201. The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism Restricted (Penn State Only) Author: Dennis, Kady Title: The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism Area of Honors: Biochemistry and Molecular Biology Keywords: CX-5461mechanism of actionRNA Polymerase I inhibitorTopoisomerase II poison File: Login to Download Thesis Supervisors: Justin R Pritchard, Thesis SupervisorJoseph C. Reese, Thesis Honors Advisor
202. Understanding the Mechanisms Controlling the Localization of Microtubule Organization Proteins in Drosophila Neurons Restricted (Penn State Only) Author: Long, Melissa Title: Understanding the Mechanisms Controlling the Localization of Microtubule Organization Proteins in Drosophila Neurons Area of Honors: Biochemistry and Molecular Biology Keywords: DrosophilaNeuroscienceMicrotubule NucleationClathrin-Mediated EndocytosisWnt SignalingDendrite File: Login to Download Thesis Supervisors: Melissa Rolls, Thesis SupervisorDavid Scott Gilmour, Thesis Honors Advisor
203. Development of a Functional RNA-Identifying Computational Pipeline and its Application to SARS-CoV-2 Restricted (Penn State Only) Author: Forstmeier, Peter Title: Development of a Functional RNA-Identifying Computational Pipeline and its Application to SARS-CoV-2 Area of Honors: Biochemistry and Molecular Biology Keywords: SARS-CoV-2RNApseudoknotsSNPsRNA structure conservationframeshifting elementFSE File: Login to Download Thesis Supervisors: Philip C Bevilacqua, Thesis SupervisorTeh-Hui Kao, Thesis Honors Advisor
204. Mechanistic Study of Halogenation by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases Restricted (Penn State Only) Author: Katch, Bryce Title: Mechanistic Study of Halogenation by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases Area of Honors: Biochemistry and Molecular Biology Keywords: EnzymologyStructural BiologyC-H ActivationSadABesD File: Login to Download Thesis Supervisors: Amie Kathleen Boal, Thesis SupervisorTimothy Charles Meredith, Thesis Honors Advisor
205. High Resolution Structure and Neutralization Mechanism of 1G1 Fab Bound to Poliovirus Type 3 Restricted (Penn State Only) Author: Faust, Julia Title: High Resolution Structure and Neutralization Mechanism of 1G1 Fab Bound to Poliovirus Type 3 Area of Honors: Biochemistry and Molecular Biology Keywords: CryoEMpoliovirusSPV3virologyneutralizing antibody1G1 Fabstructural biology File: Login to Download Thesis Supervisors: Susan Hafenstein, Thesis SupervisorTimothy Charles Meredith, Thesis Honors Advisor
206. Cost-effective Molecular Weight Standards for Protein Size-exclusion Chromatography: HISftnA and HISDps Expression and Purification Restricted (Penn State Only) Author: Howells, Joshua Title: Cost-effective Molecular Weight Standards for Protein Size-exclusion Chromatography: HISftnA and HISDps Expression and Purification Area of Honors: Biochemistry and Molecular Biology Keywords: Size-exclusion chromatographymolecular weight standardsEscherichia coli bacterial ferritinEscherichia coli DNA-binding protein from starved cells File: Login to Download Thesis Supervisors: Song Tan, Thesis SupervisorSong Tan, Thesis Honors AdvisorJean-Paul Armache, Faculty Reader
207. Engineering Mitochondrial Transport Control Using Miro1 Restricted (Penn State Only) Author: Litvak, Michelle Title: Engineering Mitochondrial Transport Control Using Miro1 Area of Honors: Biochemistry and Molecular Biology Keywords: miro1proteinmitochondrial File: Login to Download Thesis Supervisors: Nikolay Dokholyan, Thesis SupervisorSanthosh Girirajan, Thesis Honors AdvisorJean-Paul Armache, Faculty Reader
208. Investigating Regeneration, Function, and Shape of Drosophila Sensory Dendrites Restricted (Penn State Only) Author: Bernard, Annabelle Title: Investigating Regeneration, Function, and Shape of Drosophila Sensory Dendrites Area of Honors: Biochemistry and Molecular Biology Keywords: Dendrite regenerationDrosophila melanogasterNociceptionFunctional recoveryPruning File: Login to Download Thesis Supervisors: Melissa Rolls, Thesis SupervisorTimothy Charles Meredith, Thesis Honors Advisor
209. Optimization of Size Exclusion Chromatography Protein Standards Restricted (Penn State Only) Author: Mongia, Advay Title: Optimization of Size Exclusion Chromatography Protein Standards Area of Honors: Biochemistry and Molecular Biology Keywords: Size Exclusion ChromatographyProtein Standardsprotein expressionprotein purificationgel filtration chromatographybacterioferritin File: Login to Download Thesis Supervisors: Song Tan, Thesis SupervisorJoseph C. Reese, Thesis Honors Advisor
210. New Antibiotics Found in Trans-Translation Pathway Restricted Author: Heilenman, Abigail Title: New Antibiotics Found in Trans-Translation Pathway Area of Honors: Biochemistry and Molecular Biology Keywords: trans-translationantibioticsantibiotic resistanceL27antibiotic targetsL27 ribosomal proteintrans-translation inhibitorsacylaminooxadiazoletetrazoletriazole File: No files available due to restrictions. Thesis Supervisors: Ken Keiler, Thesis SupervisorYing Gu, Thesis Honors Advisor