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Start Over Thesis Supervisor Dr. William O Hancock Thesis Supervisor Dr. Justin Lee Brown

1. The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs)

open_access
Open Access
Author:
Sheldrake, Anne E
Title:
The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs)
Area of Honors:
Bioengineering
Keywords:
MEFs
tissue engineering
cardiac
acrylamide
bisacrylamide
heart
fibrillin
scar tissue
File:
Download sheldrake_anne_effect_of_susbstrate_stiffness.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

3. Nanofiber Control of Focal Adhesion Dynamics and Cell Migration for Regenerative Medicine

open_access
Open Access
Author:
Riley, Thomas Roberts
Title:
Nanofiber Control of Focal Adhesion Dynamics and Cell Migration for Regenerative Medicine
Area of Honors:
Bioengineering
Keywords:
Matlab
Image Processing
Focal Adhesion
Cell Migration
Nanofiber
Tissue Engineering
Regenerative Medicine
FAITS
File:
Download RileyThesisFinalDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

4. Single-molecule microscopy step detection algorithms: kinesin motor proteins and the cellulose synthesis complex

open_access
Open Access
Author:
Deffenbaugh, Nathan C
Title:
Single-molecule microscopy step detection algorithms: kinesin motor proteins and the cellulose synthesis complex
Area of Honors:
Bioengineering
Keywords:
kinesin
motor proteins
step detection
single-molecule
cellulose synthesis complex
hidden Markov model
File:
Download DeffenbaughNathan_SHCThesis_May2015.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Faculty Reader
Dr. Justin Lee Brown, Faculty Reader
Dr. William O Hancock, Thesis Honors Advisor

5. β-Catenin Signaling Leading to the Maintenance and Differentiation of MC3T3 Cells in Response to Electrospun Nanofibers

open_access
Open Access
Author:
Nagurney, Rebecca Ann
Title:
β-Catenin Signaling Leading to the Maintenance and Differentiation of MC3T3 Cells in Response to Electrospun Nanofibers
Area of Honors:
Bioengineering
Keywords:
Nanofibers
Electrospinning
PMMA
PolyHEMA
Polyvinyl Alcohol
Beta-Catenin
Osteogenesis
File:
Download Nagurney_FinalThesis_BIOE_2016.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

6. Factors Impacting the Efficacy of Cell-mediated Drug Delivery to the Brain via the Blood Brain Barrier

open_access
Open Access
Author:
Selvi, Erhan Yavuz
Title:
Factors Impacting the Efficacy of Cell-mediated Drug Delivery to the Brain via the Blood Brain Barrier
Area of Honors:
Bioengineering
Keywords:
cell-mediated drug delivery
blood brain barrier
VE-cadherin
VCAM-1
ICAM-1
VLA-4
LFA-1
transendothelial migration
File:
Download SCHREYER_THESIS_4.11.16_final.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

7. THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Mcculloch, Mary Elizabeth
Title:
THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
FAK
SRC
Tissue Engineering
hMSCs
migration
Focal adhesions
File:
Download HonorsFINALThesisDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

9. An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells

open_access
Open Access
Author:
Swatski, Matthew David
Title:
An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells
Area of Honors:
Biomedical Engineering
Keywords:
epigenetics
nanofibers
PMMA
biomaterials
regenerative medicine
stem cells
tissue engineering
biomedical engineering
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Jian Yang, Faculty Reader

10. Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides

open_access
Open Access
Author:
Lingafelt, Colin Mark
Title:
Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides
Area of Honors:
Biomedical Engineering
Keywords:
kinesins
microtubules
fluorescent nucleotides
binding rates
synthesis
Eg5
nucleation
tubulin
critical concentration
File:
Download thesis_ColinLingafelt_04102017_final.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader
Herbert Herling Lipowsky, Faculty Reader

11. VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL

open_access
Open Access
Author:
McKellar, Brian U
Title:
VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL
Area of Honors:
Biomedical Engineering
Keywords:
Tissue Engineering
Bone
Biomineralization
Osteogenic differentiation
Stem cell
File:
Download McKellar_EpiBone_Thesis_FinalSchreyer_links.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

12. The impact of genetic variants on kinesin motor proteins and the link to neurological disorders

open_access
Open Access
Author:
Erdman, Marcus Orion
Title:
The impact of genetic variants on kinesin motor proteins and the link to neurological disorders
Area of Honors:
Biomedical Engineering
Keywords:
kinesin
neurological disorder
mutation
genomics
File:
Download Thesis_final_Marcus_Erdman.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Dr. Justin Lee Brown, Faculty Reader

13. CALCIUM DOPED CITRATE BOUND BIOMATERIALS FOR MULTIFUNCTIONAL ORTHOPEDIC TISSUE ENGINEERING APPLICATIONS

open_access
Open Access
Author:
Fadel, John Elias
Title:
CALCIUM DOPED CITRATE BOUND BIOMATERIALS FOR MULTIFUNCTIONAL ORTHOPEDIC TISSUE ENGINEERING APPLICATIONS
Area of Honors:
Biomedical Engineering
Keywords:
Bone
orthopedics
orthopedic engineering
tissue engineering
bone implant
polymer
polymer engineering
characterization
materials
File:
Download Final_Thesis_Draft_FADEL.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

14. THE EFFECTS OF CELL MORPHOLOGY ON NANOPARTICLE UPTAKE AND UPTAKE AT THE LEADING EDGE IN MC3T3 CELLS

open_access
Open Access
Author:
Li, Harvey S
Title:
THE EFFECTS OF CELL MORPHOLOGY ON NANOPARTICLE UPTAKE AND UPTAKE AT THE LEADING EDGE IN MC3T3 CELLS
Area of Honors:
Biomedical Engineering
Keywords:
Biomedical engineering
cell morphology
cell culture
microcontact printing
immunostaining
immunofluorescence
live-cell imaging
cell leading edge
cell
y-27632
File:
Download Honors_Thesis_FINAL_v2.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

15. THE ROLE OF MECHANICALLY GATED ION CHANNELS IN REGULATING THE RESPONSE OF MESENCHYMAL STEM CELLS TO NANOFIBER ARCHITECTURE

open_access
Open Access
Author:
Wandling, Grant Donald
Title:
THE ROLE OF MECHANICALLY GATED ION CHANNELS IN REGULATING THE RESPONSE OF MESENCHYMAL STEM CELLS TO NANOFIBER ARCHITECTURE
Area of Honors:
Biomedical Engineering
Keywords:
Nanofibers
TREK-1
hMSCs
osteoblasts
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

16. THE EFFECT OF MICROFIBER MORPHOLOHY AND CELL DENSITY ON THE LOCALIZATION OF YAP PROTEIN IN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Steltz, Austin E
Title:
THE EFFECT OF MICROFIBER MORPHOLOHY AND CELL DENSITY ON THE LOCALIZATION OF YAP PROTEIN IN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
mesenchymal stem cell
msc
YAP
Yes Associated Protein
Mechanotransduction
Transduce
biology
biomedical engineering
electrospinning
fibers
flat
File:
Download Austin_Steltz_thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Yong Wang, Faculty Reader

17. Brownian Dynamics Simulation of Kinesin

open_access
Open Access
Author:
Cook, Zeke
Title:
Brownian Dynamics Simulation of Kinesin
Area of Honors:
Biomedical Engineering
Keywords:
Kinesin
Protein
Motor
Mechanobiology
Mechanochemistry
Processive
Fluorescence
Gold Nanoparticle
Tracking
Total Internal Reflection
Microscopy
Interferometric Scattering
Brownian
Dynamics
Brownian Dynamics
Molecular Modeling
Molecular Dynamics
File:
Download Cook_Annan_BrownianDynamicsSimulationofKinesinMotorProteinDynamics.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader