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Start Over Area of Honors Biomedical Engineering

1. Targeted Sequencing Of Chromosome 9 Genes Associated With Papillary Type 1 Renal Cell Carcinoma

open_access
Open Access
Author:
Belsky, Michael Alan
Title:
Targeted Sequencing Of Chromosome 9 Genes Associated With Papillary Type 1 Renal Cell Carcinoma
Area of Honors:
Biomedical Engineering
Keywords:
Cancer
next generation sequencing
renal cell carcinoma
targeted sequencing
papillary type 1
File:
Download Belsky_Thesis_Final.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William A La Framboise, Faculty Reader

4. The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells

open_access
Open Access
Author:
Porter, Michael John
Title:
The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells
Area of Honors:
Biomedical Engineering
Keywords:
Nanoparticle
Nanoparticles
IL-13
Interleukin
Glioma
GBM
Glioblastoma multiforme
conjugated
computational
kinetics
File:
Download Final_Thesis_Porter.pdf
Thesis Supervisors:
Sheereen Majd, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Herbert Herling Lipowsky, Faculty Reader

5. THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Mcculloch, Mary Elizabeth
Title:
THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
FAK
SRC
Tissue Engineering
hMSCs
migration
Focal adhesions
File:
Download HonorsFINALThesisDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

8. Membrane Microdomains Regulate Focal Adhesion Size in Bovine Aortic Endothelial Cells

open_access
Open Access
Author:
Culver, Margaret Frances
Title:
Membrane Microdomains Regulate Focal Adhesion Size in Bovine Aortic Endothelial Cells
Area of Honors:
Biomedical Engineering
Keywords:
Focal Adhesion
Lipid Rafts
Non-lipid amphiphiles
File:
Download Final_Thesis_for_submission_pdf.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

9. An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells

open_access
Open Access
Author:
Swatski, Matthew David
Title:
An Investigation Into The Nanofiber-induced Epigenetic Changes In Mesenchymal Stem Cells
Area of Honors:
Biomedical Engineering
Keywords:
epigenetics
nanofibers
PMMA
biomaterials
regenerative medicine
stem cells
tissue engineering
biomedical engineering
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Jian Yang, Faculty Reader

11. Melanoma Extravasation Through the Endothelium Affects Focal Adhesion Disassembly

open_access
Open Access
Author:
Eswar, Vikram Jayraj
Title:
Melanoma Extravasation Through the Endothelium Affects Focal Adhesion Disassembly
Area of Honors:
Biomedical Engineering
Keywords:
melanoma
Src
focal adhesion
endothelium
traction force
vinculin
contractility
extravasation
File:
Download Eswar_Thesis.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Esther Winter Gomez, Faculty Reader

13. Impact of Pulsatility and Flow Rates on Hemodynamic Energy Transmission in an Adult ECLS System

open_access
Open Access
Author:
Wolfe, Rachel Morgan
Title:
Impact of Pulsatility and Flow Rates on Hemodynamic Energy Transmission in an Adult ECLS System
Area of Honors:
Biomedical Engineering
Keywords:
Extracorporeal life support
Diagonal pump
XLung oxygenator
Adult
Pulsatile flow
Extracorporeal life support
Diagonal pump
XLung oxygenator
Adult
Pulsatile flow
File:
Download WolfeRachel_FinalThesisPDF.pdf
Thesis Supervisors:
Akif Undar, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor

14. Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides

open_access
Open Access
Author:
Lingafelt, Colin Mark
Title:
Determining the Effect of Kinesin-5 Inhibitors on the Nucleation Rates of Microtubules in vitro and Synthesizing, Characterizing, and Purifying Fluorescently Labeled Nucleotides
Area of Honors:
Biomedical Engineering
Keywords:
kinesins
microtubules
fluorescent nucleotides
binding rates
synthesis
Eg5
nucleation
tubulin
critical concentration
File:
Download thesis_ColinLingafelt_04102017_final.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader
Herbert Herling Lipowsky, Faculty Reader

15. RELATIONSHIP OF PLATELET ADHESION WITH SURFACE TOPOGRAPHY IN THE PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE

open_access
Open Access
Author:
Mueser, Ashlyn S
Title:
RELATIONSHIP OF PLATELET ADHESION WITH SURFACE TOPOGRAPHY IN THE PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE
Area of Honors:
Biomedical Engineering
Keywords:
PVAD
Platelet Adhesion
Surface Topography
Pediatric Ventricular Assist Devices
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

16. VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL

open_access
Open Access
Author:
McKellar, Brian U
Title:
VISUALIZATION AND QUANTITATION OF STEM CELL MEDIATED MINERALIZATION OF A DEMINERALIZED COLLAGEN SAFFOLD IN A TISSUE ENGINEERING MODEL
Area of Honors:
Biomedical Engineering
Keywords:
Tissue Engineering
Bone
Biomineralization
Osteogenic differentiation
Stem cell
File:
Download McKellar_EpiBone_Thesis_FinalSchreyer_links.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

