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Start Over Area of Honors Bioengineering Degree B S Thesis Supervisor Peter J Butler

1. THE ROLE OF CYTOSKELETON PROTEINS IN THE DETERMINATION OF NEURONAL POLARITY

open_access
Open Access
Author:
Han, Anna Q.
Title:
THE ROLE OF CYTOSKELETON PROTEINS IN THE DETERMINATION OF NEURONAL POLARITY
Area of Honors:
Bioengineering
Keywords:
cytoskeleton proteins
cofilin
slingshot
LIM kinase
neuronal polarity
hippocampal neurons
File:
Download Han.Anna.Spring_2010_Thesis.pdf
Thesis Supervisors:
Dr. Gong Chen, Thesis Supervisor
Dr. Gong Chen, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

4. THE EFFECTS OF THE TUMOR MICROENVIRONMENT ON ENDOTHELIAL CELLULAR ADHESION MOLECULE EXPRESSION

open_access
Open Access
Author:
Goodrich, Christopher James
Title:
THE EFFECTS OF THE TUMOR MICROENVIRONMENT ON ENDOTHELIAL CELLULAR ADHESION MOLECULE EXPRESSION
Area of Honors:
Bioengineering
Keywords:
cancer
metastasis
adhesion
ICAM-1
File:
Download Thesis_Reviewed_Final_-_Christopher_Goodrich.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

5. A Computational Study of Airflow in a Standardized Human Nasal Cavity: Implications Regarding Olfaction

open_access
Open Access
Author:
Shenk, Elizabeth Marie
Title:
A Computational Study of Airflow in a Standardized Human Nasal Cavity: Implications Regarding Olfaction
Area of Honors:
Bioengineering
Keywords:
human olfaction
nasal airflow
standardized human nasal cavity
CFD analysis
File:
Download Shenk_Thesis.pdf
Thesis Supervisors:
Brent A Craven, Thesis Supervisor
Brent A Craven, Thesis Supervisor
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Faculty Reader

6. Preliminary investigation of the effects of arch height on subtalar joint mechanics during walking

open_access
Open Access
Author:
O'Kelly, Katherine Kristen
Title:
Preliminary investigation of the effects of arch height on subtalar joint mechanics during walking
Area of Honors:
Bioengineering
Keywords:
subtalar joint
walking
arch height
ankle
mechanics
File:
Download Honors_Thesis_-_Katherine_K._OKelly.pdf
Thesis Supervisors:
Stephen Jacob Piazza, Thesis Supervisor
Stephen Jacob Piazza, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Jinger S. Gottschall, Faculty Reader

7. Improving Carbon Fiber Microelectrode Performance for Measuring Serotonin by Voltammetry

open_access
Open Access
Author:
Sawarynski, Lauren Elizabeth
Title:
Improving Carbon Fiber Microelectrode Performance for Measuring Serotonin by Voltammetry
Area of Honors:
Bioengineering
Keywords:
serotonin
carbon fiber microelectrodes
voltammetry
File:
Download LSawarynski_FinalThesis.pdf
Thesis Supervisors:
Dr. Anne Milasincic Andrews, Ph D, Thesis Supervisor
Dr. Anne Milasincic Andrews, Ph D, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

8. THE EFFECTS OF MULTIPLE KINESIN MOTORS ON CARGO TRANSPORT VELOCITY

open_access
Open Access
Author:
Bizzaro, Nicholas Robert
Title:
THE EFFECTS OF MULTIPLE KINESIN MOTORS ON CARGO TRANSPORT VELOCITY
Area of Honors:
Bioengineering
Keywords:
motor proteins
kinesin
cellular transport
File:
Download Schreyer_Honors_College_Thesis_-_Nicholas_Bizzaro.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Margaret June Slattery, Faculty Reader

