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101. THE DIFFERENTIAL EFFECTS OF ALL-TRANS RETINOIC ACID ON RETINOIC ACID RECEPTOR (RAR)- AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-β/δ (PPARβ/δ)-DEPENDENT SIGNALING IN THE HUMAN NT2/D1 TESTICULAR EMBRYONAL CANCER CELL LINE

open_access
Open Access
Author:
Dobrzanski, Tomasz Pawel
Title:
THE DIFFERENTIAL EFFECTS OF ALL-TRANS RETINOIC ACID ON RETINOIC ACID RECEPTOR (RAR)- AND PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-β/δ (PPARβ/δ)-DEPENDENT SIGNALING IN THE HUMAN NT2/D1 TESTICULAR EMBRYONAL CANCER CELL LINE
Area of Honors:
Biology
Keywords:
testicular cancer
embryonal carcinoma
all-trans retinoic acid (atRA)
Peroxisome proliferator activated receptor-β/δ (PPARβ/δ)
File:
Download Thesis_Final2.pdf
Thesis Supervisors:
Jeffrey Maurice Peters, Thesis Supervisor
Katriona Shea, Thesis Honors Advisor

102. PP2A-PR72: Interactions with β[Heavy]-Spectrin and Investigation of Roles in Apical Polarity and Endosomal Trafficking

open_access
Open Access
Author:
Travor, Mark D
Title:
PP2A-PR72: Interactions with β[Heavy]-Spectrin and Investigation of Roles in Apical Polarity and Endosomal Trafficking
Area of Honors:
Biology
Keywords:
Actin
Cytoskeleton
Drosophila
Spectrin
PP2A
File:
Download Travor_Mark_PP2A_and_BetaH_Roles_in_Endosomal_Trafficking_and_Polarity.pdf
Thesis Supervisors:
Graham Hugh Thomas, Thesis Supervisor
Dr. Michael Axtell, Thesis Honors Advisor

103. Spatial distribution by size and age and allometric relationships of a spruce population in west Greenland

open_access
Open Access
Author:
Mistrick, Janine
Title:
Spatial distribution by size and age and allometric relationships of a spruce population in west Greenland
Area of Honors:
Biology
Keywords:
Picea glauca
P. glauca
Kangerlussuaq
Greenland
climate change
ecology
Arctic
spruce
white spruce
novel ecosystem
File:
Download MISTRICK_Thesis_Final.pdf
Thesis Supervisors:
Eric S Post, Thesis Supervisor
Dr. James Harold Marden, Thesis Honors Advisor

104. Interactions of Hsp23, FoxO, and ESCRTIII-Vps24 in Mediating Proteostasis in Drosophila melanogaster Flight Motor Cells

open_access
Open Access
Author:
Fatima, Shahroz
Title:
Interactions of Hsp23, FoxO, and ESCRTIII-Vps24 in Mediating Proteostasis in Drosophila melanogaster Flight Motor Cells
Area of Honors:
Biology
Keywords:
Drosophila melanogaster
neurodegeneration
proteostasis
heat shock
Hsp23
FoxO
ESCRTIII
Vps24
autophagy
proteasome
File:
Download Fatima_Shahroz_Final_Thesis.pdf
Thesis Supervisors:
Fumiko Kawasaki, Thesis Supervisor
Katriona Shea, Thesis Honors Advisor

106. Diversity of Short Sequences Among Genomes of Inversion Strains in Drosophila Pseudoobscura

open_access
Open Access
Author:
Lee, Megan E
Title:
Diversity of Short Sequences Among Genomes of Inversion Strains in Drosophila Pseudoobscura
Area of Honors:
Biology
Keywords:
Drosophila Pseudoobscura
Drosophila
inversion strains
short sequences
repeats
inversion
cline
polymorphic
motifs
File:
Download Lee_Megan_DiversityofShortSequencesofDrosophilaPseudoobscura.pdf
Thesis Supervisors:
Dr. Stephen Wade Schaeffer, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor

107. The origin and evolution of inversion breakpoint sequences on the third chromosome of Drosophila pseudoobscura

open_access
Open Access
Author:
Randolph, Haley Elizabeth
Title:
The origin and evolution of inversion breakpoint sequences on the third chromosome of Drosophila pseudoobscura
Area of Honors:
Biology
Keywords:
chromosomal rearrangement
breakpoint sequence evolution
inversion mutation
paracentric inversion
Drosophila pseudoobscura
File:
Download HER_thesis_final.pdf
Thesis Supervisors:
Dr. Stephen Wade Schaeffer, Thesis Supervisor
Dr. James Harold Marden, Thesis Honors Advisor

108. Population genomic assessments of the plausibility of evolutionary ecology hypotheses for human rainforest hunter-gatherers

open_access
Open Access
Author:
Cohen, Jacob Aubrey
Title:
Population genomic assessments of the plausibility of evolutionary ecology hypotheses for human rainforest hunter-gatherers
Area of Honors:
Biology
Keywords:
rainforest hunter-gatherer
pygmy phenotype
convergent evolution
polygenic adaptation
ecology
File:
Download Jacob_Cohen_Final_Thesis_Format_Edits.pdf
Thesis Supervisors:
George H Perry, Thesis Supervisor
Katriona Shea, Thesis Honors Advisor

113. Characterization of Neutral Sphingomyelinase in Plasma and PBMCs and the Role of Sphingolipid Enzymes in Pathology.

open_access
Open Access
Author:
Dobson, Jennifer Lauren
Title:
Characterization of Neutral Sphingomyelinase in Plasma and PBMCs and the Role of Sphingolipid Enzymes in Pathology.
Area of Honors:
Biology
Keywords:
Sphingolipid enzymes
sphingolipid pathway
neutral sphingomyelinase
Neurodegenerative diseases
psychiatric disorders
File:
Download 2016_04_06_Jenny_Thesis_FINAL_4_11.pdf
Thesis Supervisors:
Dr. Stephen Wade Schaeffer, Thesis Supervisor
Richard Cyr, Thesis Honors Advisor

114. The differential effects of all-trans retinoic acid on retinoic acid receptor (RAR) and peroxisome proliferator-activated receptor (PPARβ/δ)-dependent signaling in the human NGP neuroblastoma cancer cell line.

open_access
Open Access
Author:
Krevitz, Jacqueline Anne
Title:
The differential effects of all-trans retinoic acid on retinoic acid receptor (RAR) and peroxisome proliferator-activated receptor (PPARβ/δ)-dependent signaling in the human NGP neuroblastoma cancer cell line.
Area of Honors:
Biology
Keywords:
PPAR
neuroblastoma
ngp
retinoic acid
atra
rar
cancer
File:
Download Jacqueline_Krevitz_final_thesis.pdf
Thesis Supervisors:
Jeffrey Maurice Peters, Thesis Supervisor
Dr. Stephen Wade Schaeffer, Thesis Honors Advisor

116. Analyzing factors for out-planting strategies of Acropora cervicornis genotypes residing in nurseries

open_access
Open Access
Author:
Weinheimer, Alaina Rose
Title:
Analyzing factors for out-planting strategies of Acropora cervicornis genotypes residing in nurseries
Area of Honors:
Biology
Keywords:
coral
ocean acidification
compatibility
molecular ecology
coral restoration
File:
Download Weinheimer_Alaina_thesis_final_copy_spring_2016.pdf
Thesis Supervisors:
Iliana Brigitta Baums, Thesis Supervisor
Dr. Michael Axtell, Thesis Honors Advisor

119. The Impact of Co-Infections with Medium and High Virus Virulence on the Length and Fecundity of Trichostrongylus retortaeformis

open_access
Open Access
Author:
Hake, Emily A
Title:
The Impact of Co-Infections with Medium and High Virus Virulence on the Length and Fecundity of Trichostrongylus retortaeformis
Area of Honors:
Biology
Keywords:
myxoma
helminth
co-infection
virulence
File:
Download Hake_Emily_thesis_final.pdf
Thesis Supervisors:
Isabella Cattadori, Thesis Supervisor
Dr. Stephen Wade Schaeffer, Thesis Honors Advisor