18. The impact of genetic variants on kinesin motor proteins and the link to neurological disorders

open_access
Open Access
Author:
Erdman, Marcus Orion
Title:
The impact of genetic variants on kinesin motor proteins and the link to neurological disorders
Area of Honors:
Biomedical Engineering
Keywords:
kinesin
neurological disorder
mutation
genomics
File:
Download Thesis_final_Marcus_Erdman.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Dr. Justin Lee Brown, Faculty Reader

19. A Study of the Effect of Hematocrit on Weaning in the 12 cc Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Gallagher, Maureen Brenna
Title:
A Study of the Effect of Hematocrit on Weaning in the 12 cc Penn State Pediatric Ventricular Assist Device
Area of Honors:
Biomedical Engineering
Keywords:
PVAD
artificial heart
hematocrit
weaning
fluid dynamics
File:
Download Gallagher_Schreyer_Thesis_FINAL.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader
Dr. William O Hancock, Faculty Reader

20. Design, construction, and testing of a pneumatic vibrotactile stimulus system for use with awake, behaving mice

open_access
Open Access
Author:
Cook, Alexander Philip
Title:
Design, construction, and testing of a pneumatic vibrotactile stimulus system for use with awake, behaving mice
Area of Honors:
Biomedical Engineering
Keywords:
Neurovascular coupling
Electrophysiology
Passive touch
Pneumatic system
Vibrotactile stimulus
File:
Download Cook_Alexander_PneumaticSystem.pdf
Thesis Supervisors:
Patrick James Drew, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Nanyin Zhang, Faculty Reader

21. Pulsatile Assessment Of The FDA Computational Study Of Fluid Flow In Biomedical Devices

open_access
Open Access
Author:
Kessler, Joshua C
Title:
Pulsatile Assessment Of The FDA Computational Study Of Fluid Flow In Biomedical Devices
Area of Honors:
Biomedical Engineering
Keywords:
FDA
Turbulence
Computational Fluid Dynamics
CFD
LDV
Benchmark Nozzle Model
Critical Path Initiative
Pulsatile Flow
File:
Download Thesisv_schreyer.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Pak Kin Wong, Faculty Reader

22. CHARACTERIZATION OF THROMBI THROUGH MRI AND HISTOLOGICAL ANALYSIS OF ERYTHROCYTE GHOST CLOTS

open_access
Open Access
Author:
Hagenah, Kristen E
Title:
CHARACTERIZATION OF THROMBI THROUGH MRI AND HISTOLOGICAL ANALYSIS OF ERYTHROCYTE GHOST CLOTS
Area of Honors:
Biomedical Engineering
Keywords:
Ghost Cells
Quantitative Susceptibility Mapping
Left Ventricular Thrombus
File:
Download Hagenah_Kristen_Schreyer_Thesis_Final_.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

23. CALCIUM DOPED CITRATE BOUND BIOMATERIALS FOR MULTIFUNCTIONAL ORTHOPEDIC TISSUE ENGINEERING APPLICATIONS

open_access
Open Access
Author:
Fadel, John Elias
Title:
CALCIUM DOPED CITRATE BOUND BIOMATERIALS FOR MULTIFUNCTIONAL ORTHOPEDIC TISSUE ENGINEERING APPLICATIONS
Area of Honors:
Biomedical Engineering
Keywords:
Bone
orthopedics
orthopedic engineering
tissue engineering
bone implant
polymer
polymer engineering
characterization
materials
File:
Download Final_Thesis_Draft_FADEL.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

24. A CONTROL STUDY USING DNA TO TEST THE EFFECTS OF SHEAR STRESS ON VON WILLEBRAND FACTOR

open_access
Open Access
Author:
Jankowska, Maya Ann-Marie
Title:
A CONTROL STUDY USING DNA TO TEST THE EFFECTS OF SHEAR STRESS ON VON WILLEBRAND FACTOR
Area of Honors:
Biomedical Engineering
Keywords:
von willebrand factor
vwf
optical trap
fluid shear
LVADS
plasmid
fluid mechanics
optical tweezers
shear stress
acquired von willebrand syndrome
File:
Download vWF_Thesis_wTemplate_Maya2.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

28. SYNTHESIS AND EFFECTS OF A PHOTOACTIVATED SILVER NANOPARTICLE PLATFORM DELIVERING MIR-148B IN LUNG ADENOCARCINOMA

open_access
Open Access
Author:
Chan, Alexander
Title:
SYNTHESIS AND EFFECTS OF A PHOTOACTIVATED SILVER NANOPARTICLE PLATFORM DELIVERING MIR-148B IN LUNG ADENOCARCINOMA
Area of Honors:
Biomedical Engineering
Keywords:
cancer
lung cancer
silver
silver nanoparticles
nanoparticles
theranostics
siRNA
miRNA
photothermal
File:
Download Chan_final_thesis.pdf
Thesis Supervisors:
Daniel J Hayes, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Scott H Medina, Faculty Reader

