21. An In Vitro Fluid Dynamic Study of a Continuous Flow Device Outlet in Relation to Acquired von Willebrand Syndrome Open Access Author: Lani, Ryan Anthony Title: An In Vitro Fluid Dynamic Study of a Continuous Flow Device Outlet in Relation to Acquired von Willebrand Syndrome Area of Honors: Bioengineering Keywords: laser Doppler velocimetry (LDV)HeartMate IIvon Willebrand factor (vWF)ventricular assist devices (VAD)fluid dynamics File: Download Lani_Ryan_An_In_Vitro_Fluid_Dynamic_Study_of_a_Continuous_Flow_Device.pdf Thesis Supervisors: Dr. Keefe B Manning, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorSteven Deutsch, Faculty Reader
22. Magnetic Resonance Imaging as a Diagnostic Tool in the Detection of Diabetic Retinopathy in Mice Open Access Author: Hobelmann, Kealan Christian Title: Magnetic Resonance Imaging as a Diagnostic Tool in the Detection of Diabetic Retinopathy in Mice Area of Honors: Bioengineering Keywords: MRIdiabetic retinopathydiabetesradiofrequency coilmagnetic resonance imaging File: Download 1-Hobelmann_Kealan_DiabeticRetinopathyMRI.pdf Thesis Supervisors: Thomas Neuberger, Thesis SupervisorPeter J Butler, Thesis Honors Advisor
23. The Role of Nanofiber Architecture in NF-κB Signaling Open Access Author: Hong, Christopher Xighlun Title: The Role of Nanofiber Architecture in NF-κB Signaling Area of Honors: Bioengineering Keywords: NF-κBOPGRANKLRANKMC3T3bonetissue engineeringscaffoldsnanofiberselectrospinningPMMAosteoblastsosteoclasts File: Download Chris_Hong_Thesis_Final_Draft_-_REVISED.pdf Thesis Supervisors: Dr. Justin Lee Brown, Thesis SupervisorPeter J Butler, Thesis Honors Advisor
24. Autocrine Stimulation Of Melanoma Causes Mmp-2 Upregulation And Subsequent Migration Open Access Author: Khristov, Todor R Title: Autocrine Stimulation Of Melanoma Causes Mmp-2 Upregulation And Subsequent Migration Area of Honors: Bioengineering Keywords: melanomatumorextravasationmatrix metalloproteinase File: Download Khristov_Todor_Autocrine.pdf Thesis Supervisors: Cheng Dong, Thesis SupervisorPeter J Butler, Thesis Honors Advisor
25. The Use of Time Correlated Single Photon Counting to Optimize siRNA Encapsulation in Nanoliposomes Open Access Author: Tanella, Elaine Marie Title: The Use of Time Correlated Single Photon Counting to Optimize siRNA Encapsulation in Nanoliposomes Area of Honors: Bioengineering Keywords: siRNAnanoliposomemolecular brightnesstime correlated single photon countingfluorescence correlation spectroscopy File: Download Elaine_Tanella_thesis.pdf Thesis Supervisors: Peter J Butler, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorMargaret June Slattery, Faculty Reader
26. Re-engineering breast cancer metabolism using metformin and dichloroacetate Open Access Author: Banskota, Samagya Title: Re-engineering breast cancer metabolism using metformin and dichloroacetate Area of Honors: Bioengineering Keywords: CancerBreast Cancer MetabolismMetforminDichloroacetate File: Download Thesis_final_.pdf Thesis Supervisors: Dr. Anneke Blackburn, Thesis SupervisorDr. William O Hancock, Thesis SupervisorPeter J Butler, Thesis Honors Advisor
27. Feasibility Studies for Optical Trap Detection of Single Molecule Adhesion and Force Generation Open Access Author: Bernick, David J Title: Feasibility Studies for Optical Trap Detection of Single Molecule Adhesion and Force Generation Area of Honors: Bioengineering Keywords: optical traplaser tweezersintegrin ligand bindingbeadavidinbiotinmicroscopy File: Download Final_Thesis_Bernick_David_Optical_Trap.pdf Thesis Supervisors: Peter J Butler, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorDr. Keefe B Manning, Faculty ReaderDr. William O Hancock, Faculty Reader
28. Quantitative Analysis of Tumor-induced Intracellular Signaling Networks Open Access Author: Weidert, Eric Randall Title: Quantitative Analysis of Tumor-induced Intracellular Signaling Networks Area of Honors: Bioengineering Keywords: melanomaBoolean modelingkinetic modelingE-selectinPAKjunction disassemblycontractility File: Download Weidert_Thesis_Honors.pdf Thesis Supervisors: Cheng Dong, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorReka Z Albert, Faculty Reader
29. Preliminary Study into Visualization Modalities of von Willebrand Proteolysis in Response to Applied Shear Open Access Author: Scanlon, Matthew P Title: Preliminary Study into Visualization Modalities of von Willebrand Proteolysis in Response to Applied Shear Area of Honors: Bioengineering Keywords: von Willebrand FactorvWFproteolysisventricular assist devicecardiovascular diseasevisualizationfluorescence File: Download Scanlon_Thesis.pdf Thesis Supervisors: Dr. Keefe B Manning, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorSteven Deutsch, Faculty Reader
30. Finger Coordination in Neurological Patients Open Access Author: Sallade, Thomas Douglas Title: Finger Coordination in Neurological Patients Area of Honors: Bioengineering Keywords: Olivopontocerebellar atrophyMaximum Voluntary ContractionEnslavingSynergyFinger Coordination File: Download Sallade_FingerCoordNeuroPatient_EFinal_NS.pdf Thesis Supervisors: Mark Latash, Thesis SupervisorPeter J Butler, Thesis Honors Advisor