120. The Effect of Selected Transcription Factors on Inhibiting In Vitro And In Vivo Hepatocellular Carcinoma Development

open_access
Open Access
Author:
Lin, John Lizhong
Title:
The Effect of Selected Transcription Factors on Inhibiting In Vitro And In Vivo Hepatocellular Carcinoma Development
Area of Honors:
Biology
Keywords:
liver cancer
HCC
Hepatocellular Carcinoma
HepG2
Hep3B
AFP
Ki67
Gene Therapy
Viral Infection
Transfection
Cancer Treatment
File:
Download Lin_John_Liver_Cancer_Therapy.pdf
Thesis Supervisors:
Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

122. NOVEL 3-DIMENSIONAL ELECTRON MICROSCOPIC ANALYSIS OF MITOCHONDRIAL MORPHOLOGY IN AGED AND ISCHEMIC FEMALE RAT HEART

open_access
Open Access
Author:
Henry, Jessica Behin
Title:
NOVEL 3-DIMENSIONAL ELECTRON MICROSCOPIC ANALYSIS OF MITOCHONDRIAL MORPHOLOGY IN AGED AND ISCHEMIC FEMALE RAT HEART
Area of Honors:
Biology
Keywords:
ischemic injury
mitochondria
aging
menopause
heart
File:
Download Henry_Jessica_Thesis.pdf
Thesis Supervisors:
Dr. Donna Hope Korzick, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

124. Development of a R package for Classifying Duplicate Gene Retention Mechanisms (CDROM) and Application to Duplicate Genes in Grasses

open_access
Open Access
Author:
Perry, Brent R
Title:
Development of a R package for Classifying Duplicate Gene Retention Mechanisms (CDROM) and Application to Duplicate Genes in Grasses
Area of Honors:
Biology
Keywords:
Gene duplication
subfunctionalization
grasses
Oryza sativa
Sorghum bicolor
Brachypodium distachyon
neofunctionalization
specialization
conservation
CDROM
File:
Download Perry_Brent_Thesis.pdf
Thesis Supervisors:
Raquel Assis, Thesis Supervisor
Timothy J Jegla, Thesis Honors Advisor

125. Impact of drug dose and treatment time on the synergism between pyrimethamine and sulfadoxine in the mouse malaria model

open_access
Open Access
Author:
Lai, Michelle Song
Title:
Impact of drug dose and treatment time on the synergism between pyrimethamine and sulfadoxine in the mouse malaria model
Area of Honors:
Biology
Keywords:
drug resistance
malaria
pyrimethamine
sulfadoxine
treatment timing
drug dose
combination therapy
File:
Download Michelle_Lai_Honors_Thesis_-_Impact_of_drug_dose_and_treatment_time_on_the_synergism_between_pyrimethamine_and_sulfadoxine_in_the_mouse_malaria_model.pdf
Thesis Supervisors:
Andrew Fraser Read, Thesis Supervisor
Sarah Mary Assmann, Thesis Honors Advisor

126. THE IMPACT OF ENDOGENOUS RETROVIRUS S2220 ON MULE DEER ISY1 GENE EXPRESSION

open_access
Open Access
Author:
Bogale, Kaleb Tadesse
Title:
THE IMPACT OF ENDOGENOUS RETROVIRUS S2220 ON MULE DEER ISY1 GENE EXPRESSION
Area of Honors:
Biology
Keywords:
Endogenous retrovirus
ERV
LTR
long terminal repeat
solo LTR
solo long terminal repeat
gene expression
mule deer
Odocoileus hemionus
RNA
Splicing
retrovirus
pre-mrna splicing gene
ISY1 gene
isy1
gene regulation
hardy-weinberg equilibrium
population genetics
Bos taurus
domestic cow
Ovis aris
sheep
File:
Download KalebBogale_ThesisFinal.pdf
Thesis Supervisors:
Dr. Mary Poss, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

