Search

Author:

Miller, Sydney Alexis

Title:

Characterization and Target Identification of Hydrazine carbonothiols, a class of trans-Translation Inhibitors

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

trans-translation
hydrazine carbonothiols
antibiotic resistance

File:

Download Thesis.pdf

Thesis Supervisors:

Kenneth Charles Keiler, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

Author:

Ryan, Taryn Jeanne

Title:

Decoding the Mechanism of Action for Triazole and 8-hydroxyquinoline trans-Translation Inhibitors

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

trans-translation
antibiotic resistance
8-hydroxyquinoline
triazole
luciferase-based
click chemistry

File:

Download Taryn_Ryan_Honors_Thesis.pdf

Thesis Supervisors:

Kenneth Charles Keiler, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Dr. Sarah Ellen Ades, Faculty Reader

Author:

Davison, Alexis

Title:

Identification and Characterization of trans-Translation Inhibitors

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

trans-translation
antibiotic resistance
ribosome profiling
KKL-4669
high-throughput screen
luciferase reporter assay
bacterial pathogens
Caulobacter
in vitro transcription/translation assay

File:

Download Davison_Alexis_Thesis_Sp2020.pdf

Thesis Supervisors:

Ken Keiler, Thesis Supervisor
Ying Gu, Thesis Honors Advisor

Author:

Heilenman, Abigail

Title:

New Antibiotics Found in Trans-Translation Pathway

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

trans-translation
antibiotics
antibiotic resistance
L27
antibiotic targets
L27 ribosomal protein
trans-translation inhibitors
acylaminooxadiazole
tetrazole
triazole

File:

No files available due to restrictions.

Thesis Supervisors:

Ken Keiler, Thesis Supervisor
Ying Gu, Thesis Honors Advisor