9. THE CHARACTERIZATION OF A MICROCHANNEL DEVICE USING LASER BASED MICRO-PIV

open_access
Open Access
Author:
Wang , Sicong
Title:
THE CHARACTERIZATION OF A MICROCHANNEL DEVICE USING LASER BASED MICRO-PIV
Area of Honors:
Bioengineering
Keywords:
microchannel
microfluidics
micro-PIV
soft lithography
murray law
circulating tumor cell
velocity profile
volumetric flow rate
pulastive flow
PDMS
File:
Download THECHARACTERIZATION_OF_MICROCHANNEL_DEVICE_USING_LASER_BASEDMICROPIV.pdf
Thesis Supervisors:
Siyang Zheng, Thesis Supervisor
Siyang Zheng, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

10. A Foundational Study Of Heart Valve Tissue Engineering: exploration of Natural and Synthetic Scaffold Approaches

open_access
Open Access
Author:
Johnson, Katherine Lynn
Title:
A Foundational Study Of Heart Valve Tissue Engineering: exploration of Natural and Synthetic Scaffold Approaches
Area of Honors:
Bioengineering
Keywords:
Tissue engineering
Bioengineering
heart valve
File:
Download Johnson_Katherine_heartvalvetissue.pdf
Thesis Supervisors:
Dr. George Engelmayr, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Margaret June Slattery, Faculty Reader

11. The effect of bioconjugation of calcium phosphosilicate nanoparticles on breast cancer cell association under shear conditions

open_access
Open Access
Author:
Harter, Lauren Michele
Title:
The effect of bioconjugation of calcium phosphosilicate nanoparticles on breast cancer cell association under shear conditions
Area of Honors:
Bioengineering
Keywords:
nanoparticles
breast cancer
shear conditions
File:
Download Harter_Lauren_bioconjugationCPSNPsbreastcancer.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor

12. An In Vitro Fluid Dynamic Study of a Continuous Flow Device Outlet in Relation to Acquired von Willebrand Syndrome

open_access
Open Access
Author:
Lani, Ryan Anthony
Title:
An In Vitro Fluid Dynamic Study of a Continuous Flow Device Outlet in Relation to Acquired von Willebrand Syndrome
Area of Honors:
Bioengineering
Keywords:
laser Doppler velocimetry (LDV)
HeartMate II
von Willebrand factor (vWF)
ventricular assist devices (VAD)
fluid dynamics
File:
Download Lani_Ryan_An_In_Vitro_Fluid_Dynamic_Study_of_a_Continuous_Flow_Device.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Steven Deutsch, Faculty Reader

13. Magnetic Resonance Imaging as a Diagnostic Tool in the Detection of Diabetic Retinopathy in Mice

open_access
Open Access
Author:
Hobelmann, Kealan Christian
Title:
Magnetic Resonance Imaging as a Diagnostic Tool in the Detection of Diabetic Retinopathy in Mice
Area of Honors:
Bioengineering
Keywords:
MRI
diabetic retinopathy
diabetes
radiofrequency coil
magnetic resonance imaging
File:
Download 1-Hobelmann_Kealan_DiabeticRetinopathyMRI.pdf
Thesis Supervisors:
Thomas Neuberger, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor

16. The Use of Time Correlated Single Photon Counting to Optimize siRNA Encapsulation in Nanoliposomes

open_access
Open Access
Author:
Tanella, Elaine Marie
Title:
The Use of Time Correlated Single Photon Counting to Optimize siRNA Encapsulation in Nanoliposomes
Area of Honors:
Bioengineering
Keywords:
siRNA
nanoliposome
molecular brightness
time correlated single photon counting
fluorescence correlation spectroscopy
File:
Download Elaine_Tanella_thesis.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Margaret June Slattery, Faculty Reader

18. Feasibility Studies for Optical Trap Detection of Single Molecule Adhesion and Force Generation

open_access
Open Access
Author:
Bernick, David J
Title:
Feasibility Studies for Optical Trap Detection of Single Molecule Adhesion and Force Generation
Area of Honors:
Bioengineering
Keywords:
optical trap
laser tweezers
integrin ligand binding
bead
avidin
biotin
microscopy
File:
Download Final_Thesis_Bernick_David_Optical_Trap.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. Keefe B Manning, Faculty Reader
Dr. William O Hancock, Faculty Reader

