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Start Over Area of Honors Biochemistry and Molecular Biology Year 2018

1. THE ROLE OF HEPATOCYTE GROWTH FACTOR IN LONG-TERM RENAL RECOVERY AFTER ACUTE KIDNEY INJURY IN MICE

open_access
Open Access
Author:
Pease, Lauren E
Title:
THE ROLE OF HEPATOCYTE GROWTH FACTOR IN LONG-TERM RENAL RECOVERY AFTER ACUTE KIDNEY INJURY IN MICE
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
renal iri
acute kidney injury
ischemia and reperfusion injury
HGF
cytohesin-2/ARNO
mice
File:
Download Pease_Thesis.pdf
Thesis Supervisors:
Dr. Lorraine C Santy, Thesis Supervisor
Dr. Wendy Hanna-Rose, Thesis Honors Advisor

2. THE EFFECT OF CYTOHESIN-2/ARNO COILED-COIL DOMAIN MUTATIONS ON ITS INTERACTION WITH SCAFFOLD PROTEINS GRASP AND IPCEF

open_access
Open Access
Author:
Marikunte, Sanjana S
Title:
THE EFFECT OF CYTOHESIN-2/ARNO COILED-COIL DOMAIN MUTATIONS ON ITS INTERACTION WITH SCAFFOLD PROTEINS GRASP AND IPCEF
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Cell Migration
HGF Signaling
ARF6
Cytohesin-2/ARNO
GRASP
IPCEF
File:
Download Marikunte_Sanjana_Honors_Thesis.pdf
Thesis Supervisors:
Dr. Lorraine C Santy, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

3. DYSFUNCTION IN THE BIOSYNTHETIC NAD+ SALVAGE PATHWAY AND PURINE BIOSYNTHESIS PATHWAY ALTER NEUROLOGICAL FUNCTION IN CAENORHABDITIS ELEGANS

open_access
Open Access
Author:
Rohan, Laura Elizabeth
Title:
DYSFUNCTION IN THE BIOSYNTHETIC NAD+ SALVAGE PATHWAY AND PURINE BIOSYNTHESIS PATHWAY ALTER NEUROLOGICAL FUNCTION IN CAENORHABDITIS ELEGANS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
C. elegans
Metabolism
Neurological
Purine
Nicotinamide
Model system
File:
Download Rohan_Final_Thesis__1_.pdf
Thesis Supervisors:
Dr. Wendy Hanna-Rose, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor

5. Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors

open_access
Open Access
Author:
Miller, Sydney Alexis
Title:
Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
trans-translation
hydrazine carbonothiols
antibiotic resistance
File:
Download Thesis.pdf
Thesis Supervisors:
Kenneth Charles Keiler, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

7. GENOME-WIDE SCREEN FOR THE INDUCTION OF PHOSPHOETHANOLAMINE AND AMINOARABINOSE MODIFICATIONS ON ESCHERICHIA COLI LIPOPOLYSACCHARIDE

open_access
Open Access
Author:
Smith, Alexander Brock
Title:
GENOME-WIDE SCREEN FOR THE INDUCTION OF PHOSPHOETHANOLAMINE AND AMINOARABINOSE MODIFICATIONS ON ESCHERICHIA COLI LIPOPOLYSACCHARIDE
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Escherichia coli
lipopolysaccharide
phosphoethanolamine
microbiome
transposon sequencing
metabolic endotoxemia
eptA
feoB
File:
Download Smith_Alexander_LPSMod.pdf
Thesis Supervisors:
Timothy Meredith, Thesis Supervisor
Dr. Wendy Hanna-Rose, Thesis Honors Advisor

9. Caernorhabditis elegans model for 16p11.2 recurrent microdeletion suggests differential effects of conserved genes to knockdown

open_access
Open Access
Author:
Thomas, Ayush
Title:
Caernorhabditis elegans model for 16p11.2 recurrent microdeletion suggests differential effects of conserved genes to knockdown
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
C. elegans
16p11.2
Autism
Genetics
File:
Download AT_Thesis_SHC.pdf
Thesis Supervisors:
Dr. Santhosh Girirajan, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

10. The Importance of the Cpx Stress Response Pathway to Mecillinam Resistance in Escherichia Coli

open_access
Open Access
Author:
Sievers, Mary E
Title:
The Importance of the Cpx Stress Response Pathway to Mecillinam Resistance in Escherichia Coli
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Stress Responses
Cpx Stress Response Pathway
Mecillinam
Antibiotic Resistance
B-Lactam Antibiotics
Escherichia Coli
File:
Download Sievers_Thesis.pdf
Thesis Supervisors:
Dr. Sarah Ellen Ades, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor

11. Direct Astrocyte-To-Neuron Conversion in Spinal Neurodegenerative Disease Models

open_access
Open Access
Author:
Keefe, Matthew George
Title:
Direct Astrocyte-To-Neuron Conversion in Spinal Neurodegenerative Disease Models
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
NeuroD1
neurodegenerative disease
spinal cord injury
ALS
neuroscience
transdifferentiation
File:
Download Matthew_Keefe_Honors_Thesis.pdf
Thesis Supervisors:
Dr. Gong Chen, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor

