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Author:

Han, Anna Q.

Title:

THE ROLE OF CYTOSKELETON PROTEINS IN THE DETERMINATION OF NEURONAL POLARITY

Area of Honors:

Bioengineering

Keywords:

cytoskeleton proteins
cofilin
slingshot
LIM kinase
neuronal polarity
hippocampal neurons

File:

Download Han.Anna.Spring_2010_Thesis.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Gong Chen, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

Author:

Perry, Georgia L

Title:

EPIDEMIOLOGY OF GASTROINTESTINAL PARASITE INFECTIONS IN A WILD HERBIVORE

Area of Honors:

Biology

Keywords:

Trichostrongylus retortaeformis
gastrointestinal parasite

File:

Download G_Perry_Thesis.pdf

Thesis Supervisors:

Isabella Cattadori, Thesis Supervisor
Isabella Cattadori, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Qin, Mengying

Title:

REGULATION OF NEURONAL POLARITY BY CHANGING ACTIN AND MICROTUBULE DYNAMICS

Area of Honors:

Biology

Keywords:

Cofilin
Neuronal Polarity
Actin

File:

Download mwq5004_final_thesis.pdf

Thesis Supervisors:

Sarah Mary Assmann, Thesis Supervisor
Dr. Gong Chen, Thesis Supervisor
Sarah Mary Assmann, Thesis Honors Advisor

Author:

Parmar, Manpreet Kaur

Title:

The Function of Microtubule Polarity in Drosophila Dendrites

Area of Honors:

Biology

Keywords:

Microtubule Polarity
Dendrites
Drosophila melanogaster
Minus-end-out microtubule
Plus-end-out microtubule
polarized trafficking
Kap3RNAi
Rtnl2RNAi
Class I neuron
ddaE
morphology
endosomes
mitochondria

File:

Download Parmar_Manpreet_FunctionofMicrotubulePolarityinDrosophilaDendrites__Final_4-9-12_.pdf

Thesis Supervisors:

Melissa Rolls, Thesis Supervisor
Dr. Stephen Wade Schaeffer, Thesis Honors Advisor
Dr. Gong Chen, Faculty Reader

Author:

Zhang, Ce

Title:

The Role of Extrasynaptic GABAA Receptors in Regulation of Inhibitory Synapses

Area of Honors:

Biology

Keywords:

GABA
neuroscience
biology
brain inhibition

File:

Download Zhang_Ce_BiologyThesis.pdf

Thesis Supervisors:

Dr. Bernhard Lüscher, Thesis Honors Advisor
Dr. Gong Chen, Thesis Supervisor

Author:

Fassihi, Safa Cyrus

Title:

The Effects of Early Iron Deficiency on Brain Iron and Monoamine Levels in a Rat Model

Area of Honors:

Biology

Keywords:

Iron
Deficiency
Rats
Brain
Monoamine
Neurotransmitter

File:

Download Final_Thesis_Submission.pdf

Thesis Supervisors:

Dr. Erica Unger, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor
Dr. Gong Chen, Faculty Reader

Author:

Khristov, Vladimir Rouskov

Title:

Understanding the interactions between GABAAR and synaptic adhesion proteins neuroligin1 And neuroligin2

Area of Honors:

Biology

Keywords:

Neurolign
GABA
Immunoprufication
Western

File:

Download Khristov_Vladimir_GABAAR_Neuroligin.pdf

Thesis Supervisors:

Dr. Bernhard Lüscher, Thesis Supervisor
Dr. Gong Chen, Faculty Reader
Craig Eugene Cameron, Thesis Honors Advisor

Author:

Ackerman, Colin Thomas

Title:

Dominant Negative Suppression of Kv12 Channels in Transgenic Mice

Area of Honors:

Biology

Keywords:

Kv12
Potassium
Transgenic
Mice
Dominant Negative

File:

Download SHC_Thesis.pdf

Thesis Supervisors:

Timothy J Jegla, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Valerio, Emily Anne

Title:

The Identification and Characterization of Sufu Interacting Proteins

Area of Honors:

Biology

Keywords:

Hh signaling
Sufu
Gli
T131L
LOC67513
Gps1

File:

Download Thesis_FINAL3.pdf

Thesis Supervisors:

Aimin Liu, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Sikora, Michael Joseph

Title:

Modelling Male Demographic Histories from Y-chromosome Data by Measuring Star-shaped Genealogies

Area of Honors:

Biology

Keywords:

Y-chromosome
R1b
E1b1a
Neolithic
Expansion
Genealogy

File:

Download Sikora_Michael_ModellingMaleDemFINAL.pdf

Thesis Supervisors:

Webb Colby Miller, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Marshall, Jared Scott

Title:

Synthesis of Novel Bivalent Mimetic Ligands for Mannose-6-phosphate Receptors

Area of Honors:

Chemistry

Keywords:

M6P
GlcNAc-M6P
hydrolase sorting
mimetic ligands

File:

Download Marshall_Jared_synthofbivalent.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Przemyslaw Maslak, Thesis Honors Advisor
Philip C. Bevilacqua, Faculty Reader

Author:

Vedak, Shivam

Title:

The Salience Of Lower-order Features In Highly Self-similar Wallpaper Groups

Area of Honors:

Interdisciplinary in Biology and Psychology

Keywords:

symmetry
perception
vision
wallpaper group
isometry
regularity
pattern
geometry
group theory

File:

Download Vedak_Shivam_wallpapergroupslowerorderfeatures.pdf

Thesis Supervisors:

Dr. Rick Owen Gilmore, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor
Rick R Jacobs, Thesis Honors Advisor

Author:

Yeh, Hana

Title:

Using Small Molecules To Convert Human Astrocytes Into Functional Neurons

Area of Honors:

Biology

Keywords:

gong chen
astrocytes
small molecules
conversion

File:

Download Honors_Thesis_Hana.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Kim, Julie Sun

Title:

Exploring GABA Function in Rett Syndrome

Area of Honors:

Chemistry

Keywords:

Neuroscience
Rett Syndrome
Dendritic Spine Morphogenesis
GABA

File:

Download JKHonorsThesis_Final.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Przemyslaw Maslak, Thesis Honors Advisor

Author:

Adamiak, William Noel

Title:

Adult observers' sensitivity to optic flow varies by pattern and speed

Area of Honors:

Interdisciplinary in Biology and Psychology

Keywords:

optic flow
psychophysics
global motion
perception
behavioral neuroscience

File:

Download The_Adamiak_Thesis.pdf

Thesis Supervisors:

Dr. Rick Owen Gilmore, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor
Dr. Richard Alan Carlson, Faculty Reader

Author:

Wood, Brendan Rich

Title:

Potential Implications on the Giraffe DNA Repair Pathway through the Modification of MDC1

Area of Honors:

Biology

Keywords:

Giraffe
Okapi
MDC1
H2AX
DSB Repair
Double-Stranded Break
cancer
non-homologous end joining
homologous recombination

File:

Download Wood_Brendan_Honors_Thesis_Sp2015.pdf

Thesis Supervisors:

Douglas Cavener, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Lee, Grace

Title:

The role of small molecules in reprogramming human astroglial cells into neurons

Area of Honors:

Biology

Keywords:

chemical reprogramming
small molecules
neurons
astrocytes
NeuroD1
conversion
NGN2

File:

Download Lee_Honors_Thesis_edited.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Kevin Douglas Alloway, Thesis Honors Advisor

Author:

Lin, John Lizhong

Title:

The Effect of Selected Transcription Factors on Inhibiting In Vitro And In Vivo Hepatocellular Carcinoma Development

Area of Honors:

Biology

Keywords:

liver cancer
HCC
Hepatocellular Carcinoma
HepG2
Hep3B
AFP
Ki67
Gene Therapy
Viral Infection
Transfection
Cancer Treatment

File:

Download Lin_John_Liver_Cancer_Therapy.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Cai, Alice Y

Title:

REPROGRAMMING ASTROCYTES INTO FUNCTIONAL NEURONS FOR SPINAL CORD REPAIR

Area of Honors:

Biology

Keywords:

Spinal cord injury
Amyotrophic Lateral Sclerosis
Cell reprogramming
Spinal cord repair
Conversion
NeuroD1
Ngn2
Neurons

File:

Download Cai_Thesis_edited.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Timothy J Jegla, Thesis Honors Advisor

Author:

Henry, Jessica Behin

Title:

NOVEL 3-DIMENSIONAL ELECTRON MICROSCOPIC ANALYSIS OF MITOCHONDRIAL MORPHOLOGY IN AGED AND ISCHEMIC FEMALE RAT HEART

Area of Honors:

Biology

Keywords:

ischemic injury
mitochondria
aging
menopause
heart

File:

Download Henry_Jessica_Thesis.pdf

Thesis Supervisors:

Dr. Donna Hope Korzick, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Yellin, Emma V

Title:

REACTIVE ASTROCYTES AND THEIR CONVERSION TO FUNCTIONAL NEURONS IN ISCHEMIC STROKE MOUSE MODEL

Area of Honors:

Biology

Keywords:

in vivo reprogramming
stroke
NeuroD1

File:

Download final_thesis_b.pdf

Thesis Supervisors:

Timothy J Jegla, Thesis Honors Advisor
Dr. Gong Chen, Thesis Supervisor

Author:

Jiang, Joanna

Title:

CTNNB1 Knockout in Inhibitory Neurons Contributes to Autism-Associated Behaviors in Mice

Area of Honors:

Biology

Keywords:

Autism
Behavior
Brain
Genetics
CTNNB1
Parvalbumin
Inhibitory
ASD

File:

Download Jiang_Thesis.pdf

Thesis Supervisors:

Dr. Yingwei Mao, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Chon, Grace Eunbin

Title:

THE GENETIC ANALYSIS OF DETONATOR IN D. MELANOGASTER DEVELOPMENT

Area of Honors:

Biology

Keywords:

detonator
drosophila melanogaster
UAS/Gal4
developmental biology
RNAi knockdown
deficiency
caudal regression
sirenomelia
genetic mutation
birth defect
TMEM132a
TMEM gene family

File:

Download FINAL.THESIS.pdf

Thesis Supervisors:

Aimin Liu, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Trabocco, Kyle Corsini

Title:

Genotypic Diversity of Coral in Palau

Area of Honors:

Biology

Keywords:

coral
bioerosion
ecology

File:

Download Kyle_Trabocco_Thesisupdate.pdf

Thesis Supervisors:

Iliana Brigitta Baums, Thesis Supervisor
Dr. Gong Chen, Thesis Honors Advisor

Author:

Huang, Pengqian

Title:

DIRECT ASTROCYTE TO NEURON REPROGRAMMING FOR FUNCTIONAL REPAIR IN INTRACRANIAL HEMORRHAGE MOUSE MODEL

Area of Honors:

Biology

Keywords:

ICH
collagenase
stroke
neuronal loss
direct conversion
NeuroD1
Hippocampus
Striatum
astrocytes
neuronal recovery

File:

Download Final_thesis.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Keefe, Matthew George

Title:

Direct Astrocyte-To-Neuron Conversion in Spinal Neurodegenerative Disease Models

Area of Honors:

Biochemistry and Molecular Biology

Keywords:

NeuroD1
neurodegenerative disease
spinal cord injury
ALS
neuroscience
transdifferentiation

File:

Download Matthew_Keefe_Honors_Thesis.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Craig Eugene Cameron, Thesis Honors Advisor

Author:

Mok, Yung Kin

Title:

Beneficial Effects of NeuroD1-Mediated Direct Astrocyte-To-Neuron Conversion

Area of Honors:

Biology

Keywords:

glial scar
NeuroD1
stab injury
in vivo conversion
glia to neuron ratio
brain repair
CNS injury
astrocyte to neuron ratio
direct reprogramming
neuron regeneration

File:

Download Thesis__Yung_Kin_MOK.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Richard W Ordway, Thesis Honors Advisor

Author:

Parry, Matthew

Title:

THE ROLE OF CLC-3 CHLORIDE CHANNELS IN THE PROGRESSION OF THE 5XFAD ALZHEIMER’S DISEASE MOUSE MODEL

Area of Honors:

Biomedical Engineering

Keywords:

CLC-3
Chloride Channels
Alzheimer's disease
Amyloid Beta
Aβ42
β-secretase
Beta Secretase
BACE1

File:

Download thesis_formatted_Honors.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Kevin Douglas Alloway, Thesis Honors Advisor

Author:

Redilla, Austin Scott

Title:

Investigation Of Direct Astrocyte-To-Neuron Conversion In Vivo In Spinal Cord Injury And ALS Mouse Models

Area of Honors:

Biology

Keywords:

NeuroD1
Spinal Cord Injury
Amyotrophic Lateral Sclerosis
SCI
ALS
ND1
NGN2
ISL1
LHX3
astrocyte-to-neuron conversion

File:

Download Redilla_Thesis_Final.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Bernhard Lüscher, Thesis Honors Advisor

Author:

Hossain, Aasma

Title:

THE EFFECTS OF SELECTED TRANSCRIPTION FACTORS AND SMALL MOLECULES ON CONVERTING GLIOBLASTOMA CELLS TO GABAERGIC NEURONS

Area of Honors:

Biology

Keywords:

GABAergic neurons
Transcription factors
Glioblastoma
Cancer
Reprogramming efficiency

File:

Download Hossain_Aasma_Honors_Thesis_PDF_Final.pdf

Thesis Supervisors:

Dr. Gong Chen, Thesis Supervisor
Dr. Michael Axtell, Thesis Honors Advisor