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Start Over Area of Honors Biomedical Engineering

1. Targeted Sequencing Of Chromosome 9 Genes Associated With Papillary Type 1 Renal Cell Carcinoma

open_access
Open Access
Author:
Belsky, Michael Alan
Title:
Targeted Sequencing Of Chromosome 9 Genes Associated With Papillary Type 1 Renal Cell Carcinoma
Area of Honors:
Biomedical Engineering
Keywords:
Cancer
next generation sequencing
renal cell carcinoma
targeted sequencing
papillary type 1
File:
Download Belsky_Thesis_Final.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William A La Framboise, Faculty Reader

4. The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells

open_access
Open Access
Author:
Porter, Michael John
Title:
The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells
Area of Honors:
Biomedical Engineering
Keywords:
Nanoparticle
Nanoparticles
IL-13
Interleukin
Glioma
GBM
Glioblastoma multiforme
conjugated
computational
kinetics
File:
Download Final_Thesis_Porter.pdf
Thesis Supervisors:
Sheereen Majd, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Herbert Herling Lipowsky, Faculty Reader

5. THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Mcculloch, Mary Elizabeth
Title:
THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
FAK
SRC
Tissue Engineering
hMSCs
migration
Focal adhesions
File:
Download HonorsFINALThesisDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

8. Membrane Microdomains Regulate Focal Adhesion Size in Bovine Aortic Endothelial Cells

open_access
Open Access
Author:
Culver, Margaret Frances
Title:
Membrane Microdomains Regulate Focal Adhesion Size in Bovine Aortic Endothelial Cells
Area of Honors:
Biomedical Engineering
Keywords:
Focal Adhesion
Lipid Rafts
Non-lipid amphiphiles
File:
Download Final_Thesis_for_submission_pdf.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

9. An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells

open_access
Open Access
Author:
Swatski, Matthew David
Title:
An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells
Area of Honors:
Biomedical Engineering
Keywords:
epigenetics
nanofibers
PMMA
biomaterials
regenerative medicine
stem cells
tissue engineering
biomedical engineering
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Jian Yang, Faculty Reader

11. Melanoma Extravasation Through the Endothelium Affects Focal Adhesion Disassembly

open_access
Open Access
Author:
Eswar, Vikram Jayraj
Title:
Melanoma Extravasation Through the Endothelium Affects Focal Adhesion Disassembly
Area of Honors:
Biomedical Engineering
Keywords:
melanoma
Src
focal adhesion
endothelium
traction force
vinculin
contractility
extravasation
File:
Download Eswar_Thesis.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Esther Winter Gomez, Faculty Reader

13. Impact of Pulsatility and Flow Rates on Hemodynamic Energy Transmission in an Adult ECLS System

open_access
Open Access
Author:
Wolfe, Rachel Morgan
Title:
Impact of Pulsatility and Flow Rates on Hemodynamic Energy Transmission in an Adult ECLS System
Area of Honors:
Biomedical Engineering
Keywords:
Extracorporeal life support
Diagonal pump
XLung oxygenator
Adult
Pulsatile flow
Extracorporeal life support
Diagonal pump
XLung oxygenator
Adult
Pulsatile flow
File:
Download WolfeRachel_FinalThesisPDF.pdf
Thesis Supervisors:
Akif Undar, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor

14. Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides

open_access
Open Access
Author:
Lingafelt, Colin Mark
Title:
Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides
Area of Honors:
Biomedical Engineering
Keywords:
kinesins
microtubules
fluorescent nucleotides
binding rates
synthesis
Eg5
nucleation
tubulin
critical concentration
File:
Download thesis_ColinLingafelt_04102017_final.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader
Herbert Herling Lipowsky, Faculty Reader

15. RELATIONSHIP OF PLATELET ADHESION WITH SURFACE TOPOGRAPHY IN THE PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE

open_access
Open Access
Author:
Mueser, Ashlyn S
Title:
RELATIONSHIP OF PLATELET ADHESION WITH SURFACE TOPOGRAPHY IN THE PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE
Area of Honors:
Biomedical Engineering
Keywords:
PVAD
Platelet Adhesion
Surface Topography
Pediatric Ventricular Assist Devices
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

16. VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL

open_access
Open Access
Author:
McKellar, Brian U
Title:
VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL
Area of Honors:
Biomedical Engineering
Keywords:
Tissue Engineering
Bone
Biomineralization
Osteogenic differentiation
Stem cell
File:
Download McKellar_EpiBone_Thesis_FinalSchreyer_links.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

18. The impact of genetic variants on kinesin motor proteins and the link to neurological disorders

open_access
Open Access
Author:
Erdman, Marcus Orion
Title:
The impact of genetic variants on kinesin motor proteins and the link to neurological disorders
Area of Honors:
Biomedical Engineering
Keywords:
kinesin
neurological disorder
mutation
genomics
File:
Download Thesis_final_Marcus_Erdman.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Dr. Justin Lee Brown, Faculty Reader

19. A Study of the Effect of Hematocrit on Weaning in the 12 cc Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Gallagher, Maureen Brenna
Title:
A Study of the Effect of Hematocrit on Weaning in the 12 cc Penn State Pediatric Ventricular Assist Device
Area of Honors:
Biomedical Engineering
Keywords:
PVAD
artificial heart
hematocrit
weaning
fluid dynamics
File:
Download Gallagher_Schreyer_Thesis_FINAL.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader
Dr. William O Hancock, Faculty Reader

20. Design, construction, and testing of a pneumatic vibrotactile stimulus system for use with awake, behaving mice

open_access
Open Access
Author:
Cook, Alexander Philip
Title:
Design, construction, and testing of a pneumatic vibrotactile stimulus system for use with awake, behaving mice
Area of Honors:
Biomedical Engineering
Keywords:
Neurovascular coupling
Electrophysiology
Passive touch
Pneumatic system
Vibrotactile stimulus
File:
Download Cook_Alexander_PneumaticSystem.pdf
Thesis Supervisors:
Patrick James Drew, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Nanyin Zhang, Faculty Reader

21. Pulsatile Assessment Of The FDA Computational Study Of Fluid Flow In Biomedical Devices

open_access
Open Access
Author:
Kessler, Joshua C
Title:
Pulsatile Assessment Of The FDA Computational Study Of Fluid Flow In Biomedical Devices
Area of Honors:
Biomedical Engineering
Keywords:
FDA
Turbulence
Computational Fluid Dynamics
CFD
LDV
Benchmark Nozzle Model
Critical Path Initiative
Pulsatile Flow
File:
Download Thesisv_schreyer.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Pak Kin Wong, Faculty Reader

22. CHARACTERIZATION OF THROMBI THROUGH MRI AND HISTOLOGICAL ANALYSIS OF ERYTHROCYTE GHOST CLOTS

open_access
Open Access
Author:
Hagenah, Kristen E
Title:
CHARACTERIZATION OF THROMBI THROUGH MRI AND HISTOLOGICAL ANALYSIS OF ERYTHROCYTE GHOST CLOTS
Area of Honors:
Biomedical Engineering
Keywords:
Ghost Cells
Quantitative Susceptibility Mapping
Left Ventricular Thrombus
File:
Download Hagenah_Kristen_Schreyer_Thesis_Final_.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

23. CALCIUM DOPED CITRATE BOUND BIOMATERIALS FOR MULTIFUNCTIONAL ORTHOPEDIC TISSUE ENGINEERING APPLICATIONS

open_access
Open Access
Author:
Fadel, John Elias
Title:
CALCIUM DOPED CITRATE BOUND BIOMATERIALS FOR MULTIFUNCTIONAL ORTHOPEDIC TISSUE ENGINEERING APPLICATIONS
Area of Honors:
Biomedical Engineering
Keywords:
Bone
orthopedics
orthopedic engineering
tissue engineering
bone implant
polymer
polymer engineering
characterization
materials
File:
Download Final_Thesis_Draft_FADEL.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

24. A CONTROL STUDY USING DNA TO TEST THE EFFECTS OF SHEAR STRESS ON VON WILLEBRAND FACTOR

open_access
Open Access
Author:
Jankowska, Maya Ann-Marie
Title:
A CONTROL STUDY USING DNA TO TEST THE EFFECTS OF SHEAR STRESS ON VON WILLEBRAND FACTOR
Area of Honors:
Biomedical Engineering
Keywords:
von willebrand factor
vwf
optical trap
fluid shear
LVADS
plasmid
fluid mechanics
optical tweezers
shear stress
acquired von willebrand syndrome
File:
Download vWF_Thesis_wTemplate_Maya2.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

28. SYNTHESIS AND EFFECTS OF A PHOTOACTIVATED SILVER NANOPARTICLE PLATFORM DELIVERING MIR-148B IN LUNG ADENOCARCINOMA

open_access
Open Access
Author:
Chan, Alexander
Title:
SYNTHESIS AND EFFECTS OF A PHOTOACTIVATED SILVER NANOPARTICLE PLATFORM DELIVERING MIR-148B IN LUNG ADENOCARCINOMA
Area of Honors:
Biomedical Engineering
Keywords:
cancer
lung cancer
silver
silver nanoparticles
nanoparticles
theranostics
siRNA
miRNA
photothermal
File:
Download Chan_final_thesis.pdf
Thesis Supervisors:
Daniel J Hayes, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Scott H Medina, Faculty Reader

29. THE FUNCTIONAL CONNECTIVITY CHANGES IN THE RAT BRAIN FOLLOWING ACUTE AND CHRONIC NICOTINE ADMINISTRATION

open_access
Open Access
Author:
Roby, Alison C
Title:
THE FUNCTIONAL CONNECTIVITY CHANGES IN THE RAT BRAIN FOLLOWING ACUTE AND CHRONIC NICOTINE ADMINISTRATION
Area of Honors:
Biomedical Engineering
Keywords:
functional connectivity
nicotine
individual difference
acute response
File:
Download thesis_Roby_Alison_final_links.pdf
Thesis Supervisors:
Dr. Nanyin Zhang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

30. EXPERIMENTAL PLATFORM SIMULATING THE MECHANICAL EFFECTS OF DIAPHRAGMATIC MOTION ON INFERIOR VENA CAVA COLLAPSIBILITY

open_access
Open Access
Author:
Crompton, Philip Edward
Title:
EXPERIMENTAL PLATFORM SIMULATING THE MECHANICAL EFFECTS OF DIAPHRAGMATIC MOTION ON INFERIOR VENA CAVA COLLAPSIBILITY
Area of Honors:
Biomedical Engineering
Keywords:
IVC filter
IVC collapse
diaphragmatic motion
inferior vena cava
File:
Download Crompton_Thesis2.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Justin Lee Brown, Thesis Honors Advisor

31. Assessment of Demographic, Anthropometric, and Physical Performance Variables As Predictors of Sprint Cycling Power

open_access
Open Access
Author:
Mellen, James Scott
Title:
Assessment of Demographic, Anthropometric, and Physical Performance Variables As Predictors of Sprint Cycling Power
Area of Honors:
Biomedical Engineering
Keywords:
cycling
vertical jump
wearable measurement device
sprint
File:
Download James_Mellen_Thesis_Final_Draft__3-30-18_.pdf
Thesis Supervisors:
Giampietro Luciano Vairo, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

32. Investigating the Impact of Flow Recirculation on Cellular Uptake of Nanoparticles

open_access
Open Access
Author:
Boland, Samuel Fares
Title:
Investigating the Impact of Flow Recirculation on Cellular Uptake of Nanoparticles
Area of Honors:
Biomedical Engineering
Keywords:
nanoparticles
atherosclerosis
flow chamber
finite element analysis
drug delivery
fluid dynamics
cell mechanics
File:
Download Boland_Thesis_Final.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Dr. Justin Lee Brown, Thesis Honors Advisor

33. THE EFFECTS OF CELL MORPHOLOGY ON NANOPARTICLE UPTAKE AND UPTAKE AT THE LEADING EDGE IN MC3T3 CELLS

open_access
Open Access
Author:
Li, Harvey S
Title:
THE EFFECTS OF CELL MORPHOLOGY ON NANOPARTICLE UPTAKE AND UPTAKE AT THE LEADING EDGE IN MC3T3 CELLS
Area of Honors:
Biomedical Engineering
Keywords:
Biomedical engineering
cell morphology
cell culture
microcontact printing
immunostaining
immunofluorescence
live-cell imaging
cell leading edge
cell
y-27632
File:
Download Honors_Thesis_FINAL_v2.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

35. CHARACTERIZATION OF ANTICANCER LECTINS AND DEVELOPMENT OF NANOGEL-BASED CARRIERS FOR THEIR TARGETED DELIVERY

open_access
Open Access
Author:
Lawanprasert, Atip
Title:
CHARACTERIZATION OF ANTICANCER LECTINS AND DEVELOPMENT OF NANOGEL-BASED CARRIERS FOR THEIR TARGETED DELIVERY
Area of Honors:
Biomedical Engineering
Keywords:
Lectins
Targeted Delivery
Nanogel
Drug Delivery
Bioresponsive
Anticancer
File:
Download Lawanprasert_Thesis.pdf
Thesis Supervisors:
Scott H Medina, Thesis Supervisor
Jian Yang, Thesis Honors Advisor

36. THE ROLE OF MECHANICALLY GATED ION CHANNELS IN REGULATING THE RESPONSE OF MESENCHYMAL STEM CELLS TO NANOFIBER ARCHITECTURE

open_access
Open Access
Author:
Wandling, Grant Donald
Title:
THE ROLE OF MECHANICALLY GATED ION CHANNELS IN REGULATING THE RESPONSE OF MESENCHYMAL STEM CELLS TO NANOFIBER ARCHITECTURE
Area of Honors:
Biomedical Engineering
Keywords:
Nanofibers
TREK-1
hMSCs
osteoblasts
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

37. DEVELOPMENT OF A NOVEL MAGNESIUM DOPED CITRATE BASED POLYMER COMPOSITE FOR ORTHOPEDIC ENGINEERING

open_access
Open Access
Author:
Rahn, Kevin Michael
Title:
DEVELOPMENT OF A NOVEL MAGNESIUM DOPED CITRATE BASED POLYMER COMPOSITE FOR ORTHOPEDIC ENGINEERING
Area of Honors:
Biomedical Engineering
Keywords:
bone
bone engineering
orthopedic engineering
citrate-based materials
magnesium oxide
polymer
tissue engineering
injection molding
File:
Download Kevin_Rahn_Honors_Thesis.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

38. THE EFFECT OF MICROFIBER MORPHOLOHY AND CELL DENSITY ON THE LOCALIZATION OF YAP PROTEIN IN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Steltz, Austin E
Title:
THE EFFECT OF MICROFIBER MORPHOLOHY AND CELL DENSITY ON THE LOCALIZATION OF YAP PROTEIN IN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
mesenchymal stem cell
msc
YAP
Yes Associated Protein
Mechanotransduction
Transduce
biology
biomedical engineering
electrospinning
fibers
flat
File:
Download Austin_Steltz_thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Yong Wang, Faculty Reader

39. Determining Embolus Trapping Efficiency of an Inferior Vena Cava Filter during Exercise

open_access
Open Access
Author:
Riley, Joshua Mackey
Title:
Determining Embolus Trapping Efficiency of an Inferior Vena Cava Filter during Exercise
Area of Honors:
Biomedical Engineering
Keywords:
Inferior Vena Cava Filter
IVC Filter
Pulmonary Embolism
Trapping Efficiency
File:
Download Riley_Final_Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

40. BLOOD PRESSURE AND ITS EFFECTS ON MUSCLE STIFFNESS MEASUREMENTS THROUGH ULTRASOUND ELASTOGRAPHY

open_access
Open Access
Author:
Johnson, Matthew Bryan
Title:
BLOOD PRESSURE AND ITS EFFECTS ON MUSCLE STIFFNESS MEASUREMENTS THROUGH ULTRASOUND ELASTOGRAPHY
Area of Honors:
Biomedical Engineering
Keywords:
Compartment Syndrome
Blood Pressure
Ultrasound
Shear Wave Elastography
Intramuscular Pressure
Muscle Stiffness
File:
Download FINAL_THESIS.pdf
Thesis Supervisors:
Dr. Daniel Humberto Cortes Correales, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor
Meghan Elise Vidt, Faculty Reader

41. INVESTIGATING SENSORY AND MOTOR DIFFERENCES IN VARYING FORCE OUTPUT IN YOUNG ADULTS WITH AND WITHOUT ADHD

open_access
Open Access
Author:
Tucker, Jacqueline Rose
Title:
INVESTIGATING SENSORY AND MOTOR DIFFERENCES IN VARYING FORCE OUTPUT IN YOUNG ADULTS WITH AND WITHOUT ADHD
Area of Honors:
Biomedical Engineering
Keywords:
grip force
motor control
sensory
tactile
attention deficit hyperactivity disorder (ADHD)
File:
Download Jacqueline_Tucker_Thesis.pdf
Thesis Supervisors:
Kristina A Neely, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Meghan Elise Vidt, Faculty Reader

46. Evaluation of poly(octamethylene citrate glycerophosphate) for enhanced cell differentiation and bone regeneration

open_access
Open Access
Author:
Chomos, Sarah Katherine
Title:
Evaluation of poly(octamethylene citrate glycerophosphate) for enhanced cell differentiation and bone regeneration
Area of Honors:
Biomedical Engineering
Keywords:
citrate-based biomaterials
glycerophosphate
osteogenic differentiation
File:
Download SarahChomos_FinalThesis.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor

50. Studying Thrombosis and Surface Roughness in the Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Richardsen, Cecilia
Title:
Studying Thrombosis and Surface Roughness in the Penn State Pediatric Ventricular Assist Device
Area of Honors:
Biomedical Engineering
Keywords:
thrombosis
heart
surface roughness
bridge to transplant
PVAD
artificial organ
polyurethane
platelets
fibrin
File:
Download Richardsen_Thesis_Final_SHC_.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Justin Lee Brown, Thesis Honors Advisor