20. Preliminary Study into Visualization Modalities of von Willebrand Proteolysis in Response to Applied Shear

open_access
Open Access
Author:
Scanlon, Matthew P
Title:
Preliminary Study into Visualization Modalities of von Willebrand Proteolysis in Response to Applied Shear
Area of Honors:
Bioengineering
Keywords:
von Willebrand Factor
vWF
proteolysis
ventricular assist device
cardiovascular disease
visualization
fluorescence
File:
Download Scanlon_Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Steven Deutsch, Faculty Reader

23. A correlative study of fluid mechanics and evidence of thrombus formation within the Penn State 50 cc V-2 left ventricular assist device

open_access
Open Access
Author:
Topper, Stephen Robert
Title:
A correlative study of fluid mechanics and evidence of thrombus formation within the Penn State 50 cc V-2 left ventricular assist device
Area of Honors:
Bioengineering
Keywords:
ventricular assist device
thrombosis
fluid dynamics
pulsatile
wall shear
surface evaluation
particle image velocimetry
File:
Download Topper_Stephen_Schreyer_Honors_Thesis_2012.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Steven Deutsch, Faculty Reader

24. Design By Example: a Web-based Tool for Context-driven Design of Biomedical Devices

open_access
Open Access
Author:
Dzombak, Rachel Victoria
Title:
Design By Example: a Web-based Tool for Context-driven Design of Biomedical Devices
Area of Honors:
Bioengineering
Keywords:
medical devices
developing countries
context
design
bioengineering
africa
Kenya
File:
Download Dzombak_Rachel_DesignByExample_Final.pdf
Thesis Supervisors:
Peter J Butler, Thesis Honors Advisor
Peter J Butler, Thesis Supervisor
Khanjan Mehta, Faculty Reader
Margaret June Slattery, Faculty Reader

25. Finite Element Analysis of Microfabricated Poly(Glycerol Sebacate) Scaffolds for use in Heart Valve Tissue Engineering

open_access
Open Access
Author:
Chowdhury, Surjyanil
Title:
Finite Element Analysis of Microfabricated Poly(Glycerol Sebacate) Scaffolds for use in Heart Valve Tissue Engineering
Area of Honors:
Bioengineering
Keywords:
Chowdhury
finite element
COMSOL
heart valve
tissue engineering
poly glycerol sebacate
PGS
microfabricate
scaffold
mesh
File:
Download honors_thesis_final_draft.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. Keefe B Manning, Faculty Reader

26. Independent On-line Information Processing in Bimanual Coordinated Movements

open_access
Open Access
Author:
Waltz, Lauren Ann
Title:
Independent On-line Information Processing in Bimanual Coordinated Movements
Area of Honors:
Bioengineering
Keywords:
motor control
bimanual coordination
File:
Download Waltz_Lauren_IndependentOnLineInformationProcessing.pdf
Thesis Supervisors:
Robert L Sainburg, Thesis Supervisor
Andrzej Przybyla, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Stephen Jacob Piazza, Faculty Reader

27. The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs)

open_access
Open Access
Author:
Sheldrake, Anne E
Title:
The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs)
Area of Honors:
Bioengineering
Keywords:
MEFs
tissue engineering
cardiac
acrylamide
bisacrylamide
heart
fibrillin
scar tissue
File:
Download sheldrake_anne_effect_of_susbstrate_stiffness.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

33. Fluid Dynamic Studies of a Porcine Aortic Valve in Preparation for Future Living Tissue Valve Studies

open_access
Open Access
Author:
Schmiech, Kathryn Victoria
Title:
Fluid Dynamic Studies of a Porcine Aortic Valve in Preparation for Future Living Tissue Valve Studies
Area of Honors:
Bioengineering
Keywords:
aortic valve
fluid dynamics
porcine valve
particle image velocimetry
File:
Download KSchmiechFinalThesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

