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4. Antiproliferative Effect of Ascorbate on Breast Epithelial Cells Acts via a Pro-Oxidant Mechanism of Hydrogen Peroxide Production

open_access
Open Access
Author:
Martin, Robert Joseph
Title:
Antiproliferative Effect of Ascorbate on Breast Epithelial Cells Acts via a Pro-Oxidant Mechanism of Hydrogen Peroxide Production
Area of Honors:
Letters, Arts, and Sciences (Abington)
Keywords:
ascorbate
vitamin c
hydrogen peroxide
glutathione
MCF-10F
E2
C5
T4
breast epithelial cell lines
catalase
adjuvant
antiproliferative
pro-oxidant
in vitro
GLUT1
GLUT3
dehydroascorbate
oxidative
oxidative stress
oxidative phosphorylation
glycolysis
5-mM
10-mM
milimolar concentrations
reactive oxygen species
super oxides
free radicals
redox
redox reactions
GAPDH
File:
Download Final_Thesis.pdf
Thesis Supervisors:
Dr. Eric Paul Ingersoll, Thesis Supervisor
Dr. David E Ruth, Thesis Honors Advisor
Dr. Thomas McGuire, Faculty Reader

5. MANIPULATION OF NAD+ IN C. ELEGANS AFFECTS HATCHING, LIFESPAN, AND SENSORY OUTPUT

open_access
Open Access
Author:
La Ganke, Nicole
Title:
MANIPULATION OF NAD+ IN C. ELEGANS AFFECTS HATCHING, LIFESPAN, AND SENSORY OUTPUT
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Nicotinamide adenine dinucleotide
C. elegans
sirtuins
oxidative stress
lifespan
delayed hatching
sensory response
File:
Download LaGanke_Final_Thesis.pdf
Thesis Supervisors:
Dr. Wendy Hanna-Rose, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor

8. Cannabinoids as Neuroprotective Molecules in Photoreceptors following Light-Induced Retinal Degeneration in Zebrafish Retina

open_access
Open Access
Author:
Proano, Renata
Title:
Cannabinoids as Neuroprotective Molecules in Photoreceptors following Light-Induced Retinal Degeneration in Zebrafish Retina
Area of Honors:
Biology
Keywords:
cannabinoids
hemp
CBD
THC
Zebrafish
retina
age related macular degenaration
biology
therapeutic
neuroprotective
anti-inflammatory
rods
cones
photoreceptor
retinal degeneration
light-induced retinal degeneration
CB-13
novel therapy
immunofluorescence
animals
tissue preparation
cryosectioning
oxidative stress
endocannabinoid
receptors
model organism
File:
Download Renata_Proano_Thesis_Final_.pdf
Thesis Supervisors:
Salvatore Lucia Stella, Jr., Thesis Supervisor
Sairam V Rudrabhatla, Thesis Honors Advisor
Nik Tsotakos, Faculty Reader