1. In Vitro Examination and Detection of a Triplex Structure Produced as a Result of a GAA Trinucleotide Repeat Sequence in Patients with Friedreich's Ataxia Open Access Author: Pettoruto, Zachary Title: In Vitro Examination and Detection of a Triplex Structure Produced as a Result of a GAA Trinucleotide Repeat Sequence in Patients with Friedreich's Ataxia Area of Honors: Biochemistry and Molecular Biology Keywords: Friedreich's AtaxiaTriplexTriplex StructureTrinucleotide RepeatGAAIn vitroMicrosatelliteChemical Modification File: Download Zack_Pettoruto_-_Schreyer_Honors_College_Thesis_Final_Submission_2020.pdf Thesis Supervisors: Maria Krasilnikova, Thesis SupervisorMing Tien, Thesis Honors Advisor
2. The Biophysical and Biochemical Characterization of the Transcription of Mitochondrial DNA Open Access Author: Oliver, Gwen Title: The Biophysical and Biochemical Characterization of the Transcription of Mitochondrial DNA Area of Honors: Biochemistry and Molecular Biology Keywords: transcriptionTFAMmitochondriamtDNA File: Download Guinevere_Oliver_Thesis.pdf Thesis Supervisors: Craig Cameron, Thesis SupervisorJoseph C. Reese, Thesis Honors Advisor
3. Exploring The Interaction Between Colicin B And The TonB Dependent Transporter FepA Using Colicin B Mutants Open Access Author: Bhimwal, Rijul Title: Exploring The Interaction Between Colicin B And The TonB Dependent Transporter FepA Using Colicin B Mutants Area of Honors: Biochemistry and Molecular Biology Keywords: TonBColicin BFepAOuter MembraneBacteriocinEscherichia coliGram-negative File: Download Rijul_Bhimwal_Honors_Thesis.pdf Thesis Supervisors: Kathleen Postle, Thesis SupervisorDavid Scott Gilmour, Thesis Honors Advisor
4. Characterization of a novel neuronal injury model with Drosophila Open Access Author: Vora, Aabha Title: Characterization of a novel neuronal injury model with Drosophila Area of Honors: Biochemistry and Molecular Biology Keywords: Drosophilaneuronmicrotubuleseberlybiochemistryinjuryneurodegenerative diseasemicroscopycell biologygeneticsfruit fly File: Download Thesis042820.pdf Thesis Supervisors: Melissa Rolls, Thesis SupervisorDavid Scott Gilmour, Thesis Honors Advisor
5. Role of the Aryl Hydrocarbon Receptor on Enteric Neuron Structure and Function Open Access Author: Brosius, Daniel Title: Role of the Aryl Hydrocarbon Receptor on Enteric Neuron Structure and Function Area of Honors: Biochemistry and Molecular Biology Keywords: Aryl Hydrocarbon ReceptorAHRTCDDMelatoninENSCyp1a1nNOS File: Download thesis_DanielBrosius.pdf Thesis Supervisors: Andrew David Patterson, Thesis SupervisorSanthosh Girirajan, Thesis Honors Advisor
6. CsrA-Mediated Activation of ymdA Translation Open Access Author: Poly, Stephanie Title: CsrA-Mediated Activation of ymdA Translation Area of Honors: Biochemistry and Molecular Biology Keywords: CsrAymdAgene expressiontranslational activation File: Download POLY_S_2020_Thesis_Final_.pdf Thesis Supervisors: Paul Babitzke, Thesis SupervisorMing Tien, Thesis Honors Advisor
7. Structural analysis and characterization of novel class Id ribonucleotide reductases Open Access Author: Gandhi, Avani Title: Structural analysis and characterization of novel class Id ribonucleotide reductases Area of Honors: Biochemistry and Molecular Biology Keywords: ribonucleotide reductaseDNA repairX-ray crystallographymetallocofactor File: Download Avani_Gandhi_SHC_Final_Thesis.pdf Thesis Supervisors: Amie Kathleen Boal, Thesis SupervisorTeh-Hui Kao, Thesis Honors Advisor
8. Diffusion of Bacterial Quorum Sensing Molecules within the Squid Light Organ Open Access Author: Yount, Taylor Title: Diffusion of Bacterial Quorum Sensing Molecules within the Squid Light Organ Area of Honors: Biochemistry and Molecular Biology Keywords: Quorum SensingHost-Microbe SymbiosisStrain DiversityBacteriaVibrio fischeriSquidEuprymna scolopesBioluminescence File: Download Taylor_Yount_Thesis.pdf Thesis Supervisors: Timothy Iwao Miyashiro, Thesis SupervisorSanthosh Girirajan, Thesis Honors Advisor
9. Quinoline-based Small Molecules Inhibit the ClpP Protease in Bacterial Cells Open Access Author: Brogan, Anna Pauline Title: Quinoline-based Small Molecules Inhibit the ClpP Protease in Bacterial Cells Area of Honors: Biochemistry and Molecular Biology Keywords: microbiologybiochemistrysmall moleculesClpPquinolineschemical biology File: Download thesis_final_draft_w_shc_edits__4-21-20_.pdf Thesis Supervisors: Ken Keiler, Thesis SupervisorPaul Babitzke, Thesis Honors Advisor
