Search

Start Over Area of Honors Biochemistry and Molecular Biology

202. The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism

restricted_to_institution
Restricted (Penn State Only)
Author:
Dennis, Kady
Title:
The Chemotherapeutic Agent CX-5461 Affects Cell Viability Through a Topoisomerase II Poison-Like Mechanism
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
CX-5461
mechanism of action
RNA Polymerase I inhibitor
Topoisomerase II poison
File:
Login to Download
Thesis Supervisors:
Justin R Pritchard, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

203. Understanding the Mechanisms Controlling the Localization of Microtubule Organization Proteins in Drosophila Neurons

restricted_to_institution
Restricted (Penn State Only)
Author:
Long, Melissa
Title:
Understanding the Mechanisms Controlling the Localization of Microtubule Organization Proteins in Drosophila Neurons
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Drosophila
Neuroscience
Microtubule Nucleation
Clathrin-Mediated Endocytosis
Wnt Signaling
Dendrite
File:
Login to Download
Thesis Supervisors:
Melissa Rolls, Thesis Supervisor
David Scott Gilmour, Thesis Honors Advisor

204. Development of a Functional RNA-Identifying Computational Pipeline and its Application to SARS-CoV-2

restricted_to_institution
Restricted (Penn State Only)
Author:
Forstmeier, Peter
Title:
Development of a Functional RNA-Identifying Computational Pipeline and its Application to SARS-CoV-2
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
SARS-CoV-2
RNA
pseudoknots
SNPs
RNA structure conservation
frameshifting element
FSE
File:
Login to Download
Thesis Supervisors:
Philip C Bevilacqua, Thesis Supervisor
Teh-Hui Kao, Thesis Honors Advisor

207. High Resolution Structure and Neutralization Mechanism of 1G1 Fab Bound to Poliovirus Type 3

restricted_to_institution
Restricted (Penn State Only)
Author:
Faust, Julia
Title:
High Resolution Structure and Neutralization Mechanism of 1G1 Fab Bound to Poliovirus Type 3
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
CryoEM
poliovirus
SPV3
virology
neutralizing antibody
1G1 Fab
structural biology
File:
Login to Download
Thesis Supervisors:
Susan Hafenstein, Thesis Supervisor
Timothy Charles Meredith, Thesis Honors Advisor

208. Cost-effective Molecular Weight Standards for Protein Size-exclusion Chromatography: HISftnA and HISDps Expression and Purification

restricted_to_institution
Restricted (Penn State Only)
Author:
Howells, Joshua
Title:
Cost-effective Molecular Weight Standards for Protein Size-exclusion Chromatography: HISftnA and HISDps Expression and Purification
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Size-exclusion chromatography
molecular weight standards
Escherichia coli bacterial ferritin
Escherichia coli DNA-binding protein from starved cells
File:
Login to Download
Thesis Supervisors:
Song Tan, Thesis Supervisor
Song Tan, Thesis Honors Advisor
Jean-Paul Armache, Faculty Reader

214. Chemogenetically Induced Activation of Cortical Somatostatin Interneurons Results in Enhanced Pyramidal Neuron Activity in Rodent Models

restricted_to_institution
Restricted (Penn State Only)
Author:
Hutsell, Alexander
Title:
Chemogenetically Induced Activation of Cortical Somatostatin Interneurons Results in Enhanced Pyramidal Neuron Activity in Rodent Models
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Chronic Stress
Chemogenetic Manipulation
Prelimbic Cortex
medial prefrontal cortex
Somatostatin Interneurons
Pyramidal Cells
Inhibition and Excitation in the brain
File:
Login to Download
Thesis Supervisors:
Bernhard Luscher, Thesis Supervisor
Timothy Charles Meredith, Thesis Honors Advisor

218. Localization of PIP2 in HGF-stimulated epithelial cell migration and Integrin Recycling

open_access
Open Access
Author:
Buskirk, Austin
Title:
Localization of PIP2 in HGF-stimulated epithelial cell migration and Integrin Recycling
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
epithelial cell migration
integrin recycling
Phosphatidylinositol-4
5-biphosphate (PIP2)
Epithelial-Mesenchymal Transition
Endosomal System
File:
Download Corrected_Austin_Buskirk_thesis.pdf
Thesis Supervisors:
Lorraine C Santy, Thesis Supervisor
Teh-Hui Kao, Thesis Honors Advisor

