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1. Examining Effects of PCR Conditions on mtDNA Heteroplasmy Detection Using Next Generation Sequencing

open_access
Open Access
Author:
Rothwell, Lauren Elizabeth
Title:
Examining Effects of PCR Conditions on mtDNA Heteroplasmy Detection Using Next Generation Sequencing
Area of Honors:
Forensic Science
Keywords:
forensic science
DNA
heteroplasmy
pyrosequencing
chimeric sequences
File:
Download LRothwell_ExaminingHeteroplasmy.pdfDownload Rothwell_AdditionalFigures.pdf
Thesis Supervisors:
Dr. Mitchell Mark Holland, Thesis Supervisor
Dr. Mitchell Mark Holland, Thesis Honors Advisor
Ronald D Porter, Faculty Reader

2. Synthetic DNA Promoters to Control Gene Expression Based on the Presence of Oxygen in E. coli

open_access
Open Access
Author:
Kirk, Andrew
Title:
Synthetic DNA Promoters to Control Gene Expression Based on the Presence of Oxygen in E. coli
Area of Honors:
Biological Engineering
Keywords:
synthetic biology
genetic engineering
E. coli
DNA
oxygen-sensitive promoters
ArcA
FNR
dcuC
File:
Download Kirk_Andrew_Synthetic_DNA_Promoters.pdf
Thesis Supervisors:
Dr. Howard M Salis, Thesis Supervisor
Ali Demirci, Thesis Honors Advisor

5. Validation of PRESERVEi™ SwabSqueezer™ Indicating MicroCard for Reliable, Rapid Genotyping of Saliva Reference Samples

open_access
Open Access
Author:
Parchuke, Emily Rose
Title:
Validation of PRESERVEi™ SwabSqueezer™ Indicating MicroCard for Reliable, Rapid Genotyping of Saliva Reference Samples
Area of Honors:
Forensic Science
Keywords:
Forensic science
reference samples
DNA
direct amplification
PCR
genetic analysis
File:
Download Parchuke_Emily_ValidationOfPreserveiSwabSqueezerIndicatingMicrocard.pdf
Thesis Supervisors:
Reena Roy, Thesis Supervisor
Reena Roy, Thesis Honors Advisor
Ralph R Ristenbatt, Faculty Reader

6. Sequencing The Genome Of The Nittany Lion (puma Concolor From Pennsylvania)

open_access
Open Access
Author:
Evanitsky, Maya Nicole
Title:
Sequencing The Genome Of The Nittany Lion (puma Concolor From Pennsylvania)
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
DNA
molecular biology
genetics
mountain lions
puma concolor
ancient DNA
mitochondrial DNA
File:
Download Evanitsky_Maya_Thesis__Final.pdf
Thesis Supervisors:
George H Perry, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Dr. Santhosh Girirajan, Thesis Supervisor

7. Characterizing and Optimizing the Synthesis of 'bubble' Dna-templated Silver Nanoclusters as a Fluorescent Material

open_access
Open Access
Author:
Campbell, Ian Edward
Title:
Characterizing and Optimizing the Synthesis of 'bubble' Dna-templated Silver Nanoclusters as a Fluorescent Material
Area of Honors:
Chemistry
Keywords:
DNA
templated
silver
nanoclusters
fluorescent
optimize
synthesis
stability
chemical yield
File:
Download SHC_THESIS_Ian_Campbell_resub_04182016.pdf
Thesis Supervisors:
Bruce Paul Wittmershaus, Thesis Supervisor
Alan John Jircitano, Thesis Honors Advisor
Darren Williams, Faculty Reader

8. INVESTIGATING RATES OF HETEROPLASMY IN THE MITOCHONDRIAL DNA CONTROL REIGON OF AFRICAN, ASIAN, AND LATINO POPULATION GROUPS USING MASSIVELY PARALLEL SEQUENCING

open_access
Open Access
Author:
Demchak, Emily Louise
Title:
INVESTIGATING RATES OF HETEROPLASMY IN THE MITOCHONDRIAL DNA CONTROL REIGON OF AFRICAN, ASIAN, AND LATINO POPULATION GROUPS USING MASSIVELY PARALLEL SEQUENCING
Area of Honors:
Forensic Science
Keywords:
DNA
mtDNA
Heteroplasmy
NGS
MPS
File:
Download Demchak_Emily_Thesis_mtDNA_heteroplasmic_rates.pdf
Thesis Supervisors:
Dr. Mitchell Mark Holland, Thesis Supervisor
Dr. Mitchell Mark Holland, Thesis Honors Advisor
Jennifer McElhoe, Faculty Reader

10. A Longitudinal Analysis of Antibiotic Resistance in the Sediment Samples of the Delaware River Watershed and in the Clinical Infections in the Reading Hospital

open_access
Open Access
Author:
Sindhar, Safitaj
Title:
A Longitudinal Analysis of Antibiotic Resistance in the Sediment Samples of the Delaware River Watershed and in the Clinical Infections in the Reading Hospital
Area of Honors:
Biology
Keywords:
Antibiotic Resistance
Delaware River Watershed
Tetracycline
Ampicillin
Enterococcus
Escherichia coli
Polymerase Chain Reaction
DNA
Berks County
tet(A)
tet(R)
ctx
oxa
blaP
File:
Download Sindhar_Safitaj_LongitudinalAnalysisofAntibioticResistance.pdf
Thesis Supervisors:
Tami H Mysliwiec, Thesis Supervisor
Sandy Feinstein, Thesis Honors Advisor

11. Engineering Molecular Sensors for The Detection of SOX9, RUNX2, and PPARG Transcription Factors

open_access
Open Access
Author:
Pera Mendes, Joao Paulo
Title:
Engineering Molecular Sensors for The Detection of SOX9, RUNX2, and PPARG Transcription Factors
Area of Honors:
Biomedical Engineering
Keywords:
Nanosensor
Transcription Factor
DNA
Probe
SOX9
RUNX2
PPARG
FRET
iPSC
Molecular
Sensor
GNR
File:
Download FinalThesis_JoaoPauloPeraMendes.pdf
Thesis Supervisors:
Pak Kin Wong, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Daniel J Hayes, Faculty Reader