29. THE FUNCTIONAL CONNECTIVITY CHANGES IN THE RAT BRAIN FOLLOWING ACUTE AND CHRONIC NICOTINE ADMINISTRATION

open_access
Open Access
Author:
Roby, Alison C
Title:
THE FUNCTIONAL CONNECTIVITY CHANGES IN THE RAT BRAIN FOLLOWING ACUTE AND CHRONIC NICOTINE ADMINISTRATION
Area of Honors:
Biomedical Engineering
Keywords:
functional connectivity
nicotine
individual difference
acute response
File:
Download thesis_Roby_Alison_final_links.pdf
Thesis Supervisors:
Dr. Nanyin Zhang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

30. EXPERIMENTAL PLATFORM SIMULATING THE MECHANICAL EFFECTS OF DIAPHRAGMATIC MOTION ON INFERIOR VENA CAVA COLLAPSIBILITY

open_access
Open Access
Author:
Crompton, Philip Edward
Title:
EXPERIMENTAL PLATFORM SIMULATING THE MECHANICAL EFFECTS OF DIAPHRAGMATIC MOTION ON INFERIOR VENA CAVA COLLAPSIBILITY
Area of Honors:
Biomedical Engineering
Keywords:
IVC filter
IVC collapse
diaphragmatic motion
inferior vena cava
File:
Download Crompton_Thesis2.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Justin Lee Brown, Thesis Honors Advisor

31. Assessment of Demographic, Anthropometric, and Physical Performance Variables As Predictors of Sprint Cycling Power

open_access
Open Access
Author:
Mellen, James Scott
Title:
Assessment of Demographic, Anthropometric, and Physical Performance Variables As Predictors of Sprint Cycling Power
Area of Honors:
Biomedical Engineering
Keywords:
cycling
vertical jump
wearable measurement device
sprint
File:
Download James_Mellen_Thesis_Final_Draft__3-30-18_.pdf
Thesis Supervisors:
Giampietro Luciano Vairo, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

32. Investigating the Impact of Flow Recirculation on Cellular Uptake of Nanoparticles

open_access
Open Access
Author:
Boland, Samuel Fares
Title:
Investigating the Impact of Flow Recirculation on Cellular Uptake of Nanoparticles
Area of Honors:
Biomedical Engineering
Keywords:
nanoparticles
atherosclerosis
flow chamber
finite element analysis
drug delivery
fluid dynamics
cell mechanics
File:
Download Boland_Thesis_Final.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Dr. Justin Lee Brown, Thesis Honors Advisor

33. THE EFFECTS OF CELL MORPHOLOGY ON NANOPARTICLE UPTAKE AND UPTAKE AT THE LEADING EDGE IN MC3T3 CELLS

open_access
Open Access
Author:
Li, Harvey S
Title:
THE EFFECTS OF CELL MORPHOLOGY ON NANOPARTICLE UPTAKE AND UPTAKE AT THE LEADING EDGE IN MC3T3 CELLS
Area of Honors:
Biomedical Engineering
Keywords:
Biomedical engineering
cell morphology
cell culture
microcontact printing
immunostaining
immunofluorescence
live-cell imaging
cell leading edge
cell
y-27632
File:
Download Honors_Thesis_FINAL_v2.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

35. CHARACTERIZATION OF ANTICANCER LECTINS AND DEVELOPMENT OF NANOGEL-BASED CARRIERS FOR THEIR TARGETED DELIVERY

open_access
Open Access
Author:
Lawanprasert, Atip
Title:
CHARACTERIZATION OF ANTICANCER LECTINS AND DEVELOPMENT OF NANOGEL-BASED CARRIERS FOR THEIR TARGETED DELIVERY
Area of Honors:
Biomedical Engineering
Keywords:
Lectins
Targeted Delivery
Nanogel
Drug Delivery
Bioresponsive
Anticancer
File:
Download Lawanprasert_Thesis.pdf
Thesis Supervisors:
Scott H Medina, Thesis Supervisor
Jian Yang, Thesis Honors Advisor

36. THE ROLE OF MECHANICALLY GATED ION CHANNELS IN REGULATING THE RESPONSE OF MESENCHYMAL STEM CELLS TO NANOFIBER ARCHITECTURE

open_access
Open Access
Author:
Wandling, Grant Donald
Title:
THE ROLE OF MECHANICALLY GATED ION CHANNELS IN REGULATING THE RESPONSE OF MESENCHYMAL STEM CELLS TO NANOFIBER ARCHITECTURE
Area of Honors:
Biomedical Engineering
Keywords:
Nanofibers
TREK-1
hMSCs
osteoblasts
File:
Download Thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