131. Examining Software Efficacy In Identifying Candidiate Copy Number Variant Regions Implicating Neurodevelopmental Phenotypes Using Next Generation Sequencing Technology

open_access
Open Access
Author:
Kelkar, Neil
Title:
Examining Software Efficacy In Identifying Candidiate Copy Number Variant Regions Implicating Neurodevelopmental Phenotypes Using Next Generation Sequencing Technology
Area of Honors:
Biology
Keywords:
CNV
exome
wes
caller
xhmm
clamms
codex
conifer
canoes
human disease
whole exome sequencing
File:
Download Neil_Kelkar_thesis.pdf
Thesis Supervisors:
Dr. Santhosh Girirajan, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor

133. A Phylogenetic Meta-Analysis Of Human-Specific Parasites And Diseases To Elucidate Patterns Of Diversity and Evolution

open_access
Open Access
Author:
Battaglia, Angela Teresa
Title:
A Phylogenetic Meta-Analysis Of Human-Specific Parasites And Diseases To Elucidate Patterns Of Diversity and Evolution
Area of Honors:
Biology
Keywords:
parasite
phylogenetic
evolution
human migration
File:
Download Angela_Battaglia_thesis_final.pdf
Thesis Supervisors:
George H Perry, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

135. Elucidating the Interactions Between Chronic High-Fat Diet Treatment and GABAergic Inhibition in the Emotional Behavior of Mice

open_access
Open Access
Author:
Patel, Akshilkumar Navindrabhai
Title:
Elucidating the Interactions Between Chronic High-Fat Diet Treatment and GABAergic Inhibition in the Emotional Behavior of Mice
Area of Honors:
Biology
Keywords:
High-Fat Diet
GABAergic Inhibition
Excitation:Inhibition Ratio
Anxiety
Depression
Mouse Behavior
Inflammation
Diet-Induced Obesity
γ2+/- mutant mouse model
SSTCre:γ2f/f mutant mouse model
File:
Download Patel_Akshilkumar_HFD_GABAergic_inhibition_Final_Thesis.pdf
Thesis Supervisors:
Dr. Bernhard Lüscher, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor

137. ASSESSMENT OF THE SERUM PREGNANCY-SPECIFIC PROTEIN B TEST TO DETERMINE PREGNANCY IN FREE-RANGING ELK (Cervus elaphus)

open_access
Open Access
Author:
Silva Seixas, Julia
Title:
ASSESSMENT OF THE SERUM PREGNANCY-SPECIFIC PROTEIN B TEST TO DETERMINE PREGNANCY IN FREE-RANGING ELK (Cervus elaphus)
Area of Honors:
Biology
Keywords:
Elk
Pregnancy
Pregnancy-specific protein B
PSPB
ELISA
Post-mortem
Uterine examination
Accuracy
File:
Download JuliaSilvaSeixas_Undergraduate_HonorsThesis.pdf
Thesis Supervisors:
Jenny Suzanne Fisher, Thesis Supervisor
Benoit A Dayrat, Thesis Honors Advisor
Justin D Brown, Faculty Reader

138. SPECIES DELIMITATION AND THE EVOLUTION OF HIGHLY VARIABLE MORPHOLOGICAL TRAITS IN THE HOLARCTIC SOCIALLY PARASITIC BUMBLEBEE, BOMBUS FLAVIDUS

open_access
Open Access
Author:
Williams, Sarah Danielle
Title:
SPECIES DELIMITATION AND THE EVOLUTION OF HIGHLY VARIABLE MORPHOLOGICAL TRAITS IN THE HOLARCTIC SOCIALLY PARASITIC BUMBLEBEE, BOMBUS FLAVIDUS
Area of Honors:
Biology
Keywords:
bombus flavidus
coi
species delimitation
psithyrus
bombus fernaldae
File:
Download Williams_Sarah_Thesis_Final.pdf
Thesis Supervisors:
Heather M Hines, Thesis Supervisor
Dr. James Harold Marden, Thesis Honors Advisor