219. 1. Characterization of Twisters Ribozymes at Splice Sites 2. Development of a Computational Pipeline to Discover Small Self-cleaving Ribozymes with Helical Imperfections

restricted_to_institution
Restricted (Penn State Only)
Author:
Chang, Benjamin
Title:
1. Characterization of Twisters Ribozymes at Splice Sites 2. Development of a Computational Pipeline to Discover Small Self-cleaving Ribozymes with Helical Imperfections
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
RNA
Ribozymes
Splicing
High-throughput Pipeline
File:
Login to Download
Thesis Supervisors:
Philip C Bevilacqua, Thesis Supervisor
Joseph C. Reese, Thesis Honors Advisor

222. Adenylosuccinate Lyase Plays a Role in Neuromuscular Coordination

open_access
Open Access
Author:
Peifer, Mia
Title:
Adenylosuccinate Lyase Plays a Role in Neuromuscular Coordination
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
C. elegans
Adenylosuccinate Lyase Deficiency
Purine Metabolism
Neuromuscular Coordination
File:
Download Peifer_Mia_Adenylosuccinate_Lyase_Plays_a_Role_in_Neuromuscular_Coordination.pdf
Thesis Supervisors:
Wendy Hanna-Rose, Thesis Supervisor
Timothy Charles Meredith, Thesis Honors Advisor

223. Cost-effective Molecular Weight Standards for Protein Size Exclusion Chromatography

restricted_to_institution
Restricted (Penn State Only)
Author:
Sokol, Joshua
Title:
Cost-effective Molecular Weight Standards for Protein Size Exclusion Chromatography
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Size exclusion chromatography
Gel filtration chromatography
Globular
Liquid chromatography
Protein
Recombinant DNA
SEC-MALS
Analytical Ultracentrifugation
Sedimentation equilibrium
Metal affinity chromatography
Ion-exchange chromatography
Molecular weight
File:
Login to Download
Thesis Supervisors:
Song Tan, Thesis Supervisor
Ying Gu, Thesis Honors Advisor

224. Characterizing rescue of an Alzheimer's disease model in Drosophila by downregulation of heparan sulfate biosynthetic enzymes and treatment by bosutinib

open_access
Open Access
Author:
Swanson, Lindsey
Title:
Characterizing rescue of an Alzheimer's disease model in Drosophila by downregulation of heparan sulfate biosynthetic enzymes and treatment by bosutinib
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Alzheimer's disease
Heparan sulfate
Lipid metabolism
Autophagy
Mitochondria
Presenilin
File:
Download Swanson_Lindsey_HonorsThesis.pdf
Thesis Supervisors:
Scott Brian Selleck, Thesis Supervisor
Sarah Mary Assmann, Thesis Honors Advisor

226. Investigating Strain Level Diversity Among Natural Co-Isolated Vibrio Fischeri

restricted_to_institution
Restricted (Penn State Only)
Author:
Harter, Rachel
Title:
Investigating Strain Level Diversity Among Natural Co-Isolated Vibrio Fischeri
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
transformation
bacteria
strain diversity
genomic
genetic
vibrio fischeri
symbiosis
mutualism
euprymna scolopes
microbiology
molecular biology
biochemistry
quorum sensing
File:
Login to Download
Thesis Supervisors:
Timothy Iwao Miyashiro, Thesis Supervisor
Wendy Hanna-Rose, Thesis Honors Advisor

227. Investigating the Effects of H1N1 Influenza Infection on Vitamin D Metabolism and Response Gene Expression

open_access
Open Access
Author:
Kozloski, Suzanne
Title:
Investigating the Effects of H1N1 Influenza Infection on Vitamin D Metabolism and Response Gene Expression
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
Vitamin D
influenza
immunology
vitamin d metabolism
immune response
File:
Download SuzanneKozloski_HonorsThesis.pdf
Thesis Supervisors:
Margherita Teresa-Anna Cantorna, Thesis Supervisor
Santhosh Girirajan, Thesis Honors Advisor