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Start Over Area of Honors Biochemistry and Molecular Biology Year 2019

1. Defining Stage-Specific and Constitutive Promoters in Plasmodium yoelii

open_access
Open Access
Author:
Finger, Logan
Title:
Defining Stage-Specific and Constitutive Promoters in Plasmodium yoelii
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Biochemistry and Molecular Biology
Malaria
Plasmodium
CRISPR/Cas9
Stage-Specific Promoters
Genetically Attenuated Parasites
File:
Download Finger_LE_Honors_Thesis_v3.pdf
Thesis Supervisors:
Scott Eugene Lindner, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

2. Diagnostic Evasion in Plasmodium falciparum Towards Hrp2-Sensitive Rapid Diagnostic Tests via pfhrp2 Gene Deletions

open_access
Open Access
Author:
Hollenbeak, Asher
Title:
Diagnostic Evasion in Plasmodium falciparum Towards Hrp2-Sensitive Rapid Diagnostic Tests via pfhrp2 Gene Deletions
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
malaria
rapid diagnostic tests
diagnostic
Plasmodium
falciparum
Linkage
Disequilibrium
File:
Download Hollenbeak_Thesis.pdf
Thesis Supervisors:
Maciej F Boni, Thesis Supervisor
Dr. Lorraine C Santy, Thesis Honors Advisor

3. CHARACTERIZATION OF GENETIC MUTATIONS IN EPIDEMIC STRAINS OF ZIKA VIRUS

open_access
Open Access
Author:
Horan, Sean
Title:
CHARACTERIZATION OF GENETIC MUTATIONS IN EPIDEMIC STRAINS OF ZIKA VIRUS
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Zika virus
mutation
NS5 polymerase
precursor membrane protein
envelope protein
pre-epidemic strain
epidemic strain
infection
virulence
convergent evolution
File:
Download Horan_FinalThesis.pdf
Thesis Supervisors:
Joyce Jose, Thesis Supervisor
Dr. Santhosh Girirajan, Thesis Honors Advisor

4. Structural Analysis of the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex

open_access
Open Access
Author:
Sowers, Rosalie
Title:
Structural Analysis of the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
chromatin
nucleosome
x-ray crystallography
MLL
MWRA
histone methyltransferase
File:
Download Sowers_thesis_final.pdf
Thesis Supervisors:
Song Tan, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Dr. Wendy Hanna-Rose, Faculty Reader

5. Examining Ribosomal Localization based on Microtubule Polarity in Drosophila melanogaster Neurons

open_access
Open Access
Author:
Lee, David Francis
Title:
Examining Ribosomal Localization based on Microtubule Polarity in Drosophila melanogaster Neurons
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Neurons
Drosophila
Ribosomes
Microtubules
Rolls
Lee
Fluorescent Microscopy
Developmental Biology
Biochemistry
Molecular Biology
Neuroscience
Trafficking
File:
Download FINAL.Thesis.Lee.David.pdf
Thesis Supervisors:
Melissa Rolls, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

6. The Effect of Subunit Deletions on SAGA Complex Binding in Sacharomyces Cerevisiae

open_access
Open Access
Author:
Driban, Matthew
Title:
The Effect of Subunit Deletions on SAGA Complex Binding in Sacharomyces Cerevisiae
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Yeast
Genomics
SAGA
Transcription
ChIP
Preinitiation Complex
TBP
Pol II
Knockouts
Heat Shock
Cell Stress
File:
Download MDriban_Thesis.pdf
Thesis Supervisors:
Benjamin Franklin Pugh, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor

7. MANIPULATION OF NAD+ IN C. ELEGANS AFFECTS HATCHING, LIFESPAN, AND SENSORY OUTPUT

open_access
Open Access
Author:
La Ganke, Nicole
Title:
MANIPULATION OF NAD+ IN C. ELEGANS AFFECTS HATCHING, LIFESPAN, AND SENSORY OUTPUT
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Nicotinamide adenine dinucleotide
C. elegans
sirtuins
oxidative stress
lifespan
delayed hatching
sensory response
File:
Download LaGanke_Final_Thesis.pdf
Thesis Supervisors:
Dr. Wendy Hanna-Rose, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor

11. Effects of Breaking Spectrin Network via Tobacco Etch Virus Protease on Heart and Fight Muscle in Drosophila

open_access
Open Access
Author:
Kiran, Amogh
Title:
Effects of Breaking Spectrin Network via Tobacco Etch Virus Protease on Heart and Fight Muscle in Drosophila
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
spectrin
cytoskeleton
drosophila heart
TEV protease
spectrin cleavage
File:
Download final_thesis_submission.pdf
Thesis Supervisors:
Claire Madison Thomas, Thesis Supervisor
Dr. Wendy Hanna-Rose, Thesis Honors Advisor

