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Start Over Thesis Supervisor Dr. William O Hancock

41. A Study in the Design of an Accelerated Wear Tester that is Compatible with a Particle Image Velocimetry and High Speed Camera Setup

open_access
Open Access
Author:
Brown, Edward Alexander
Title:
A Study in the Design of an Accelerated Wear Tester that is Compatible with a Particle Image Velocimetry and High Speed Camera Setup
Area of Honors:
Bioengineering
Keywords:
Accelerated Wear Tester
Particle Image Velocimetry
AWT
PIV
Heart Valve
Artificial Heart Valve
Fluid Dynamics
File:
Download Edward_A_Brown_Honors_Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

42. Development of A Multi-layered Micro-patterned Electrospun Mesh for Hernia Repair

open_access
Open Access
Author:
Orr, Sara A
Title:
Development of A Multi-layered Micro-patterned Electrospun Mesh for Hernia Repair
Area of Honors:
Bioengineering
Keywords:
electrospin
electrospun
hernia
mesh
File:
Download 1-Orr_Sara_TheDevelopmentofAMultiLayeredMicroPatternedElectrospunMeshforHerniaRepair.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Yong Wang, Faculty Reader

43. Modeling the Bidirectional Transport of Intracellular Cargos by Oppositely-directed Motor Proteins

open_access
Open Access
Author:
Mentley, Brandon Scott
Title:
Modeling the Bidirectional Transport of Intracellular Cargos by Oppositely-directed Motor Proteins
Area of Honors:
Bioengineering
Keywords:
kinesin
dynein
motor protein
bidirectional transport
matlab
simulation
File:
Download Brandon_Mentley_-_Thesis_Final_Fall15.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
John Fricks, Faculty Reader

44. THE EFFECTS OF BIOCONJUGATION OF CALCIUM PHOSPHOSILICATE NANOPARTICLES ON THE DELIVERY TO BREAST CANCER CELLS

open_access
Open Access
Author:
Gonzalez, Virginia Laura
Title:
THE EFFECTS OF BIOCONJUGATION OF CALCIUM PHOSPHOSILICATE NANOPARTICLES ON THE DELIVERY TO BREAST CANCER CELLS
Area of Honors:
Bioengineering
Keywords:
Calcium Phosphosilicate
Nanoparticles
Breast Cancer
Transendothelial Migration
File:
Download Honors_Thesis_VLG.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

45. β-Catenin Signaling Leading to the Maintenance and Differentiation of MC3T3 Cells in Response to Electrospun Nanofibers

open_access
Open Access
Author:
Nagurney, Rebecca Ann
Title:
β-Catenin Signaling Leading to the Maintenance and Differentiation of MC3T3 Cells in Response to Electrospun Nanofibers
Area of Honors:
Bioengineering
Keywords:
Nanofibers
Electrospinning
PMMA
PolyHEMA
Polyvinyl Alcohol
Beta-Catenin
Osteogenesis
File:
Download Nagurney_FinalThesis_BIOE_2016.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

46. Factors Impacting the Efficacy of Cell-mediated Drug Delivery to the Brain via the Blood Brain Barrier

open_access
Open Access
Author:
Selvi, Erhan Yavuz
Title:
Factors Impacting the Efficacy of Cell-mediated Drug Delivery to the Brain via the Blood Brain Barrier
Area of Honors:
Bioengineering
Keywords:
cell-mediated drug delivery
blood brain barrier
VE-cadherin
VCAM-1
ICAM-1
VLA-4
LFA-1
transendothelial migration
File:
Download SCHREYER_THESIS_4.11.16_final.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

47. The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells

open_access
Open Access
Author:
Porter, Michael John
Title:
The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells
Area of Honors:
Biomedical Engineering
Keywords:
Nanoparticle
Nanoparticles
IL-13
Interleukin
Glioma
GBM
Glioblastoma multiforme
conjugated
computational
kinetics
File:
Download Final_Thesis_Porter.pdf
Thesis Supervisors:
Sheereen Majd, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Herbert Herling Lipowsky, Faculty Reader

48. THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Mcculloch, Mary Elizabeth
Title:
THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
FAK
SRC
Tissue Engineering
hMSCs
migration
Focal adhesions
File:
Download HonorsFINALThesisDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

49. Comparing Novel Techniques for Measuring the Bending Modulus of Lipid Bilayer Membranes in Erythrocytes

open_access
Open Access
Author:
Frazzette, Nicholas James
Title:
Comparing Novel Techniques for Measuring the Bending Modulus of Lipid Bilayer Membranes in Erythrocytes
Area of Honors:
Bioengineering
Keywords:
mechanobiology
bending modulus
mechanotransduction
lipid bilayers
membrane bending
erythrocytes
TCSPC
fluorescence
File:
Download Frazzette_SHC_Thesis_v4.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Herbert Herling Lipowsky, Faculty Reader

51. Characterizing Melanoma Adhesion Dynamics: Thrombin Mediated Interactions and Polymorphic Neutrophil Deformability

open_access
Open Access
Author:
Lee, Deborah Snyder
Title:
Characterizing Melanoma Adhesion Dynamics: Thrombin Mediated Interactions and Polymorphic Neutrophil Deformability
Area of Honors:
Bioengineering
Keywords:
melanoma
polymorphic neutrophils
cellular adhesions
flow assays
bioengineering
cancer
thrombin
fibrin
endothelium
File:
Download undergraduate_thesis_deborah_lee_FINAL.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Yong Wang, Faculty Reader

53. An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells

open_access
Open Access
Author:
Swatski, Matthew David
Title:
An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells
Area of Honors:
Biomedical Engineering
Keywords:
epigenetics
nanofibers
PMMA
biomaterials
regenerative medicine
stem cells
tissue engineering
biomedical engineering
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Jian Yang, Faculty Reader

55. Melanoma Extravasation Through the Endothelium Affects Focal Adhesion Disassembly

open_access
Open Access
Author:
Eswar, Vikram Jayraj
Title:
Melanoma Extravasation Through the Endothelium Affects Focal Adhesion Disassembly
Area of Honors:
Biomedical Engineering
Keywords:
melanoma
Src
focal adhesion
endothelium
traction force
vinculin
contractility
extravasation
File:
Download Eswar_Thesis.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Esther Winter Gomez, Faculty Reader

57. Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides

open_access
Open Access
Author:
Lingafelt, Colin Mark
Title:
Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides
Area of Honors:
Biomedical Engineering
Keywords:
kinesins
microtubules
fluorescent nucleotides
binding rates
synthesis
Eg5
nucleation
tubulin
critical concentration
File:
Download thesis_ColinLingafelt_04102017_final.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader
Herbert Herling Lipowsky, Faculty Reader

58. RELATIONSHIP OF PLATELET ADHESION WITH SURFACE TOPOGRAPHY IN THE PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE

open_access
Open Access
Author:
Mueser, Ashlyn S
Title:
RELATIONSHIP OF PLATELET ADHESION WITH SURFACE TOPOGRAPHY IN THE PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE
Area of Honors:
Biomedical Engineering
Keywords:
PVAD
Platelet Adhesion
Surface Topography
Pediatric Ventricular Assist Devices
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

59. VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL

open_access
Open Access
Author:
McKellar, Brian U
Title:
VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL
Area of Honors:
Biomedical Engineering
Keywords:
Tissue Engineering
Bone
Biomineralization
Osteogenic differentiation
Stem cell
File:
Download McKellar_EpiBone_Thesis_FinalSchreyer_links.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

60. The impact of genetic variants on kinesin motor proteins and the link to neurological disorders

open_access
Open Access
Author:
Erdman, Marcus Orion
Title:
The impact of genetic variants on kinesin motor proteins and the link to neurological disorders
Area of Honors:
Biomedical Engineering
Keywords:
kinesin
neurological disorder
mutation
genomics
File:
Download Thesis_final_Marcus_Erdman.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Dr. Justin Lee Brown, Faculty Reader