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Start Over Area of Honors Biochemistry and Molecular Biology Keyword antibiotic resistance Keyword antibiotic resistance

1. Cloning of the Genes Encoding the Proteins of Lipoyl Cofactor Biosynthesis In Mycobacterium tuberculosis and Characterization of Lipoyl Synthase

open_access
Open Access
Author:
Horstmann, Abigail Kathryn
Title:
Cloning of the Genes Encoding the Proteins of Lipoyl Cofactor Biosynthesis In Mycobacterium tuberculosis and Characterization of Lipoyl Synthase
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
lipoyl synthase
tuberculosis
Mycobacterium tuberculosis
LipA
lipoic acid
antibiotic resistance
File:
Download THESIS-finaldraft.pdf
Thesis Supervisors:
Squire J Booker, Thesis Supervisor
Squire J Booker, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor
Scott Brian Selleck, Faculty Reader

3. Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors

open_access
Open Access
Author:
Miller, Sydney Alexis
Title:
Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
trans-translation
hydrazine carbonothiols
antibiotic resistance
File:
Download Thesis.pdf
Thesis Supervisors:
Kenneth Charles Keiler, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

4. Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors

open_access
Open Access
Author:
Ryan, Taryn Jeanne
Title:
Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
trans-translation
antibiotic resistance
8-hydroxyquinoline
triazole
luciferase-based
click chemistry
File:
Download Taryn_Ryan_Honors_Thesis.pdf
Thesis Supervisors:
Kenneth Charles Keiler, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Dr. Sarah Ellen Ades, Faculty Reader

5. Identification and Characterization of trans-Translation Inhibitors

open_access
Open Access
Author:
Davison, Alexis
Title:
Identification and Characterization of trans-Translation Inhibitors
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
trans-translation
antibiotic resistance
ribosome profiling
KKL-4669
high-throughput screen
luciferase reporter assay
bacterial pathogens
Caulobacter
in vitro transcription/translation assay
File:
Download Davison_Alexis_Thesis_Sp2020.pdf
Thesis Supervisors:
Ken Keiler, Thesis Supervisor
Ying Gu, Thesis Honors Advisor

7. The Effect of the Small RNA RyhB on the Structure of its mRNA Targets

restricted_to_institution
Restricted (Penn State Only)
Author:
Grecco, Samantha
Title:
The Effect of the Small RNA RyhB on the Structure of its mRNA Targets
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
sRNA
RyhB
gene expression profiling
in vivo chemical structure probing
pulldown assay
antibiotic resistance
structure-function relationship
File:
Login to Download
Thesis Supervisors:
Philip C Bevilacqua, Thesis Supervisor
Ying Gu, Thesis Honors Advisor