139. INNATE FEAR MODELING THROUGH PREDATOR ODOR EXPOSURE IN AWAKE RODENTS – AN FMRI STUDY

open_access
Open Access
Author:
Messner, Christopher K
Title:
INNATE FEAR MODELING THROUGH PREDATOR ODOR EXPOSURE IN AWAKE RODENTS – AN FMRI STUDY
Area of Honors:
Biology
Keywords:
Functional Magnetic Resonance Imaging
Neuroscience
Stress
Innate Fear
Odor Exposure
File:
Download Final_Schreyer_Thesis__2__Correct.pdf
Thesis Supervisors:
Dr. Nanyin Zhang, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor
Dr. Yingwei Mao, Faculty Reader

144. DIRECT ASTROCYTE TO NEURON REPROGRAMMING FOR FUNCTIONAL REPAIR IN INTRACRANIAL HEMORRHAGE MOUSE MODEL

open_access
Open Access
Author:
Huang, Pengqian
Title:
DIRECT ASTROCYTE TO NEURON REPROGRAMMING FOR FUNCTIONAL REPAIR IN INTRACRANIAL HEMORRHAGE MOUSE MODEL
Area of Honors:
Biology
Keywords:
ICH
collagenase
stroke
neuronal loss
direct conversion
NeuroD1
Hippocampus
Striatum
astrocytes
neuronal recovery
File:
Download Final_thesis.pdf
Thesis Supervisors:
Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

148. BINDING AFFINITIES OF FLAVINS TO RIBOFLAVIN BINDING PROTEIN USING FLUORESCENCE SPECTROMETRY AND ISOTHERMAL TITRATION CALORIMETRY, AND ESTIMATED BINDING ENERGIES USING COMPUTATIONAL APPROACHES

open_access
Open Access
Author:
Yazgi, Habib A
Title:
BINDING AFFINITIES OF FLAVINS TO RIBOFLAVIN BINDING PROTEIN USING FLUORESCENCE SPECTROMETRY AND ISOTHERMAL TITRATION CALORIMETRY, AND ESTIMATED BINDING ENERGIES USING COMPUTATIONAL APPROACHES
Area of Honors:
Biology
Keywords:
Riboflavin binding protein
Riboflavin
Cancer
Folate receptor alpha
Binding energy
Binding affinity
Isothermal Titration Calorimetry
Fluorescence Spectroscopy
ICM-Pro
File:
Download Yazgi_Habib_Riboflavin_Binding_Protein.pdf
Thesis Supervisors:
Julie B Ealy, Thesis Supervisor
Dr. Sandy Feinstein, Thesis Honors Advisor

149. Genetic Analysis of Protection from Environmental Stress-Induced Degeneration: Characterization of a Loss of Function Drosophila Mutant for the Cytoplasmic RNA Exosome Component, dSKI2

open_access
Open Access
Author:
Moon, Mackenzie Taylor
Title:
Genetic Analysis of Protection from Environmental Stress-Induced Degeneration: Characterization of a Loss of Function Drosophila Mutant for the Cytoplasmic RNA Exosome Component, dSKI2
Area of Honors:
Biology
Keywords:
Drosophila melanogaster
neurodegeneration
heat shock
pele
SKI2
Ski complex
infertility
File:
Download Moon_Mackenzie_Thesis_Final.pdf
Thesis Supervisors:
Richard W Ordway, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor
Dr. Stephen Wade Schaeffer, Faculty Reader

150. INVESTIGATING THE LARVAL COMPETITIVE ABILITIES OF DIFFERENT CHROMOSOMAL INVERSION PATTERNS WITHIN DROSOPHILA PSEUDOOBSCURA

open_access
Open Access
Author:
Kutz, David James
Title:
INVESTIGATING THE LARVAL COMPETITIVE ABILITIES OF DIFFERENT CHROMOSOMAL INVERSION PATTERNS WITHIN DROSOPHILA PSEUDOOBSCURA
Area of Honors:
Biology
Keywords:
Inversion
polymorphism
heterogeneous environment
competitive ability
competition
File:
Download Kutz_Thesis_final.pdf
Thesis Supervisors:
Dr. Stephen Wade Schaeffer, Thesis Supervisor
Dr. Michael Axtell, Thesis Honors Advisor