13. Characterization of the Interaction Between S-Locus F-Box Proteins and S-Ribonucleases of Petunia inflata Through the Use of Chimeric S-Locus F-box Proteins and CRISPR/Cas9 Knockout

open_access
Open Access
Author:
Khatri, Wasi Asif
Title:
Characterization of the Interaction Between S-Locus F-Box Proteins and S-Ribonucleases of Petunia inflata Through the Use of Chimeric S-Locus F-box Proteins and CRISPR/Cas9 Knockout
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Petunia inflata
CRISPR/Cas9
Chimeric Proteins
SLF
S-RNase
petunia
self-incompatiblity
s-haplotype
File:
Download Khatri_Wasi_Thesis_3.31.18.pdf
Thesis Supervisors:
Dr. Teh-hui Kao, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Ming Tien, Faculty Reader

14. AN EXAMINATION OF LOCOMOTIVE BEHAVIOR, GERMLINE PROLIFERATION, AND LIPID CONTENT IN A NOVEL AUTISM SPECTRUM DISORDER 16P11.2 DELETION CAENORHABDITIS ELEGANS MODEL

open_access
Open Access
Author:
Sullivan, Rhea Elena
Title:
AN EXAMINATION OF LOCOMOTIVE BEHAVIOR, GERMLINE PROLIFERATION, AND LIPID CONTENT IN A NOVEL AUTISM SPECTRUM DISORDER 16P11.2 DELETION CAENORHABDITIS ELEGANS MODEL
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
neurodevelopmental
disorders
autism
schizophrenia
16p11.2
deletion
Caenorhabditis elegans
intellectual disability
proliferation
obesity
worm
File:
Download Final_Draft_Sullivan.pdf
Thesis Supervisors:
Dr. Santhosh Girirajan, Thesis Supervisor
Dr. Lorraine C Santy, Thesis Honors Advisor

16. Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors

open_access
Open Access
Author:
Ryan, Taryn Jeanne
Title:
Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
trans-translation
antibiotic resistance
8-hydroxyquinoline
triazole
luciferase-based
click chemistry
File:
Download Taryn_Ryan_Honors_Thesis.pdf
Thesis Supervisors:
Kenneth Charles Keiler, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Dr. Sarah Ellen Ades, Faculty Reader

17. INVESTIGATION OF THE MOLECULAR TARGETING MECHANISMS OF TRANS-TRANSLATION INHIBITORS AND DETERMINING THE ESSENTIAL NATURE OF TRANS-TRANSLATION IN STAPHYLOCOCCUS AUREUS

open_access
Open Access
Author:
Victor, Samjeris
Title:
INVESTIGATION OF THE MOLECULAR TARGETING MECHANISMS OF TRANS-TRANSLATION INHIBITORS AND DETERMINING THE ESSENTIAL NATURE OF TRANS-TRANSLATION IN STAPHYLOCOCCUS AUREUS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
antibiotics
trans-translation
Biochemistry and Molecular Biology
S. aureus
File:
Download SV_Honors_Thesis_2018.pdf
Thesis Supervisors:
Kenneth Charles Keiler, Thesis Supervisor
Dr. Wendy Hanna-Rose, Thesis Honors Advisor

18. Mechanisms Underlying the Effects of Edible Mushrooms on Gastrointestinal Health

open_access
Open Access
Author:
Roy, Pratiti
Title:
Mechanisms Underlying the Effects of Edible Mushrooms on Gastrointestinal Health
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Mushrooms
Intestinal gluconeogenesis
gut microbiota
gut-brain neural circuit
File:
Download Pratiti_Roy_Final_Draft.pdf
Thesis Supervisors:
Margherita Teresa-Anna Cantorna, Thesis Supervisor
Ming Tien, Thesis Honors Advisor
Andrew David Patterson, Faculty Reader

19. CONSTRUCTION AND CHARACTERIZATION OF A CYAN FLUORESCENT-EXPRESSING POLIOVIRUS

open_access
Open Access
Author:
Yang, Ziwei
Title:
CONSTRUCTION AND CHARACTERIZATION OF A CYAN FLUORESCENT-EXPRESSING POLIOVIRUS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Virology
Biochemistry
Molecular Biology
Microbiology
Poliovirus
File:
Download Ziwei_Yang_s_Honors_Thesis_Final.pdf
Thesis Supervisors:
Craig Eugene Cameron, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor
Joyce Jose, Faculty Reader

20. STUDY OF NUCLEOSOME DEPLETING FACTORS ON THE STOCHASTIC EXPRESSION OF THE YEAST HO PROMOTER

open_access
Open Access
Author:
O'Callaghan, Jessica
Title:
STUDY OF NUCLEOSOME DEPLETING FACTORS ON THE STOCHASTIC EXPRESSION OF THE YEAST HO PROMOTER
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Chromatin structure
NDRs
NDFs
Transcription regulation
Gene expression
Single-cell fluorescence microscopy
File:
Download Schreyer_Honors_Thesis.pdf
Thesis Supervisors:
Lu Bai, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor