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1. THE EFFECTS OF THE TUMOR MICROENVIRONMENT ON ENDOTHELIAL CELLULAR ADHESION MOLECULE EXPRESSION

open_access
Open Access
Author:
Goodrich, Christopher James
Title:
THE EFFECTS OF THE TUMOR MICROENVIRONMENT ON ENDOTHELIAL CELLULAR ADHESION MOLECULE EXPRESSION
Area of Honors:
Bioengineering
Keywords:
cancer
metastasis
adhesion
ICAM-1
File:
Download Thesis_Reviewed_Final_-_Christopher_Goodrich.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

2. Design of a Tri-Phasic Biomechanical Model Describing Healthy and Cancerous Tissue

open_access
Open Access
Author:
Barber, Kathryn Irene
Title:
Design of a Tri-Phasic Biomechanical Model Describing Healthy and Cancerous Tissue
Area of Honors:
Engineering Science
Keywords:
computational modeling
tri-phasic model
cancer
brain tissue
magnetic resonance elastography
non-invasive diagnostic procedures
File:
Download Kathryn_Barber_Final_Senior_Thesis_2.pdf
Thesis Supervisors:
Corina Stefania Drapaca, Thesis Supervisor
Corina Stefania Drapaca, Thesis Supervisor
Judith A Todd Copley, Thesis Honors Advisor
Patrick James Drew, Faculty Reader

5. The Effects of Leptin Treatment on STAT/AKT/ERK Signaling Pathways in CRL2091 Fibroblast and HT1080 Fibrosarcoma Cells

open_access
Open Access
Author:
Gharib, Niloufar
Title:
The Effects of Leptin Treatment on STAT/AKT/ERK Signaling Pathways in CRL2091 Fibroblast and HT1080 Fibrosarcoma Cells
Area of Honors:
Veterinary and Biomedical Sciences
Keywords:
Leptin
obesity
cancer
ObRb
STAT
Akt
ERK
STAT3
ERK1/2
AKT1/2/3
signaling
leptin receptor
fibroblast
fibrosarcoma
File:
Download 1-Gharib_Niloufar_EffectsofLeptinTreatment.pdf
Thesis Supervisors:
Sagarika Kanjilal, Thesis Supervisor
Dr. Lester C Griel Jr., Thesis Honors Advisor

6. Encapsulation of Docetaxel in Calcium Phosphosilicate Nanoparticles and the Effects of Bioconjugation

open_access
Open Access
Author:
Hughes, Kelly E
Title:
Encapsulation of Docetaxel in Calcium Phosphosilicate Nanoparticles and the Effects of Bioconjugation
Area of Honors:
Bioengineering
Keywords:
nanoparticles
breast cancer
cancer
calcium phosphate
File:
Download Hughes_Honors_Thesis.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
James Hansell Adair, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

7. The Role of Peroxisome Proliferator-Activated Receptor-b/d (PPARb/d) in Transforming Growth Factor b-Induced Epithelial-Mesenchymal Transition (EMT) of Human Lung Adenocarcinoma Cell Line

open_access
Open Access
Author:
Ali, Ayesha S
Title:
The Role of Peroxisome Proliferator-Activated Receptor-b/d (PPARb/d) in Transforming Growth Factor b-Induced Epithelial-Mesenchymal Transition (EMT) of Human Lung Adenocarcinoma Cell Line
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
cancer
human lung adenocarcinoma
lung
ppar-b/d
tgf-b
File:
Download Thesis_Draft_9.pdf
Thesis Supervisors:
Jeffrey Maurice Peters, Thesis Supervisor
Dr. Sarah Ellen Ades, Thesis Honors Advisor
Richard John Frisque, Faculty Reader

8. Pterostilbene inhibits the growth of human non-small cell lung cancer cells by inducing cell cycle arrest

open_access
Open Access
Author:
Vuong, Ashley C
Title:
Pterostilbene inhibits the growth of human non-small cell lung cancer cells by inducing cell cycle arrest
Area of Honors:
Food Science
Keywords:
pterostilbene
food science
cell cycle arrest
lung cancer
cancer
blueberries
resveratrol
File:
Download Ashley_Vuong_-_Honors_Thesis.pdf
Thesis Supervisors:
Joshua D Lambert, Thesis Supervisor
Dr. Pamela A. Hankey-Giblin, Thesis Honors Advisor
John Neil Coupland, Faculty Reader

10. Impact Of Osteoblast-derived Bone Remodeling Cytokines On metastatic Breast Cancer Cell Dormancy

open_access
Open Access
Author:
Rutan, Emily Claire
Title:
Impact Of Osteoblast-derived Bone Remodeling Cytokines On metastatic Breast Cancer Cell Dormancy
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
breast cancer
bone remodeling
cytokines
cancer
dormancy
metastasis
metastases
IL-6
IL-1beta
TNF-alpha
osteoblasts
File:
Download 1-ECR_Thesis_Submit2.pdf
Thesis Supervisors:
Andrea Marie Mastro, Thesis Supervisor
Dr. Teh-hui Kao, Thesis Honors Advisor
Richard John Frisque, Faculty Reader

12. Establishment Of Subculture Protocol For The Maintenance Of Bxpc3 Cell Health In Preparation For In Vitro Cytoxicology Screening Of Calcium Phosphosilicate Nanoparticles

open_access
Open Access
Author:
Kumpf, Danielle Nicole
Title:
Establishment Of Subculture Protocol For The Maintenance Of Bxpc3 Cell Health In Preparation For In Vitro Cytoxicology Screening Of Calcium Phosphosilicate Nanoparticles
Area of Honors:
Biology
Keywords:
pancreatic
cancer
calcium phosphosilicate nanoparticles
drug delivery
File:
Download Kumpf_Final_Thesis.pdf
Thesis Supervisors:
James Hansell Adair, Thesis Supervisor
Richard Cyr, Thesis Honors Advisor

13. Potential Implications on the Giraffe DNA Repair Pathway through the Modification of MDC1

open_access
Open Access
Author:
Wood, Brendan Rich
Title:
Potential Implications on the Giraffe DNA Repair Pathway through the Modification of MDC1
Area of Honors:
Biology
Keywords:
Giraffe
Okapi
MDC1
H2AX
DSB Repair
Double-Stranded Break
cancer
non-homologous end joining
homologous recombination
File:
Download Wood_Brendan_Honors_Thesis_Sp2015.pdf
Thesis Supervisors:
Douglas Cavener, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

14. The differential effects of all-trans retinoic acid on retinoic acid receptor (RAR) and peroxisome proliferator-activated receptor (PPARβ/δ)-dependent signaling in the human NGP neuroblastoma cancer cell line.

open_access
Open Access
Author:
Krevitz, Jacqueline Anne
Title:
The differential effects of all-trans retinoic acid on retinoic acid receptor (RAR) and peroxisome proliferator-activated receptor (PPARβ/δ)-dependent signaling in the human NGP neuroblastoma cancer cell line.
Area of Honors:
Biology
Keywords:
PPAR
neuroblastoma
ngp
retinoic acid
atra
rar
cancer
File:
Download Jacqueline_Krevitz_final_thesis.pdf
Thesis Supervisors:
Jeffrey Maurice Peters, Thesis Supervisor
Dr. Stephen Wade Schaeffer, Thesis Honors Advisor

15. Characterizing Melanoma Adhesion Dynamics: Thrombin Mediated Interactions and Polymorphic Neutrophil Deformability

open_access
Open Access
Author:
Lee, Deborah Snyder
Title:
Characterizing Melanoma Adhesion Dynamics: Thrombin Mediated Interactions and Polymorphic Neutrophil Deformability
Area of Honors:
Bioengineering
Keywords:
melanoma
polymorphic neutrophils
cellular adhesions
flow assays
bioengineering
cancer
thrombin
fibrin
endothelium
File:
Download undergraduate_thesis_deborah_lee_FINAL.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Yong Wang, Faculty Reader

16. SYNTHESIS AND EFFECTS OF A PHOTOACTIVATED SILVER NANOPARTICLE PLATFORM DELIVERING MIR-148B IN LUNG ADENOCARCINOMA

open_access
Open Access
Author:
Chan, Alexander
Title:
SYNTHESIS AND EFFECTS OF A PHOTOACTIVATED SILVER NANOPARTICLE PLATFORM DELIVERING MIR-148B IN LUNG ADENOCARCINOMA
Area of Honors:
Biomedical Engineering
Keywords:
cancer
lung cancer
silver
silver nanoparticles
nanoparticles
theranostics
siRNA
miRNA
photothermal
File:
Download Chan_final_thesis.pdf
Thesis Supervisors:
Daniel J Hayes, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Scott H Medina, Faculty Reader