31. Proximity Ligation for Protein Detection and Protein-compound Interaction Open Access Author: Mccaffrey, Jennifer Lauren Title: Proximity Ligation for Protein Detection and Protein-compound Interaction Area of Honors: Bioengineering Keywords: proximity ligationencoded library technologyprotein-compound interaction File: Download McCaffrey_J_Thesis_SP2012.pdf Thesis Supervisors: Dr. William O Hancock, Thesis SupervisorPeter J Butler, Thesis Honors Advisor
32. A correlative study of fluid mechanics and evidence of thrombus formation within the Penn State 50 cc V-2 left ventricular assist device Open Access Author: Topper, Stephen Robert Title: A correlative study of fluid mechanics and evidence of thrombus formation within the Penn State 50 cc V-2 left ventricular assist device Area of Honors: Bioengineering Keywords: ventricular assist devicethrombosisfluid dynamicspulsatilewall shearsurface evaluationparticle image velocimetry File: Download Topper_Stephen_Schreyer_Honors_Thesis_2012.pdf Thesis Supervisors: Dr. Keefe B Manning, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorSteven Deutsch, Faculty Reader
33. Design By Example: a Web-based Tool for Context-driven Design of Biomedical Devices Open Access Author: Dzombak, Rachel Victoria Title: Design By Example: a Web-based Tool for Context-driven Design of Biomedical Devices Area of Honors: Bioengineering Keywords: medical devicesdeveloping countriescontextdesignbioengineeringafricaKenya File: Download Dzombak_Rachel_DesignByExample_Final.pdf Thesis Supervisors: Peter J Butler, Thesis Honors AdvisorPeter J Butler, Thesis SupervisorKhanjan Mehta, Faculty ReaderMargaret June Slattery, Faculty Reader
34. Finite Element Analysis of Microfabricated Poly(Glycerol Sebacate) Scaffolds for use in Heart Valve Tissue Engineering Open Access Author: Chowdhury, Surjyanil Title: Finite Element Analysis of Microfabricated Poly(Glycerol Sebacate) Scaffolds for use in Heart Valve Tissue Engineering Area of Honors: Bioengineering Keywords: Chowdhuryfinite elementCOMSOLheart valvetissue engineeringpoly glycerol sebacatePGSmicrofabricatescaffoldmesh File: Download honors_thesis_final_draft.pdf Thesis Supervisors: Dr. William O Hancock, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorDr. Keefe B Manning, Faculty Reader
35. Independent On-line Information Processing in Bimanual Coordinated Movements Open Access Author: Waltz, Lauren Ann Title: Independent On-line Information Processing in Bimanual Coordinated Movements Area of Honors: Bioengineering Keywords: motor controlbimanual coordination File: Download Waltz_Lauren_IndependentOnLineInformationProcessing.pdf Thesis Supervisors: Robert L Sainburg, Thesis SupervisorAndrzej Przybyla, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorStephen Jacob Piazza, Faculty Reader
36. The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs) Open Access Author: Sheldrake, Anne E Title: The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs) Area of Honors: Bioengineering Keywords: MEFstissue engineeringcardiacacrylamidebisacrylamideheartfibrillinscar tissue File: Download sheldrake_anne_effect_of_susbstrate_stiffness.pdf Thesis Supervisors: Dr. Justin Lee Brown, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorDr. William O Hancock, Faculty Reader
37. Nanofiber Curvature Sensing Through an Arfaptin and Rac1 Dependent Mechanism Open Access Author: Higgins, Andrew Michael Title: Nanofiber Curvature Sensing Through an Arfaptin and Rac1 Dependent Mechanism Area of Honors: Bioengineering Keywords: nanofibersRac1arfaptincurvature sensing File: Download Higgins_Andrew_NanofiberCurvatureSensing-Honors.pdf Thesis Supervisors: Dr. Justin Lee Brown, Thesis SupervisorDr. William O Hancock, Thesis Honors AdvisorPeter J Butler, Faculty Reader
38. Fluid Dynamic Study of a Compliant Model for an Inferior Vena Cava Filter Open Access Author: Fox, Evan M Title: Fluid Dynamic Study of a Compliant Model for an Inferior Vena Cava Filter Area of Honors: Bioengineering Keywords: deep vein thrombosispulmonary embolisminferior vena cava filterparticle image velocimetry File: Download Fox_Thesis_Honors_04_12.pdf Thesis Supervisors: Dr. Keefe B Manning, Thesis SupervisorPeter J Butler, Thesis Honors AdvisorDr. William O Hancock, Faculty Reader
39. Multiscale Modeling of Cancer Cell Adhesion Open Access Author: Behr, Julie Marie Title: Multiscale Modeling of Cancer Cell Adhesion Area of Honors: Bioengineering Keywords: cellular adhesioncomputational fluid dynamicsbinding affinitymelanomacancer cells File: Download 1-JulieBehr-HonorsThesis.pdf Thesis Supervisors: Cheng Dong, Thesis SupervisorRobert Francis Kunz, Thesis SupervisorDr. William O Hancock, Thesis Honors Advisor
40. The Effects of Hematocrit and Rotation Time on Platelet Adhesion to a Polyurethane Urea Surface Open Access Author: Grunenwald, Lauren Elizabeth Title: The Effects of Hematocrit and Rotation Time on Platelet Adhesion to a Polyurethane Urea Surface Area of Honors: Bioengineering Keywords: platelet adhesionrotating diskpolyurethane urea File: Download LaurenGrunenwaldThesis-HonorsFinal.pdf Thesis Supervisors: Dr. Keefe B Manning, Thesis SupervisorDr. Keefe B Manning, Thesis Honors AdvisorMargaret June Slattery, Faculty ReaderChristopher Alan Siedlecki, Faculty Reader