37. DEVELOPMENT OF A NOVEL MAGNESIUM DOPED CITRATE BASED POLYMER COMPOSITE FOR ORTHOPEDIC ENGINEERING

open_access
Open Access
Author:
Rahn, Kevin Michael
Title:
DEVELOPMENT OF A NOVEL MAGNESIUM DOPED CITRATE BASED POLYMER COMPOSITE FOR ORTHOPEDIC ENGINEERING
Area of Honors:
Biomedical Engineering
Keywords:
bone
bone engineering
orthopedic engineering
citrate-based materials
magnesium oxide
polymer
tissue engineering
injection molding
File:
Download Kevin_Rahn_Honors_Thesis.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

38. THE EFFECT OF MICROFIBER MORPHOLOHY AND CELL DENSITY ON THE LOCALIZATION OF YAP PROTEIN IN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Steltz, Austin E
Title:
THE EFFECT OF MICROFIBER MORPHOLOHY AND CELL DENSITY ON THE LOCALIZATION OF YAP PROTEIN IN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
mesenchymal stem cell
msc
YAP
Yes Associated Protein
Mechanotransduction
Transduce
biology
biomedical engineering
electrospinning
fibers
flat
File:
Download Austin_Steltz_thesis.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Yong Wang, Faculty Reader

39. Determining Embolus Trapping Efficiency of an Inferior Vena Cava Filter during Exercise

open_access
Open Access
Author:
Riley, Joshua Mackey
Title:
Determining Embolus Trapping Efficiency of an Inferior Vena Cava Filter during Exercise
Area of Honors:
Biomedical Engineering
Keywords:
Inferior Vena Cava Filter
IVC Filter
Pulmonary Embolism
Trapping Efficiency
File:
Download Riley_Final_Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

40. BLOOD PRESSURE AND ITS EFFECTS ON MUSCLE STIFFNESS MEASUREMENTS THROUGH ULTRASOUND ELASTOGRAPHY

open_access
Open Access
Author:
Johnson, Matthew Bryan
Title:
BLOOD PRESSURE AND ITS EFFECTS ON MUSCLE STIFFNESS MEASUREMENTS THROUGH ULTRASOUND ELASTOGRAPHY
Area of Honors:
Biomedical Engineering
Keywords:
Compartment Syndrome
Blood Pressure
Ultrasound
Shear Wave Elastography
Intramuscular Pressure
Muscle Stiffness
File:
Download FINAL_THESIS.pdf
Thesis Supervisors:
Dr. Daniel Humberto Cortes Correales, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor
Meghan Elise Vidt, Faculty Reader

41. INVESTIGATING SENSORY AND MOTOR DIFFERENCES IN VARYING FORCE OUTPUT IN YOUNG ADULTS WITH AND WITHOUT ADHD

open_access
Open Access
Author:
Tucker, Jacqueline Rose
Title:
INVESTIGATING SENSORY AND MOTOR DIFFERENCES IN VARYING FORCE OUTPUT IN YOUNG ADULTS WITH AND WITHOUT ADHD
Area of Honors:
Biomedical Engineering
Keywords:
grip force
motor control
sensory
tactile
attention deficit hyperactivity disorder (ADHD)
File:
Download Jacqueline_Tucker_Thesis.pdf
Thesis Supervisors:
Kristina A Neely, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Meghan Elise Vidt, Faculty Reader

46. Evaluation of poly(octamethylene citrate glycerophosphate) for enhanced cell differentiation and bone regeneration

open_access
Open Access
Author:
Chomos, Sarah Katherine
Title:
Evaluation of poly(octamethylene citrate glycerophosphate) for enhanced cell differentiation and bone regeneration
Area of Honors:
Biomedical Engineering
Keywords:
citrate-based biomaterials
glycerophosphate
osteogenic differentiation
File:
Download SarahChomos_FinalThesis.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor

50. Studying Thrombosis and Surface Roughness in the Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Richardsen, Cecilia
Title:
Studying Thrombosis and Surface Roughness in the Penn State Pediatric Ventricular Assist Device
Area of Honors:
Biomedical Engineering
Keywords:
thrombosis
heart
surface roughness
bridge to transplant
PVAD
artificial organ
polyurethane
platelets
fibrin
File:
Download Richardsen_Thesis_Final_SHC_.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Justin Lee Brown, Thesis Honors Advisor