10. Investigating the Role of FakA and FakB in Lipoprotein Biosynthesis in Staphylococcus aureus Open Access Author: Hussain, Sheherbano Title: Investigating the Role of FakA and FakB in Lipoprotein Biosynthesis in Staphylococcus aureus Area of Honors: Biochemistry and Molecular Biology Keywords: lipoproteinsFakAFakBstaphylococcus aureusTLR activityacylationTLR2/1TLR2/6fatty acids File: Download hussain_sheherbano.pdf Thesis Supervisors: Timothy Charles Meredith, Thesis SupervisorSanthosh Girirajan, Thesis Honors Advisor
11. Random Forest Classification in Copy Number Variation Discovery Open Access Author: Jayakar, Gopal Title: Random Forest Classification in Copy Number Variation Discovery Area of Honors: Biochemistry and Molecular Biology Keywords: CNVMachine LearningSequencingGenomicsBioinformaticsRandom Forest File: Download Thesis_Jayakar.pdf Thesis Supervisors: Santhosh Girirajan, Thesis SupervisorSanthosh Girirajan, Thesis Honors AdvisorShaun Mahony, Faculty Reader
12. Identification and Characterization of trans-Translation Inhibitors Open Access Author: Davison, Alexis Title: Identification and Characterization of trans-Translation Inhibitors Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibiotic resistanceribosome profilingKKL-4669high-throughput screenluciferase reporter assaybacterial pathogensCaulobacterin vitro transcription/translation assay File: Download Davison_Alexis_Thesis_Sp2020.pdf Thesis Supervisors: Ken Keiler, Thesis SupervisorYing Gu, Thesis Honors Advisor
13. Generation of Chimeric Zika Viruses To Study Capsid Specificity and Assembly Process Open Access Author: Liu, Xinyi Title: Generation of Chimeric Zika Viruses To Study Capsid Specificity and Assembly Process Area of Honors: Biochemistry and Molecular Biology Keywords: ZikaFlavivirusCapsidComplement File: Download Undergraduate_Thesis.pdf Thesis Supervisors: Joyce Jose, Thesis SupervisorPaul Babitzke, Thesis Honors Advisor
14. Designing Optimized Protein Molecular Weight Markers Applicable to both Coomassie Staining and Western Blotting Open Access Author: Shibata, Yoshitaka Joey Title: Designing Optimized Protein Molecular Weight Markers Applicable to both Coomassie Staining and Western Blotting Area of Honors: Biochemistry and Molecular Biology Keywords: protein molecular weight markersSDS-PAGEWestern blottingIgG antibody bindingpolycistronic expressionprotein expressionprotein purification File: Download Shibata_Thesis_DesigningOptimizedProteinMWMarkers.pdf Thesis Supervisors: Song Tan, Thesis SupervisorWendy Hanna-Rose, Thesis Honors Advisor
15. Functional characterization of an ApiAP2 transcription factor in sexual development of Plasmodium falciparum Open Access Author: Suhendra, Michelle Title: Functional characterization of an ApiAP2 transcription factor in sexual development of Plasmodium falciparum Area of Honors: Biochemistry and Molecular Biology Keywords: malariagene regulationtranscriptiontranscription regulationfalciparumplasmodiumapiap2 File: Download Suhendra-thesis-final.pdf Thesis Supervisors: Manuel Llinas, Thesis SupervisorPaul Babitzke, Thesis Honors Advisor
16. A mechanistic investigation of lipoyl synthase from Escherichia coli and Staphylococcus aureus Open Access Author: Rankin, Ananda Title: A mechanistic investigation of lipoyl synthase from Escherichia coli and Staphylococcus aureus Area of Honors: Biochemistry and Molecular Biology Keywords: LipALipoic AcidIron-Sulfur ClusterRadical SAM Enzyme File: Download Rankin_Thesis_Final.pdf Thesis Supervisors: Squire J Booker, Thesis SupervisorPaul Babitzke, Thesis Honors Advisor
17. Investigation of the Role of Gene SA1798 in S. aureus Open Access Author: Cole, Kaitlin Title: Investigation of the Role of Gene SA1798 in S. aureus Area of Honors: Biochemistry and Molecular Biology Keywords: Staphylococcus aureustunicamycinantibiotic resistanceSA1798SA618 File: Download Kaitlin_Cole_Final_Thesis.pdf Thesis Supervisors: Timothy Charles Meredith, Thesis SupervisorMing Tien, Thesis Honors Advisor