34. Investigating the Mechanics of Cancer Cell Membranes Using Microfluidics

open_access
Open Access
Author:
Ramadi, Khalil Basil
Title:
Investigating the Mechanics of Cancer Cell Membranes Using Microfluidics
Area of Honors:
Bioengineering
Keywords:
Cancer
CTC
Isolation
Characterization
Tumor
Membrane
Mechanics
Cell
Expansion
Osmosis
Microfluidics
Viscoelasticity
File:
Download Thesis_Final_final_v2.pdf
Thesis Supervisors:
Siyang Zheng, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

35. Effects of Synonymous, Consecutive, Repetitive Codons on Bacterial Translation Elongation Rates

open_access
Open Access
Author:
Heasley, Victoria Lynn
Title:
Effects of Synonymous, Consecutive, Repetitive Codons on Bacterial Translation Elongation Rates
Area of Honors:
Bioengineering
Keywords:
repetitive codon sequences elongation
affects on translation elongation rates
synthetic biology
genetic engineering
File:
Download Heasley_Victoria__Effects_of_Repetitive_Codons_on_Elongation.pdf
Thesis Supervisors:
Howard M Salis, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

36. Jaipur Foot Project: Computer Simulation for Determination of Static and Cyclic Stresses

open_access
Open Access
Author:
Somers, Sarah Marie
Title:
Jaipur Foot Project: Computer Simulation for Determination of Static and Cyclic Stresses
Area of Honors:
Bioengineering
Keywords:
Jaipur Foot
cyclic stress
fatigue life
prosthetic
File:
Download Somers_Sarah_Jaipur_Foot_Project.pdfDownload Somers_Sarah_JaipurMovie.avi
Thesis Supervisors:
Margaret June Slattery, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Elizabeth Cunningham Kisenwether, Faculty Reader

37. An Experimental Setup to Test the Effects of Shear Stress on von Willebrand Factor

open_access
Open Access
Author:
Corsetti, Monica Claire
Title:
An Experimental Setup to Test the Effects of Shear Stress on von Willebrand Factor
Area of Honors:
Bioengineering
Keywords:
von Willebrand Factor
vWF
Optical Trap
Optical Tweezers
Shear Stress
Acquired von Willebrand Syndrome
ADAMTS-13
File:
Download Thesis_Monica_Corsetti.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Peter J Butler, Faculty Reader
Dr. William O Hancock, Faculty Reader
Dr. Keefe B Manning, Thesis Honors Advisor

38. Nanofiber Control of Focal Adhesion Dynamics and Cell Migration for Regenerative Medicine

open_access
Open Access
Author:
Riley, Thomas Roberts
Title:
Nanofiber Control of Focal Adhesion Dynamics and Cell Migration for Regenerative Medicine
Area of Honors:
Bioengineering
Keywords:
Matlab
Image Processing
Focal Adhesion
Cell Migration
Nanofiber
Tissue Engineering
Regenerative Medicine
FAITS
File:
Download RileyThesisFinalDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

39. Histological Analysis of in vitro Thrombus Formation in a Backward Facing Step Flow Domain Using Carstairs' Stain

open_access
Open Access
Author:
Kinney, Joanna E
Title:
Histological Analysis of in vitro Thrombus Formation in a Backward Facing Step Flow Domain Using Carstairs' Stain
Area of Honors:
Bioengineering
Keywords:
thrombosis
histology
bioengineering
heart
blood
File:
Download Kinney_Joanna_Thesis_Final.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