52. THE ROLE OF CLC-3 CHLORIDE CHANNELS IN THE PROGRESSION OF THE 5XFAD ALZHEIMER’S DISEASE MOUSE MODEL

open_access
Open Access
Author:
Parry, Matthew
Title:
THE ROLE OF CLC-3 CHLORIDE CHANNELS IN THE PROGRESSION OF THE 5XFAD ALZHEIMER’S DISEASE MOUSE MODEL
Area of Honors:
Biomedical Engineering
Keywords:
CLC-3
Chloride Channels
Alzheimer's disease
Amyloid Beta
Aβ42
β-secretase
Beta Secretase
BACE1
File:
Download thesis_formatted_Honors.pdf
Thesis Supervisors:
Dr. Gong Chen, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Kevin Douglas Alloway, Thesis Honors Advisor

53. Fabrication of Biphasic Bone Scaffolds with Highly Connected Inner Porosity and Biomimetic Composition for Regeneration in Large, Load-Bearing Defects

open_access
Open Access
Author:
Hudock, Maria
Title:
Fabrication of Biphasic Bone Scaffolds with Highly Connected Inner Porosity and Biomimetic Composition for Regeneration in Large, Load-Bearing Defects
Area of Honors:
Biomedical Engineering
Keywords:
bone scaffold
osteoconductivity
freeze casting
BPLP-PSer
Pelodiscus sinensis collagen
large segmental defect
File:
Download biphasic_BPLP-PSer_TC_bone_scaffolds_MH.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Dr. Xiaojun Lance Lian, Faculty Reader
Cheng Dong, Faculty Reader

54. SURFACE CHARACTERISTICS OF IMPLANTABLE LONG-TERM USE FONTAN PUMP MATERIALS

open_access
Open Access
Author:
Mc Hugh, Clare Moire
Title:
SURFACE CHARACTERISTICS OF IMPLANTABLE LONG-TERM USE FONTAN PUMP MATERIALS
Area of Honors:
Biomedical Engineering
Keywords:
Biomaterials
Biomedical Engineering
Fontan Circulation
Fluid Mechanics
Biocompatibility
Platelet Adhesion
Thrombosis
Medical Device
File:
Download McHugh_Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Justin Lee Brown, Thesis Honors Advisor

55. Determining the Efficiency of Emboli Detection with Ultrasonography

open_access
Open Access
Author:
Pearson, Cara Emily
Title:
Determining the Efficiency of Emboli Detection with Ultrasonography
Area of Honors:
Biomedical Engineering
Keywords:
Cardiovascular Fluid Dynamics
Ultrasound
Emboli
Pulmonary Embolism
Pan-Tompkins Algorithm
Doppler Effect
High Intensity Transient Signals
Thrombus
Reynolds number
Blood
Hemostasis
Coagulation Cascade
Ultrasonography
Heart Attack
Stroke
Artificial Heart
File:
Download Pearson_Cara_Thesis2019.docx.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor

57. Yes-associated protein 1 localization in response to substrate architecture

open_access
Open Access
Author:
Chan, Coreena
Title:
Yes-associated protein 1 localization in response to substrate architecture
Area of Honors:
Biomedical Engineering
Keywords:
YAP
YAP1
yes-associated protein
yes-associated protein 1
nanofibers
osteogenesis
osteogenic differentiation
RhoA
FAK
focal adhesions
tissue engineering
Hippo signaling pathway
cancer
tumor suppression
File:
Download Chan_Coreena_Honors_Thesis_SP19.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Timothy J Jegla, Thesis Honors Advisor

58. Brownian Dynamics Simulation of Kinesin

open_access
Open Access
Author:
Cook, Zeke
Title:
Brownian Dynamics Simulation of Kinesin
Area of Honors:
Biomedical Engineering
Keywords:
Kinesin
Protein
Motor
Mechanobiology
Mechanochemistry
Processive
Fluorescence
Gold Nanoparticle
Tracking
Total Internal Reflection
Microscopy
Interferometric Scattering
Brownian
Dynamics
Brownian Dynamics
Molecular Modeling
Molecular Dynamics
File:
Download Cook_Annan_BrownianDynamicsSimulationofKinesinMotorProteinDynamics.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

59. The Effect of Lamin A/C and the LINC Complex on TGFβ1-Induced Epithelial to Mesenchymal Transition

open_access
Open Access
Author:
Ling, Melissa
Title:
The Effect of Lamin A/C and the LINC Complex on TGFβ1-Induced Epithelial to Mesenchymal Transition
Area of Honors:
Biomedical Engineering
Keywords:
Epithelial-Mesenchymal Transition
Lamin A/C
TGFβ1
LINC Complex
SUN2
Nuclear Mechanotransduction
File:
Download Final_Thesis_Draft_2020-05-11_Ling.pdf
Thesis Supervisors:
Esther Winter Gomez, Thesis Supervisor
Dr. Nanyin Zhang, Thesis Honors Advisor
Spencer Szczesny, Faculty Reader

