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Author:

Lee, Grace

Title:

The role of small molecules in reprogramming human astroglial cells into neurons

Area of Honors:

Biology

Keywords:

chemical reprogramming
small molecules
neurons
astrocytes
NeuroD1
conversion
NGN2

File:

Download Lee_Honors_Thesis_edited.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Kevin Douglas Alloway, Thesis Honors Advisor

Author:

Cai, Alice Y

Title:

REPROGRAMMING ASTROCYTES INTO FUNCTIONAL NEURONS FOR SPINAL CORD REPAIR

Area of Honors:

Biology

Keywords:

Spinal cord injury
Amyotrophic Lateral Sclerosis
Cell reprogramming
Spinal cord repair
Conversion
NeuroD1
Ngn2
Neurons

File:

Download Cai_Thesis_edited.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Timothy J Jegla, Thesis Honors Advisor

Author:

Yellin, Emma V

Title:

REACTIVE ASTROCYTES AND THEIR CONVERSION TO FUNCTIONAL NEURONS IN ISCHEMIC STROKE MOUSE MODEL

Area of Honors:

Biology

Keywords:

in vivo reprogramming
stroke
NeuroD1

File:

Download final_thesis_b.pdf

Thesis Supervisors:

Timothy J Jegla, Thesis Honors Advisor
Dr. Gong Chen, Thesis Supervisor

Author:

Huang, Pengqian

Title:

DIRECT ASTROCYTE TO NEURON REPROGRAMMING FOR FUNCTIONAL REPAIR IN INTRACRANIAL HEMORRHAGE MOUSE MODEL

Area of Honors:

Biology

Keywords:

ICH
collagenase
stroke
neuronal loss
direct conversion
NeuroD1
Hippocampus
Striatum
astrocytes
neuronal recovery

File:

Download Final_thesis.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Keefe, Matthew George

Title:

Direct Astrocyte-To-Neuron Conversion in Spinal Neurodegenerative Disease Models

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

NeuroD1
neurodegenerative disease
spinal cord injury
ALS
neuroscience
transdifferentiation

File:

Download Matthew_Keefe_Honors_Thesis.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor

Author:

Mok, Yung Kin

Title:

Beneficial Effects of NeuroD1-Mediated Direct Astrocyte-To-Neuron Conversion

Area of Honors:

Biology

Keywords:

glial scar
NeuroD1
stab injury
in vivo conversion
glia to neuron ratio
brain repair
CNS injury
astrocyte to neuron ratio
direct reprogramming
neuron regeneration

File:

Download Thesis__Yung_Kin_MOK.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor

Author:

Redilla, Austin Scott

Title:

Investigation Of Direct Astrocyte-To-Neuron Conversion In Vivo In Spinal Cord Injury And ALS Mouse Models

Area of Honors:

Biology

Keywords:

NeuroD1
Spinal Cord Injury
Amyotrophic Lateral Sclerosis
SCI
ALS
ND1
NGN2
ISL1
LHX3
astrocyte-to-neuron conversion

File:

Download Redilla_Thesis_Final.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Jayachandran, Kailash

Title:

INVESTIGATING THE MECHANISM OF NEUROD1 IN ASTROCYTE REPROGRAMMING BY CHROMATIN IMMUNOPRECIPITATION

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

Neuroscience
NeuroD1
Astrocytes
Glutamatergic Neurons
Reprogramming
Maria Krasilnikova
Kailash Jayachandran

File:

Download Jayachandran_Kailash_NeuroD1.pdf

Thesis Supervisors:

Maria Krasilnikova, Thesis Supervisor
Dr. Santhosh Girirajan, Thesis Honors Advisor