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Start Over Area of Honors Biochemistry and Molecular Biology Degree B S Year 2017

3. IDENTIFICATION AND VALIDATION OF CRISPR/CAS9 STAGE-SPECIFIC PROMOTERS AND AN ALTERNATIVE FLUORESCENT REPORTER TO GFP FOR PLASMODIUM YOELII

open_access
Open Access
Author:
Bowman, Laura Marie
Title:
IDENTIFICATION AND VALIDATION OF CRISPR/CAS9 STAGE-SPECIFIC PROMOTERS AND AN ALTERNATIVE FLUORESCENT REPORTER TO GFP FOR PLASMODIUM YOELII
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Malaria
Genetically Attenuated Parasites
CRISPR/Cas9
Stage-Specific Promoters
File:
Download Honors_Thesis.pdf
Thesis Supervisors:
Scott Eugene Lindner, Thesis Supervisor
Dr. Wendy Hanna-Rose, Thesis Honors Advisor

4. The regulation of lipid storage by the splicing factor transformer2 (tra2) in Drosophila

open_access
Open Access
Author:
Mikoluk, Cezary
Title:
The regulation of lipid storage by the splicing factor transformer2 (tra2) in Drosophila
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
tra
tra2
transformer
transformer2
drosophila
melanogaster
CPT1
triglyceride
lipid
storage
splicing
factor
9G8
File:
Download Mikoluk_Cezary_tra2.pdf
Thesis Supervisors:
Justin DiAngelo, Thesis Supervisor
Dr. Sandy Feinstein, Thesis Honors Advisor

7. THE EFFECTS OF INTERNAL HISTONE H3 TRUNCATIONS ON LSD1/COREST DEMETHYLASE ACTIVITY

open_access
Open Access
Author:
Johnston, James Lakshman
Title:
THE EFFECTS OF INTERNAL HISTONE H3 TRUNCATIONS ON LSD1/COREST DEMETHYLASE ACTIVITY
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
James
Johnston
James Johnston
Lakshman
LSD1
CoREST
Histone
Chromatin
H3
Truncations
Structure
Nucleosome
File:
Download JamesJohnstonThesisFinalFixed.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

9. ROLE OF COREST N-TERMINAL EXTENSION ON LSD1/COREST DEMETHYLASE ACTIVITY

open_access
Open Access
Author:
Pecen, Turner John
Title:
ROLE OF COREST N-TERMINAL EXTENSION ON LSD1/COREST DEMETHYLASE ACTIVITY
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
LSD1
CoREST
Demethylase
Nucleosome
Binding Assay
Activity Assay
Protein
Biochemistry
Molecular Biology
Complex
File:
Download Pecen_Turner_ROLE_OF_COREST_N-TERMINAL_EXTENSION_ON_LSD1-COREST_DEMETHYLASE_ACTIVITY.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

10. LIPID-MEDIATED LOCALIZATION OF POLIOVIRUS RNA-DEPENDENT RNA POLYMERASE

open_access
Open Access
Author:
Basu, Rohan
Title:
LIPID-MEDIATED LOCALIZATION OF POLIOVIRUS RNA-DEPENDENT RNA POLYMERASE
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Viral replication
poliovirus
replication organelle
3D
RNA-dependent RNA polymerase
File:
Download Basu_Rohan_PV3DThesis.pdf
Thesis Supervisors:
David D Boehr, Thesis Supervisor
Ming Tien, Thesis Honors Advisor
Craig Eugene Cameron, Thesis Supervisor
Scott Brian Selleck, Faculty Reader

11. DEVELOPMENT OF A CRISPR-CAS9 CONSTRUCT AIMED AT KNOCKING OUT SETD2 IN U2OS CELLS

open_access
Open Access
Author:
Schultheis, Nicholas Charles
Title:
DEVELOPMENT OF A CRISPR-CAS9 CONSTRUCT AIMED AT KNOCKING OUT SETD2 IN U2OS CELLS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
CRISPR
CAS9
SETD2
U2OS
H3K36me3
File:
Download Schultheis_Nicholas_Development_of_a_CRISPR-Cas9_Construct_Aimed_At_Knocking_Out_SetD2_in_U2OS_Cells.pdf
Thesis Supervisors:
Yanming Wang, Thesis Supervisor
Dr. Lorraine C Santy, Thesis Honors Advisor

12. CHARACTERIZING REPLICATION PROTEIN RECRUITMENT AT GAA MICROSATELLITE REPEAT IN A MAMMALIAN PRIMARY REPLICATION CYCLE

open_access
Open Access
Author:
Degiosio, Rebecca Anne
Title:
CHARACTERIZING REPLICATION PROTEIN RECRUITMENT AT GAA MICROSATELLITE REPEAT IN A MAMMALIAN PRIMARY REPLICATION CYCLE
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
microsatellite
DNA replication
mammalian
genomic instability
chromatin immunoprecipitation
quantitative PCR
trinucleotide repeat
Friedreich's Ataxia
File:
Download DeGiosio_Rebecca_GAARepRecruit.pdf
Thesis Supervisors:
Maria Krasilnikova, Thesis Supervisor
Dr. Lorraine C Santy, Thesis Honors Advisor

13. Addressing The Role Of The Not4 E3 Ubiquitin Ligase During DNA Damage-Induced Degradation Of RNAPII In Budding Yeast

open_access
Open Access
Author:
Beebe, Laura M
Title:
Addressing The Role Of The Not4 E3 Ubiquitin Ligase During DNA Damage-Induced Degradation Of RNAPII In Budding Yeast
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
DNA Damage Repair
RNA Polymerase
Yeast
Ubiquitin
Ccr4-Not
Gene Regulation
File:
Download Beebe_Laura_Honors_Thesis_sp2017.pdf
Thesis Supervisors:
Joseph C. Reese, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor
David Scott Gilmour, Faculty Reader

14. AN INVESTIGATION OF HYOSCYAMUS NIGER HYOSCYAMINE 6β-HYDROXYLASE ACTIVITY AND IMPROVEMENT OF EXPRESSION METHODS

open_access
Open Access
Author:
Han, Yilin
Title:
AN INVESTIGATION OF HYOSCYAMUS NIGER HYOSCYAMINE 6β-HYDROXYLASE ACTIVITY AND IMPROVEMENT OF EXPRESSION METHODS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Biochemistry
Bioinorganic
H6H
Enzyme
File:
Download Han_Yilin_Thesis.pdf
Thesis Supervisors:
Joseph M Bollinger Jr., Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

15. Novel Forward Osmosis Desalination Technique Involving an Aquaporin Membrane and a Polyethylene-Glycol-Functionalized Iron Oxide Nanoparticle Draw Solute

open_access
Open Access
Author:
Arnett, Nathan Garner Littlefield
Title:
Novel Forward Osmosis Desalination Technique Involving an Aquaporin Membrane and a Polyethylene-Glycol-Functionalized Iron Oxide Nanoparticle Draw Solute
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
desalination
File:
Download Arnett.Final.pdf
Thesis Supervisors:
Tak-Sing Wong, Thesis Supervisor
Ming Tien, Thesis Honors Advisor

16. DE NOVO SYNTHESIS OF NAD+ CONRTIBUTES TO REPRODUCTIVE DEVELOPMENT IN CAENORHABDITIS ELEGANS

open_access
Open Access
Author:
Holleran, Lauren Michelle
Title:
DE NOVO SYNTHESIS OF NAD+ CONRTIBUTES TO REPRODUCTIVE DEVELOPMENT IN CAENORHABDITIS ELEGANS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
NAD+
C. elegans
de novo pathway
reproductive development
gonad delay
brood size
umps-1
File:
Download thesis_final_draft.pdf
Thesis Supervisors:
Dr. Wendy Hanna-Rose, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

17. CHARACTERIZATION OF THE ROLE OF UIS12 IN PLASMODIUM YOELII MALE GAMETOCYTE ACTIVATION

open_access
Open Access
Author:
Vrana, Erin Nicole
Title:
CHARACTERIZATION OF THE ROLE OF UIS12 IN PLASMODIUM YOELII MALE GAMETOCYTE ACTIVATION
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
malaria
Plasmodium yoelii
UIS12
translational repression
Biochemistry and Molecular Biology
File:
Download Honors_Thesis_Vrana_EN_final.pdf
Thesis Supervisors:
Scott Eugene Lindner, Thesis Supervisor
Dr. Sarah Ellen Ades, Thesis Honors Advisor

19. THE EPIGENETIC REGULATION OF PEPTIDYLARGININE DEIMINASE 4 AND ASSOCIATED CELLULAR RESPONSE PATHWAYS GIVE INSIGHT INTO NOVEL CANCER THERAPEUTICS

open_access
Open Access
Author:
Radaoui, Alexander Brown
Title:
THE EPIGENETIC REGULATION OF PEPTIDYLARGININE DEIMINASE 4 AND ASSOCIATED CELLULAR RESPONSE PATHWAYS GIVE INSIGHT INTO NOVEL CANCER THERAPEUTICS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Cancer
PAD4
Epigenetics
CRISPR-Cas9
Molecular Cloning
File:
Download ALEX_RADAOUI_PDF_b.pdf
Thesis Supervisors:
Yanming Wang, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader