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Author:

Yellin, Emma V

Title:

REACTIVE ASTROCYTES AND THEIR CONVERSION TO FUNCTIONAL NEURONS IN ISCHEMIC STROKE MOUSE MODEL

Area of Honors:

Biology

Keywords:

in vivo reprogramming
stroke
NeuroD1

File:

Download final_thesis_b.pdf

Thesis Supervisors:

Timothy J Jegla, Thesis Honors Advisor
Dr. Gong Chen, Thesis Supervisor

Author:

Jiang, Joanna

Title:

CTNNB1 Knockout in Inhibitory Neurons Contributes to Autism-Associated Behaviors in Mice

Area of Honors:

Biology

Keywords:

Autism
Behavior
Brain
Genetics
CTNNB1
Parvalbumin
Inhibitory
ASD

File:

Download Jiang_Thesis.pdf

Thesis Supervisors:

Dr. Yingwei Mao, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Chon, Grace Eunbin

Title:

THE GENETIC ANALYSIS OF DETONATOR IN D. MELANOGASTER DEVELOPMENT

Area of Honors:

Biology

Keywords:

detonator
drosophila melanogaster
UAS/Gal4
developmental biology
RNAi knockdown
deficiency
caudal regression
sirenomelia
genetic mutation
birth defect
TMEM132a
TMEM gene family

File:

Download FINAL.THESIS.pdf

Thesis Supervisors:

Aimin Liu, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Trabocco, Kyle Corsini

Title:

Genotypic Diversity of Coral in Palau

Area of Honors:

Biology

Keywords:

coral
bioerosion
ecology

File:

Download Kyle_Trabocco_Thesisupdate.pdf

Thesis Supervisors:

Iliana Brigitta Baums, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Huang, Pengqian

Title:

DIRECT ASTROCYTE TO NEURON REPROGRAMMING FOR FUNCTIONAL REPAIR IN INTRACRANIAL HEMORRHAGE MOUSE MODEL

Area of Honors:

Biology

Keywords:

ICH
collagenase
stroke
neuronal loss
direct conversion
NeuroD1
Hippocampus
Striatum
astrocytes
neuronal recovery

File:

Download Final_thesis.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Keefe, Matthew George

Title:

Direct Astrocyte-To-Neuron Conversion in Spinal Neurodegenerative Disease Models

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

NeuroD1
neurodegenerative disease
spinal cord injury
ALS
neuroscience
transdifferentiation

File:

Download Matthew_Keefe_Honors_Thesis.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor

Author:

Mok, Yung Kin

Title:

Beneficial Effects of NeuroD1-Mediated Direct Astrocyte-To-Neuron Conversion

Area of Honors:

Biology

Keywords:

glial scar
NeuroD1
stab injury
in vivo conversion
glia to neuron ratio
brain repair
CNS injury
astrocyte to neuron ratio
direct reprogramming
neuron regeneration

File:

Download Thesis__Yung_Kin_MOK.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor

Author:

Parry, Matthew

Title:

THE ROLE OF CLC-3 CHLORIDE CHANNELS IN THE PROGRESSION OF THE 5XFAD ALZHEIMER’S DISEASE MOUSE MODEL

Area of Honors:

Biomedical Engineering

Keywords:

CLC-3
Chloride Channels
Alzheimer's disease
Amyloid Beta
Aβ42
β-secretase
Beta Secretase
BACE1

File:

Download thesis_formatted_Honors.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Kevin Douglas Alloway, Thesis Honors Advisor

Author:

Redilla, Austin Scott

Title:

Investigation Of Direct Astrocyte-To-Neuron Conversion In Vivo In Spinal Cord Injury And ALS Mouse Models

Area of Honors:

Biology

Keywords:

NeuroD1
Spinal Cord Injury
Amyotrophic Lateral Sclerosis
SCI
ALS
ND1
NGN2
ISL1
LHX3
astrocyte-to-neuron conversion

File:

Download Redilla_Thesis_Final.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Hossain, Aasma

Title:

THE EFFECTS OF SELECTED TRANSCRIPTION FACTORS AND SMALL MOLECULES ON CONVERTING GLIOBLASTOMA CELLS TO GABAERGIC NEURONS

Area of Honors:

Biology

Keywords:

GABAergic neurons
Transcription factors
Glioblastoma
Cancer
Reprogramming efficiency

File:

Download Hossain_Aasma_Honors_Thesis_PDF_Final.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Michael Axtell, Thesis Honors Advisor