40. A Fluid Dynamic Study of the Effect of Hematocrit in the 12 cc Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Silver, Jeremy Michael
Title:
A Fluid Dynamic Study of the Effect of Hematocrit in the 12 cc Penn State Pediatric Ventricular Assist Device
Area of Honors:
Bioengineering
Keywords:
ventricular assist device
pediatric
cardiovascular device
hematocrit
thrombosis
particle image velocimetry
piv
VAD
PVAD
File:
Download Silver_SHC_Thesis_FINAL.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader
Peter J Butler, Faculty Reader

41. Localized Thrombus Rheology: A Study Through the Development of a Magnetic Bead Microrheometry System

open_access
Open Access
Author:
Nilkant, Prithvi
Title:
Localized Thrombus Rheology: A Study Through the Development of a Magnetic Bead Microrheometry System
Area of Honors:
Bioengineering
Keywords:
thrombus
blood clot
rheology
elasticity
File:
Download Prithvi_Nilkant_Localized_Thrombus_Rheology_-_A_Study_Through_the_Development_of_a_Magnetic_Bead_Microrheometry_System.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Margaret June Slattery, Faculty Reader

42. Single-molecule microscopy step detection algorithms: kinesin motor proteins and the cellulose synthesis complex

open_access
Open Access
Author:
Deffenbaugh, Nathan C
Title:
Single-molecule microscopy step detection algorithms: kinesin motor proteins and the cellulose synthesis complex
Area of Honors:
Bioengineering
Keywords:
kinesin
motor proteins
step detection
single-molecule
cellulose synthesis complex
hidden Markov model
File:
Download DeffenbaughNathan_SHCThesis_May2015.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Faculty Reader
Dr. Justin Lee Brown, Faculty Reader
Dr. William O Hancock, Thesis Honors Advisor

44. Exploiting Biomarkers Assists in Degradation of Breast Cancer Cells and Reduces Extravasation

open_access
Open Access
Author:
Zaki, Peter Maged
Title:
Exploiting Biomarkers Assists in Degradation of Breast Cancer Cells and Reduces Extravasation
Area of Honors:
Bioengineering
Keywords:
breast cancer
pancreatic cancer
melanoma
nanoparticles
nanoliposomes
docetaxel
ceramide
CD71
CD44
metastasis
File:
Download Thesis_Final.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
James Hansell Adair, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor

45. Computational Modeling of the Effects of Shear Stress on von Willebrand Factor Proteolysis

open_access
Open Access
Author:
Tramontozzi, Michael William
Title:
Computational Modeling of the Effects of Shear Stress on von Willebrand Factor Proteolysis
Area of Honors:
Bioengineering
Keywords:
Biomedical
Engineering
COMSOL
von Willebrand Factor
Ventricular Assist Device
Computational
Optical Trap
Shear
File:
Download Michael_Tramontozzi_-_Thesis_Final.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Margaret June Slattery, Faculty Reader

46. The Investigation of Fluid Shear Stress and Subsequent Conformational Changes of von Willebrand Factor Observed in an Optical Trap

open_access
Open Access
Author:
Candela, Xavier Joseph
Title:
The Investigation of Fluid Shear Stress and Subsequent Conformational Changes of von Willebrand Factor Observed in an Optical Trap
Area of Honors:
Bioengineering
Keywords:
vWF
optical trap
fluid shear
von Willebrand Factor
LVADs
File:
Download FORMATTED_CANDELA_THESIS_PC_version_CORRECT.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Peter J Butler, Faculty Reader

47. Comparing Novel Techniques for Measuring the Bending Modulus of Lipid Bilayer Membranes in Erythrocytes

open_access
Open Access
Author:
Frazzette, Nicholas James
Title:
Comparing Novel Techniques for Measuring the Bending Modulus of Lipid Bilayer Membranes in Erythrocytes
Area of Honors:
Bioengineering
Keywords:
mechanobiology
bending modulus
mechanotransduction
lipid bilayers
membrane bending
erythrocytes
TCSPC
fluorescence
File:
Download Frazzette_SHC_Thesis_v4.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Herbert Herling Lipowsky, Faculty Reader