12. CHARACTERIZATION OF THE FaRLiP PHYCOBILIPROTEIN COMPLEX BY DELETION MUTAGENESIS IN THE CYANOBACTERIUM SYNECHOCOCCUS SP. PCC 7335

open_access
Open Access
Author:
Turner, Gavin M
Title:
CHARACTERIZATION OF THE FaRLiP PHYCOBILIPROTEIN COMPLEX BY DELETION MUTAGENESIS IN THE CYANOBACTERIUM SYNECHOCOCCUS SP. PCC 7335
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
FaRLiP
Cyanobacteria
Phycobilisome
Synechococcus sp. PCC 7335
File:
Download Turner_Gavin_FaRLiP_7335.pdf
Thesis Supervisors:
Donald Ashley Bryant, Thesis Supervisor
Dr. Ronald Albert Markle, Thesis Honors Advisor

14. CHARACTERIZATION OF A LIBRARY OF DEGENERATE OPERATOR SITES FOR THE TRANSCRIPTION FACTOR BETI FOR USE IN A MODEL-GUIDED DYNAMIC TIME-DELAY GENETIC CIRCUIT

open_access
Open Access
Author:
Clauer, Phillip
Title:
CHARACTERIZATION OF A LIBRARY OF DEGENERATE OPERATOR SITES FOR THE TRANSCRIPTION FACTOR BETI FOR USE IN A MODEL-GUIDED DYNAMIC TIME-DELAY GENETIC CIRCUIT
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Synthetic Biology
Metabolic Engineering
Biological Engineering
File:
Download Thesis_Clauer.pdf
Thesis Supervisors:
Dr. Howard M Salis, Thesis Supervisor
Dr. Wendy Hanna-Rose, Thesis Honors Advisor

15. POTENTIAL ROLE OF A TYROSINE LIGAND IN STABILIZING THE MIXED-VALENT DIIRON (II/III) COFACTOR OF MYO-INOSITOL OXYGENASE

open_access
Open Access
Author:
Cioffi, Katherine Joyann
Title:
POTENTIAL ROLE OF A TYROSINE LIGAND IN STABILIZING THE MIXED-VALENT DIIRON (II/III) COFACTOR OF MYO-INOSITOL OXYGENASE
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
myo-inositol oxygenase
metalloenzymes
mixed-valent diiron oxygenase
enzymology
File:
Download Cioffi_Final.pdf
Thesis Supervisors:
Joseph M Bollinger Jr., Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor

16. INVESTIGATING THE MECHANISM OF NEUROD1 IN ASTROCYTE REPROGRAMMING BY CHROMATIN IMMUNOPRECIPITATION

open_access
Open Access
Author:
Jayachandran, Kailash
Title:
INVESTIGATING THE MECHANISM OF NEUROD1 IN ASTROCYTE REPROGRAMMING BY CHROMATIN IMMUNOPRECIPITATION
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Neuroscience
NeuroD1
Astrocytes
Glutamatergic Neurons
Reprogramming
Maria Krasilnikova
Kailash Jayachandran
File:
Download Jayachandran_Kailash_NeuroD1.pdf
Thesis Supervisors:
Maria Krasilnikova, Thesis Supervisor
Dr. Santhosh Girirajan, Thesis Honors Advisor

17. Examining Drosophila melanogaster wing size upon tissue specific RNAi-induced knockdown of candidate gene regions of neurodevelopmental disorders

open_access
Open Access
Author:
Sarker, Avik Moni
Title:
Examining Drosophila melanogaster wing size upon tissue specific RNAi-induced knockdown of candidate gene regions of neurodevelopmental disorders
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Drosophila
neurodevelopmental disorder
CNV
RNAi
UAS/Gal4
deficiency
microdeletion
File:
Download ASarker_Thesis_SHC_Final_Submission.pdf
Thesis Supervisors:
Dr. Santhosh Girirajan, Thesis Supervisor
Dr. Santhosh Girirajan, Thesis Honors Advisor
David Scott Gilmour, Faculty Reader

18. Development of High Strength, Rapidly Degradable Bone Composites for Treatment of Osteoporosis

open_access
Open Access
Author:
Smith, Jessica
Title:
Development of High Strength, Rapidly Degradable Bone Composites for Treatment of Osteoporosis
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
biomaterials
citrate
osteoporosis
orthopedics
orthopedic materials
orthopedic fractures
POC
biomedical engineering
material science
bioengineering
xylitol
File:
Download BME_Thesis.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Ying Gu, Thesis Honors Advisor