18. UTILIZATION OF THE RAPAMYCIN ASSAY TO VISUALIZE CYTOHESIN ASSOCIATION WITH RAB-POSITIVE COMPARTMENTS IN EPITHELIAL CELLS

open_access
Open Access
Author:
Rosenau, Jessica Lu
Title:
UTILIZATION OF THE RAPAMYCIN ASSAY TO VISUALIZE CYTOHESIN ASSOCIATION WITH RAB-POSITIVE COMPARTMENTS IN EPITHELIAL CELLS
Area of Honors:
Interdisciplinary in Biology and Biochemistry and Molecular Biology
Keywords:
epithelial cells
cancer
cell movement
emt
File:
Download Final_Thesis.pdf
Thesis Supervisors:
Dr. Lorraine C Santy, Thesis Supervisor
Benoit A Dayrat, Thesis Honors Advisor
Claire Madison Thomas, Faculty Reader

19. Yes-associated protein 1 localization in response to substrate architecture

open_access
Open Access
Author:
Chan, Coreena
Title:
Yes-associated protein 1 localization in response to substrate architecture
Area of Honors:
Biomedical Engineering
Keywords:
YAP
YAP1
yes-associated protein
yes-associated protein 1
nanofibers
osteogenesis
osteogenic differentiation
RhoA
FAK
focal adhesions
tissue engineering
Hippo signaling pathway
cancer
tumor suppression
File:
Download Chan_Coreena_Honors_Thesis_SP19.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Timothy J Jegla, Thesis Honors Advisor

20. A Quantitative Analysis of Subjective Measures of Well-being Among Uninsured and Insured Cancer Patients and Cancer Survivors

open_access
Open Access
Author:
Granahan, Brendan
Title:
A Quantitative Analysis of Subjective Measures of Well-being Among Uninsured and Insured Cancer Patients and Cancer Survivors
Area of Honors:
Health Policy and Administration
Keywords:
insurance
cancer
affordable care act
well-being
File:
Download Granahan__Brendan_Thesis.pdf
Thesis Supervisors:
Mark Sciegaj, Thesis Supervisor
Selena E Ortiz, Thesis Honors Advisor

21. Clinically Irrelevant Concentrations of Kinase Inhibitors Contribute to Failure of Drug Repurposing Efforts in Clinical Trials: a Meta-Analysis

open_access
Open Access
Author:
Shah, Anushka
Title:
Clinically Irrelevant Concentrations of Kinase Inhibitors Contribute to Failure of Drug Repurposing Efforts in Clinical Trials: a Meta-Analysis
Area of Honors:
Biology
Keywords:
clinical trials
repurposing
cancer
kinase inhibitors
meta-analysis
biology
in vitro
drug concentrations
File:
Download Shah_SHCThesis.pdf
Thesis Supervisors:
Justin R Pritchard, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor

22. The Role of IREa and p53 in UVB Sensitivity of Human Keratinocytes

open_access
Open Access
Author:
Ibinson, Jack
Title:
The Role of IREa and p53 in UVB Sensitivity of Human Keratinocytes
Area of Honors:
Immunology and Infectious Disease
Keywords:
IRE1
ER stress
p53
skin cancer
cancer
UV
Unfolded Protein Response
UPR
DNA Damage Response
DDR
UVB
UV-induced DDR
keratinocytes
HaCaT
N-TERT
File:
Download Ibinson_Jack_thesis.pdf
Thesis Supervisors:
Adam Bleier Glick, Thesis Supervisor
Pamela Hankey Giblin, Thesis Honors Advisor

23. Synthesis of Phosphatidylinositol 4,5-bisphosphate (PIP2) in Endosomal Compartments during Serum-Stimulated Cell Signaling

open_access
Open Access
Author:
Lee, Ellen
Title:
Synthesis of Phosphatidylinositol 4,5-bisphosphate (PIP2) in Endosomal Compartments during Serum-Stimulated Cell Signaling
Area of Honors:
Biochemistry and Molecular Biology
Keywords:
integrin recycling
epithelial cell migration
cancer
endosomes
File:
Download Lee_Ellen_Thesis2.pdf
Thesis Supervisors:
Lorraine C Santy, Thesis Supervisor
Song Tan, Thesis Honors Advisor

24. Health Disparities with Mammogram and Pap Test Utilization Among Low Income African American Women

open_access
Open Access
Author:
Kallur, Aarathi
Title:
Health Disparities with Mammogram and Pap Test Utilization Among Low Income African American Women
Area of Honors:
Health Policy and Administration
Keywords:
health disparities
mammograms
pap smear
cancer
preventative care
utilization rates
low income
black women
African American women
File:
Download Kallur_Final_Thesis_.pdf
Thesis Supervisors:
Jeannette A Rogowski, Thesis Supervisor
Selena E Ortiz, Thesis Honors Advisor