61. Analyzing Calcium Deposition on Titanium Surfaces

open_access
Open Access
Author:
Shah, Vraj
Title:
Analyzing Calcium Deposition on Titanium Surfaces
Area of Honors:
Biomedical Engineering
Keywords:
Calcium Deposition
Roughened Titanium Surfaces
Osteogenic Regeneration
Macro-micro textured surface (MM)
Macro-micro-nano textured surface (MMN)
Vraj Shah
File:
Download Analyzing_Calcium_Deposiiton_on_TItanium_Surfaces_ShahVraj.pdf
Thesis Supervisors:
Justin Lee Brown, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Sarah C Ritter, Faculty Reader

62. A Study of the Effect of Hematocrit on an Elevated Beat Rate in the 12cc Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Houtz, Brady
Title:
A Study of the Effect of Hematocrit on an Elevated Beat Rate in the 12cc Penn State Pediatric Ventricular Assist Device
Area of Honors:
Biomedical Engineering
Keywords:
PVAD
artificial heart
cardiovascular
fluid dynamics
beat rate
hematocrit
File:
Download Houtz_SchreyerThesis.pdf
Thesis Supervisors:
Keefe B Manning, Thesis Supervisor
William O Hancock, Thesis Honors Advisor
William Joseph Weiss, Faculty Reader

64. Antimicrobial Peptide Aerogels As An Inhalable Therapy For Drug-Resistant Tuberculosis

open_access
Open Access
Author:
Klein, Bailey
Title:
Antimicrobial Peptide Aerogels As An Inhalable Therapy For Drug-Resistant Tuberculosis
Area of Honors:
Biomedical Engineering
Keywords:
Antimicrobial Peptides
Aerogels
Peptides
Tubercuosis
Mycobacterium Tuberculosis
File:
Download Final_Klein_Thesis.pdf
Thesis Supervisors:
Scott H Medina, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Justin Lee Brown, Faculty Reader

65. Development of an in vitro culture and loading protocol to study the mechanobiology of rabbit anterior cruciate ligaments

open_access
Open Access
Author:
Carrozzi, Sabrina
Title:
Development of an in vitro culture and loading protocol to study the mechanobiology of rabbit anterior cruciate ligaments
Area of Honors:
Biomedical Engineering
Keywords:
anterior cruciate ligament
ACL
mechanobiology
ligament
tendon
allograft
autograft
biomechanics
File:
Download Final_Schreyer_Thesis.pdf
Thesis Supervisors:
Spencer Szczesny, Thesis Supervisor
William O Hancock, Thesis Honors Advisor

66. Engineering Biomimetic Anticancer Therapies

open_access
Open Access
Author:
Aronson, Matthew
Title:
Engineering Biomimetic Anticancer Therapies
Area of Honors:
Biomedical Engineering
Keywords:
De novo design
anticancer peptides
supramolecular assembly
nanostructures
combinatorial therapy
de novo design
anticancer peptides
supramolecular assembly
nanostructures
combinatorial therapy
drug delivery
nanomedicine
File:
Download Aronson_Thesis_Final.pdf
Thesis Supervisors:
Scott H Medina, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Deb Kelly, Faculty Reader

67. Building 3D Structural Density Maps of p53 Obtained From U-87 MG Glioblastoma Cell Line

open_access
Open Access
Author:
Evans, Madison
Title:
Building 3D Structural Density Maps of p53 Obtained From U-87 MG Glioblastoma Cell Line
Area of Honors:
Biomedical Engineering
Keywords:
p53 tetramer
p53 dimer
Glioblastoma Multiforme cancer
protein structural construction
cryo-EM
negative staining
TEM.
p53 tetramer
p53 dimer
Glioblastoma Multiforme (GBM) cancer
protein structural construction
cryo-EM
negative staining
TEM
File:
Download Evans_Madison_Building_3D_Structural_Density_Maps_of_p53_Obtained_From_U87_MG_GBM_Cell_Line.pdf
Thesis Supervisors:
Deb Kelly, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor

68. Modeling the Dynamics of Elk Subfamily Ion Channels for Physiological Modulation

open_access
Open Access
Author:
Deal, Jack
Title:
Modeling the Dynamics of Elk Subfamily Ion Channels for Physiological Modulation
Area of Honors:
Biomedical Engineering
Keywords:
Elk
Voltage-Gated Ion Channels
Heme
Kinetic Model
Axon Initial Segment
Gating Mechanism
Boltzmann
Affinity
Drosophila melanogaster
Ankyrin
Fluorescent Microscopy
Xenopus
Potassium Channels
File:
Download Jack_Deal_Modeling_the_Dynamics_of_Elk_Subfamily_Ion_Channels_for_Physiological_Modulation.pdf
Thesis Supervisors:
Timothy J Jegla, Thesis Supervisor
William O Hancock, Thesis Honors Advisor

72. Commensal Biocapsules as a Bacterial Delivery System to Reengineer the Microbiome

open_access
Open Access
Author:
Ali, Yasmin
Title:
Commensal Biocapsules as a Bacterial Delivery System to Reengineer the Microbiome
Area of Honors:
Biomedical Engineering
Keywords:
biomaterials
microbiome engineering
precision therapy
drug delivery
antimicrobial peptides
gastrointestinal disease
File:
Download Undergraduate_Thesis_-_Yasmin_Ali.pdf
Thesis Supervisors:
Scott H Medina, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor

73. The Effect of Nanofiber Size and Orientation on Human Mesenchymal Stem Cell Nuclear Lamina Composition

open_access
Open Access
Author:
Riggio, Abby
Title:
The Effect of Nanofiber Size and Orientation on Human Mesenchymal Stem Cell Nuclear Lamina Composition
Area of Honors:
Biomedical Engineering
Keywords:
hMSCs
Nuclear Lamina
Phosphorylation
Stem Cell Engineering
PMMA
Nanofibers
File:
Download RiggioThesisFinal.pdf
Thesis Supervisors:
Justin Lee Brown, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor
Daniel J Hayes, Faculty Reader

74. Experimental and Computational Investigation of Correlates of Diffusion Tensor Imaging Changes and Mechanical Strain

open_access
Open Access
Author:
Aklilu, Ouniol
Title:
Experimental and Computational Investigation of Correlates of Diffusion Tensor Imaging Changes and Mechanical Strain
Area of Honors:
Biomedical Engineering
Keywords:
Fractional Anisotropy
White Matter Tissue
Traumatic Brain Injury
File:
Download Aklilu_Ouniol_Senior__Thesis_edited.pdf
Thesis Supervisors:
Reuben H Kraft, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor
Nanyin Zhang, Faculty Reader

76. An Exploration of Ancient Kinases and a Meta-Analysis of the Modern Use of Tyrosine Kinase Inhibitors in the Literature

open_access
Open Access
Author:
Abello, Kerry
Title:
An Exploration of Ancient Kinases and a Meta-Analysis of the Modern Use of Tyrosine Kinase Inhibitors in the Literature
Area of Honors:
Biomedical Engineering
Keywords:
Kinases
Tyrosine Kinases
Src
Abl
Cancer
Tyrosine Kinase Inhibitor
Imatinib
Pharmacokinetics
Serum Binding
Protein Binding
File:
Download Abello_Kerry_An_Exploration_of_Ancient_Kinases_and_a_Meta-Analysis_of_the_Modern_Use_of_Tyrosine_Kinase_Inhibitors_in_the_Literature.pdf
Thesis Supervisors:
Justin R Pritchard, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor

77. Analytical Modeling Study of Acute Lymphoblastic Leukemia Treatment with Blinatumomab and Tyrosine Kinase Inhibitors

open_access
Open Access
Author:
Onweller, Lauren
Title:
Analytical Modeling Study of Acute Lymphoblastic Leukemia Treatment with Blinatumomab and Tyrosine Kinase Inhibitors
Area of Honors:
Biomedical Engineering
Keywords:
TKI
BiTE
Cancer
Combination Therapy
Matlab
File:
Download Analytical_Modeling_Study_of_Acute_Lymphoblastic_Leukemia_Treatment_with_Blinatumomab_and_Tyrosine_Kinase_Inhibitors.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Meghan Vidt, Thesis Honors Advisor
Justin R Pritchard, Thesis Supervisor

78. Assessing the Degradation of Novel Neural Prostheses Using Real Time Shear Wave Elastography, Ultrasound, and Photoacoustic Imaging Tools

open_access
Open Access
Author:
Drozynski, Hanna
Title:
Assessing the Degradation of Novel Neural Prostheses Using Real Time Shear Wave Elastography, Ultrasound, and Photoacoustic Imaging Tools
Area of Honors:
Biomedical Engineering
Keywords:
Shear Wave Elastography
Ultrasound
Photoacoustic
Medical Imaging
Neural Protheses
Biomaterials
Shear Modulus
File:
Download Honors_Thesis.pdf
Thesis Supervisors:
Sri-Rajasekhar Kothapalli, Thesis Supervisor
Meghan Vidt, Thesis Honors Advisor

79. Stochastic Simulations of Tumor Progression Under Targeted Therapy Suggest a Tradeoff Between Evolutionary Trajectories

open_access
Open Access
Author:
Liu, Mengde
Title:
Stochastic Simulations of Tumor Progression Under Targeted Therapy Suggest a Tradeoff Between Evolutionary Trajectories
Area of Honors:
Biomedical Engineering
Keywords:
Cancer
Biomedical Engineering
Computational Modeling
File:
Download Thesis_MLiu041222.pdf
Thesis Supervisors:
Justin R Pritchard, Thesis Supervisor
Jian Yang, Thesis Honors Advisor

