayne Roger Curtis, Thesis Supervisor
David Scott Gilmour, Faculty Reader
Scott Brian Selleck, Faculty Reader

16. Assessment of Nucleosomal Binding using a High-throughput Interactions by Fluorescent Intensity Assay

open_access
Open Access
Author:
Cognetti, Daniel Joseph
Title:
Assessment of Nucleosomal Binding using a High-throughput Interactions by Fluorescent Intensity Assay
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Gene regulation
Epigenetic
Chromatin
Nucleosome
HI-FI
RCC1
Ran
Histone
Biochemistry
File:
Download Cognetti_Daniel_Assessment.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

17. An examination of behaviors in Drosophila Melanogaster for their utility in an Rnai screen of autism candidate genes

open_access
Open Access
Author:
Saxena, Ritu Shalini
Title:
An examination of behaviors in Drosophila Melanogaster for their utility in an Rnai screen of autism candidate genes
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Autism
Drosophila
Melanogaster
RNAi
screen
gene candidates
behavior
assays
circadian rhythm
geotaxis
social space
File:
Download Ritu_Saxena_BMB_THESIS.pdf
Thesis Supervisors:
Scott Brian Selleck, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

19. Matrix Manipulation Affects Attachment And Growth Of Breast Cancer Cells In A Bone-like Microenvironment In Vitro

open_access
Open Access
Author:
Foster, Shelby Jean
Title:
Matrix Manipulation Affects Attachment And Growth Of Breast Cancer Cells In A Bone-like Microenvironment In Vitro
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
breast cancer
metastasis
bone
estrogen
osteoblast
File:
Download Shelby_Foster_Honors_Thesis.pdf
Thesis Supervisors:
David Scott Gilmour, Thesis Supervisor
Andrea Marie Mastro, Thesis Honors Advisor

20. Role of Heparan Sulfate Proteoglycan Signaling on Autophagy Regulation in Drosophila melanogaster

open_access
Open Access
Author:
Serman, Taryn Mae
Title:
Role of Heparan Sulfate Proteoglycan Signaling on Autophagy Regulation in Drosophila melanogaster
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
HSPG
proteoglycans
autophagy
signaling
cell biology
regulation
File:
Download Taryn_Serman-_Final_Honors_Thesis.pdf
Thesis Supervisors:
Scott Brian Selleck, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

23. Addressing The Role Of The Not4 E3 Ubiquitin Ligase During DNA Damage-Induced Degradation Of RNAPII In Budding Yeast

open_access
Open Access
Author:
Beebe, Laura M
Title:
Addressing The Role Of The Not4 E3 Ubiquitin Ligase During DNA Damage-Induced Degradation Of RNAPII In Budding Yeast
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
DNA Damage Repair
RNA Polymerase
Yeast
Ubiquitin
Ccr4-Not
Gene Regulation
File:
Download Beebe_Laura_Honors_Thesis_sp2017.pdf
Thesis Supervisors:
Joseph C. Reese, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor
David Scott Gilmour, Faculty Reader

24. AN INVESTIGATION OF HYOSCYAMUS NIGER HYOSCYAMINE 6β-HYDROXYLASE ACTIVITY AND IMPROVEMENT OF EXPRESSION METHODS

open_access
Open Access
Author:
Han, Yilin
Title:
AN INVESTIGATION OF HYOSCYAMUS NIGER HYOSCYAMINE 6β-HYDROXYLASE ACTIVITY AND IMPROVEMENT OF EXPRESSION METHODS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Biochemistry
Bioinorganic
H6H
Enzyme
File:
Download Han_Yilin_Thesis.pdf
Thesis Supervisors:
Joseph M Bollinger Jr., Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

25. THE EPIGENETIC REGULATION OF PEPTIDYLARGININE DEIMINASE 4 AND ASSOCIATED CELLULAR RESPONSE PATHWAYS GIVE INSIGHT INTO NOVEL CANCER THERAPEUTICS

open_access
Open Access
Author:
Radaoui, Alexander Brown
Title:
THE EPIGENETIC REGULATION OF PEPTIDYLARGININE DEIMINASE 4 AND ASSOCIATED CELLULAR RESPONSE PATHWAYS GIVE INSIGHT INTO NOVEL CANCER THERAPEUTICS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Cancer
PAD4
Epigenetics
CRISPR-Cas9
Molecular Cloning
File:
Download ALEX_RADAOUI_PDF_b.pdf
Thesis Supervisors:
Yanming Wang, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

26. THE EFFECT OF CYTOHESIN-2/ARNO COILED-COIL DOMAIN MUTATIONS ON ITS INTERACTION WITH SCAFFOLD PROTEINS GRASP AND IPCEF

open_access
Open Access
Author:
Marikunte, Sanjana S
Title:
THE EFFECT OF CYTOHESIN-2/ARNO COILED-COIL DOMAIN MUTATIONS ON ITS INTERACTION WITH SCAFFOLD PROTEINS GRASP AND IPCEF
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Cell Migration
HGF Signaling
ARF6
Cytohesin-2/ARNO
GRASP
IPCEF
File:
Download Marikunte_Sanjana_Honors_Thesis.pdf
Thesis Supervisors:
Dr. Lorraine C Santy, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

27. Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors

open_access
Open Access
Author:
Miller, Sydney Alexis
Title:
Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
trans-translation
hydrazine carbonothiols
antibiotic resistance
File:
Download Thesis.pdf
Thesis Supervisors:
Kenneth Charles Keiler, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

28. Caernorhabditis elegans model for 16p11.2 recurrent microdeletion suggests differential effects of conserved genes to knockdown

open_access
Open Access
Author:
Thomas, Ayush
Title:
Caernorhabditis elegans model for 16p11.2 recurrent microdeletion suggests differential effects of conserved genes to knockdown
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
C. elegans
16p11.2
Autism
Genetics
File:
Download AT_Thesis_SHC.pdf
Thesis Supervisors:
Dr. Santhosh Girirajan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

29. STUDY OF NUCLEOSOME DEPLETING FACTORS ON THE STOCHASTIC EXPRESSION OF THE YEAST HO PROMOTER

open_access
Open Access
Author:
O'Callaghan, Jessica
Title:
STUDY OF NUCLEOSOME DEPLETING FACTORS ON THE STOCHASTIC EXPRESSION OF THE YEAST HO PROMOTER
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Chromatin structure
NDRs
NDFs
Transcription regulation
Gene expression
Single-cell fluorescence microscopy
File:
Download Schreyer_Honors_Thesis.pdf
Thesis Supervisors:
Lu Bai, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

30. Examining Ribosomal Localization based on Microtubule Polarity in Drosophila melanogaster Neurons

open_access
Open Access
Author:
Lee, David Francis
Title:
Examining Ribosomal Localization based on Microtubule Polarity in Drosophila melanogaster Neurons
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Neurons
Drosophila
Ribosomes
Microtubules
Rolls
Lee
Fluorescent Microscopy
Developmental Biology
Biochemistry
Molecular Biology
Neuroscience
Trafficking
File:
Download FINAL.Thesis.Lee.David.pdf
Thesis Supervisors:
Melissa Rolls, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

32. Examining Drosophila melanogaster wing size upon tissue specific RNAi-induced knockdown of candidate gene regions of neurodevelopmental disorders

open_access
Open Access
Author:
Sarker, Avik Moni
Title:
Examining Drosophila melanogaster wing size upon tissue specific RNAi-induced knockdown of candidate gene regions of neurodevelopmental disorders
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Drosophila
neurodevelopmental disorder
CNV
RNAi
UAS/Gal4
deficiency
microdeletion
File:
Download ASarker_Thesis_SHC_Final_Submission.pdf
Thesis Supervisors:
Dr. Santhosh Girirajan, Thesis Supervisor
Dr. Santhosh Girirajan, Thesis Honors Advisor
David Scott Gilmour, Faculty Reader

33. Exploring The Interaction Between Colicin B And The TonB Dependent Transporter FepA Using Colicin B Mutants

open_access
Open Access
Author:
Bhimwal, Rijul
Title:
Exploring The Interaction Between Colicin B And The TonB Dependent Transporter FepA Using Colicin B Mutants
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
TonB
Colicin B
FepA
Outer Membrane
Bacteriocin
Escherichia coli
Gram-negative
File:
Download Rijul_Bhimwal_Honors_Thesis.pdf
Thesis Supervisors:
Kathleen Postle, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

36. Exploring the Causes of Muscle Dysfunction Associated with Adenylosuccinate Lyase Deficiency in the Model Organism Caenorhabditis elegans

open_access
Open Access
Author:
Jan, Judy
Title:
Exploring the Causes of Muscle Dysfunction Associated with Adenylosuccinate Lyase Deficiency in the Model Organism Caenorhabditis elegans
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
C. elegans
Muscle Function
Adenylosuccinate Lyase Deficiency
Purine Metabolism
File:
Download Final_Thesis_Draft_Judy_Jan.pdf
Thesis Supervisors:
Wendy Hanna-Rose, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

38. The Mechanism of NELF Recruitment by DSIF in Promoter-proximal Pausing of RNA Polymerase II

restricted_to_institution
Restricted (Penn State Only)
Author:
Deng, Eilene
Title:
The Mechanism of NELF Recruitment by DSIF in Promoter-proximal Pausing of RNA Polymerase II
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
promoter-proximal pausing
transcription factors
gene regulation
DSIF
NELF
RNA Polymerase II
File:
Login to Download
Thesis Supervisors:
David Scott Gilmour, Thesis Supervisor
Lorraine C Santy, Thesis Honors Advisor

39. Understanding the Mechanisms Controlling the Localization of Microtubule Organization Proteins in Drosophila Neurons

restricted_to_institution
Restricted (Penn State Only)
Author:
Long, Melissa
Title:
Understanding the Mechanisms Controlling the Localization of Microtubule Organization Proteins in Drosophila Neurons
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Drosophila
Neuroscience
Microtubule Nucleation
Clathrin-Mediated Endocytosis
Wnt Signaling
Dendrite
File:
Login to Download
Thesis Supervisors:
Melissa Rolls, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor