1. Identifying inhibitors of trans‐translation in methicillin resistant Staphylococcus aureus Open Access Author: Rae, Christopher Donald Title: Identifying inhibitors of trans‐translation in methicillin resistant Staphylococcus aureus Area of Honors: Biochemistry and Molecular Biology Keywords: methicillin resistant Staphylococcus aureusMRSAantibiotictrans-translation File: Download Chris_Rae_Undergraduate_Honors_Thesis.pdf Thesis Supervisors: Kenneth Charles Keiler, Thesis SupervisorCraig Eugene Cameron, Thesis Honors AdvisorScott Brian Selleck, Faculty Reader
2. Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors Open Access Author: Miller, Sydney Alexis Title: Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationhydrazine carbonothiolsantibiotic resistance File: Download Thesis.pdf Thesis Supervisors: Kenneth Charles Keiler, Thesis SupervisorDavid Scott Gilmour, Thesis Honors Advisor
3. Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors Open Access Author: Ryan, Taryn Jeanne Title: Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibiotic resistance8-hydroxyquinolinetriazoleluciferase-basedclick chemistry File: Download Taryn_Ryan_Honors_Thesis.pdf Thesis Supervisors: Kenneth Charles Keiler, Thesis SupervisorDr. Teh-hui Kao, Thesis Honors AdvisorDr. Sarah Ellen Ades, Faculty Reader
4. INVESTIGATION OF THE MOLECULAR TARGETING MECHANISMS OF TRANS-TRANSLATION INHIBITORS AND DETERMINING THE ESSENTIAL NATURE OF TRANS-TRANSLATION IN STAPHYLOCOCCUS AUREUS Open Access Author: Victor, Samjeris Title: INVESTIGATION OF THE MOLECULAR TARGETING MECHANISMS OF TRANS-TRANSLATION INHIBITORS AND DETERMINING THE ESSENTIAL NATURE OF TRANS-TRANSLATION IN STAPHYLOCOCCUS AUREUS Area of Honors: Biochemistry and Molecular Biology Keywords: antibioticstrans-translationBiochemistry and Molecular BiologyS. aureus File: Download SV_Honors_Thesis_2018.pdf Thesis Supervisors: Kenneth Charles Keiler, Thesis SupervisorDr. Wendy Hanna-Rose, Thesis Honors Advisor
5. Identification and Characterization of trans-Translation Inhibitors Open Access Author: Davison, Alexis Title: Identification and Characterization of trans-Translation Inhibitors Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibiotic resistanceribosome profilingKKL-4669high-throughput screenluciferase reporter assaybacterial pathogensCaulobacterin vitro transcription/translation assay File: Download Davison_Alexis_Thesis_Sp2020.pdf Thesis Supervisors: Ken Keiler, Thesis SupervisorYing Gu, Thesis Honors Advisor
6. Looking At Natural Products As Inhibitors Of Ribosome Rescue and Delving Into ArfB Open Access Author: Osterhaus, Emma Title: Looking At Natural Products As Inhibitors Of Ribosome Rescue and Delving Into ArfB Area of Honors: Biochemistry and Molecular Biology Keywords: ribosome rescueantibiotic discoverynatural productstrans-translation File: Download Osterhaus_Final_Thesis_2021.pdf Thesis Supervisors: Kenneth Keiler, Thesis SupervisorJoseph C. Reese, Thesis Honors Advisor
7. New Antibiotics Found in Trans-Translation Pathway Restricted Author: Heilenman, Abigail Title: New Antibiotics Found in Trans-Translation Pathway Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibioticsantibiotic resistanceL27antibiotic targetsL27 ribosomal proteintrans-translation inhibitorsacylaminooxadiazoletetrazoletriazole File: No files available due to restrictions. Thesis Supervisors: Ken Keiler, Thesis SupervisorYing Gu, Thesis Honors Advisor
