1. DEVELOPMENT OF A CRISPR-CAS9 CONSTRUCT AIMED AT KNOCKING OUT SETD2 IN U2OS CELLS Open Access Author: Schultheis, Nicholas Charles Title: DEVELOPMENT OF A CRISPR-CAS9 CONSTRUCT AIMED AT KNOCKING OUT SETD2 IN U2OS CELLS Area of Honors: Biochemistry and Molecular Biology Keywords: CRISPRCAS9SETD2U2OSH3K36me3 File: Download Schultheis_Nicholas_Development_of_a_CRISPR-Cas9_Construct_Aimed_At_Knocking_Out_SetD2_in_U2OS_Cells.pdf Thesis Supervisors: Yanming Wang, Thesis SupervisorDr. Lorraine C Santy, Thesis Honors Advisor
2. Evaluation of Mechanisms Underlying Therapeutic Susceptibility and Immunotherapeutic Potential in SETD2 Mutant Kidney Cancers Open Access Author: Uzzo, Robert Title: Evaluation of Mechanisms Underlying Therapeutic Susceptibility and Immunotherapeutic Potential in SETD2 Mutant Kidney Cancers Area of Honors: Science Keywords: CRISPRCAS9SETD2Synthetic LethalityH3K36me3 File: Download Uzzo_Honors_Thesis_Final_Submission.pdf Thesis Supervisors: David James Degraff, Thesis SupervisorRonald Albert Markle, Thesis Honors Advisor
3. Effects of a SETD2 mutation on DNA damage response in renal cell carcinoma Open Access Author: Peskin, Jessica Title: Effects of a SETD2 mutation on DNA damage response in renal cell carcinoma Area of Honors: Biology (Abington) Keywords: SETD2Renal cell carcinomaDNA damage and repair File: Download thesis_final_submit__1_.pdf Thesis Supervisors: Thomas Michael Mcguire, III, Thesis SupervisorDavid Ruth, Thesis Honors Advisor
