1. Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors Open Access Author: Miller, Sydney Alexis Title: Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationhydrazine carbonothiolsantibiotic resistance File: Download Thesis.pdf Thesis Supervisors: Kenneth Charles Keiler, Thesis SupervisorDavid Scott Gilmour, Thesis Honors Advisor
2. Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors Open Access Author: Ryan, Taryn Jeanne Title: Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibiotic resistance8-hydroxyquinolinetriazoleluciferase-basedclick chemistry File: Download Taryn_Ryan_Honors_Thesis.pdf Thesis Supervisors: Kenneth Charles Keiler, Thesis SupervisorDr. Teh-hui Kao, Thesis Honors AdvisorDr. Sarah Ellen Ades, Faculty Reader
3. Identification and Characterization of trans-Translation Inhibitors Open Access Author: Davison, Alexis Title: Identification and Characterization of trans-Translation Inhibitors Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibiotic resistanceribosome profilingKKL-4669high-throughput screenluciferase reporter assaybacterial pathogensCaulobacterin vitro transcription/translation assay File: Download Davison_Alexis_Thesis_Sp2020.pdf Thesis Supervisors: Ken Keiler, Thesis SupervisorYing Gu, Thesis Honors Advisor
4. New Antibiotics Found in Trans-Translation Pathway Restricted Author: Heilenman, Abigail Title: New Antibiotics Found in Trans-Translation Pathway Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibioticsantibiotic resistanceL27antibiotic targetsL27 ribosomal proteintrans-translation inhibitorsacylaminooxadiazoletetrazoletriazole File: No files available due to restrictions. Thesis Supervisors: Ken Keiler, Thesis SupervisorYing Gu, Thesis Honors Advisor