81. Long-Term Rates of Congenital Cytomegalovirus Sequelae; A Systematic Review and Meta-Analysis of Congenital Cytomegalovirus

open_access
Open Access
Author:
Roach, Mikayla
Title:
Long-Term Rates of Congenital Cytomegalovirus Sequelae; A Systematic Review and Meta-Analysis of Congenital Cytomegalovirus
Area of Honors:
Biomedical Engineering
Keywords:
Cytomegalovirus
Congenital
Infection
Prevalance
Sequelae
File:
Download Roach_Mikayla_Thesis.pdf
Thesis Supervisors:
James Riley Broach, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor

83. Engineering Molecular Sensors for The Detection of SOX9, RUNX2, and PPARG Transcription Factors

open_access
Open Access
Author:
Pera Mendes, Joao Paulo
Title:
Engineering Molecular Sensors for The Detection of SOX9, RUNX2, and PPARG Transcription Factors
Area of Honors:
Biomedical Engineering
Keywords:
Nanosensor
Transcription Factor
DNA
Probe
SOX9
RUNX2
PPARG
FRET
iPSC
Molecular
Sensor
GNR
File:
Download FinalThesis_JoaoPauloPeraMendes.pdf
Thesis Supervisors:
Pak Kin Wong, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Daniel J Hayes, Faculty Reader

87. Implementation of Hygienic Products and Medical Systems in Developing Countries

open_access
Open Access
Author:
Gibbard, Sydney
Title:
Implementation of Hygienic Products and Medical Systems in Developing Countries
Area of Honors:
Biomedical Engineering
Keywords:
Menstrual products
Developing Countries
Medicine
Menstruation
Biomedical Engineering
Humanitarian Engineering
Refugees
Women Equality
Women's Rights
Period Poverty
File:
Download Sydney_Gibbard_Thesis_Spring_23.pdf
Thesis Supervisors:
John Gershenson, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor

88. An In Vitro Wound Healing Model Evaluating Zinc Supplementation with Synthetic Wound Dressings

open_access
Open Access
Author:
Snow, Emily
Title:
An In Vitro Wound Healing Model Evaluating Zinc Supplementation with Synthetic Wound Dressings
Area of Honors:
Biomedical Engineering
Keywords:
Wound Healing
Tissue Engineering
Stem Cells
Zinc
Nutrient Supplementation
Nanofiber Scaffolds
HEK293
Cell Proliferation
Cytokine Secretion
Cell Migration
File:
Download Emily_Snow_Final_Thesis.pdf
Thesis Supervisors:
Justin Lee Brown, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor
Peter Butler, Faculty Reader
Maria Rita Castro, Faculty Reader

89. Developing A Wound-Assay for Modeling Collective Cell Migration In Vitro

open_access
Open Access
Author:
Narayanamangalam, Aryath
Title:
Developing A Wound-Assay for Modeling Collective Cell Migration In Vitro
Area of Honors:
Biomedical Engineering
Keywords:
Collective Cell Migration
Wound Healing
Wound Assay
Scratch Assay
Nanofibers
Biomaterials
Cell Migration
Cancer Metastasis
Electrospinning
Stereolithography
3D Printing
File:
Download Developing_A_Wound-Assay_for_Modeling_Collective_Cell_Migration_In-Vitro_FINAL.pdf
Thesis Supervisors:
Justin Lee Brown, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor
Pak Kin Wong, Faculty Reader

93. A Flow Study of the Effects of Outlet Valve Angle in the Right Side of the 12cc Penn State Pediatric Total Artificial Heart

restricted_to_institution
Restricted (Penn State Only)
Author:
Selinsky, Peter
Title:
A Flow Study of the Effects of Outlet Valve Angle in the Right Side of the 12cc Penn State Pediatric Total Artificial Heart
Area of Honors:
Biomedical Engineering
Keywords:
Penn State
Particle image velocimetry (PIV)
pediatric ventricular assist device (PVAD)
total artificial heart (TAH)
ventricular assist device (VAD)
pediatric total artificial heart (pTAH)
right side of pediatric total artificial heart (RpTAH)
fluid dynamics
blood analog
mechanical circulatory support device (MCSD)
outlet valve angle
3D flow
rotational flow
wall washing
fluid velocity
flow loop
File:
Login to Download
Thesis Supervisors:
Keefe B Manning, Thesis Supervisor
Nanyin Zhang, Thesis Honors Advisor
William Joseph Weiss, Faculty Reader

94. Model Development and Analysis of the Rat Supraspinatus Muscle-Tendon-Bone Unit

restricted_to_institution
Restricted (Penn State Only)
Author:
Cush, Coleman
Title:
Model Development and Analysis of the Rat Supraspinatus Muscle-Tendon-Bone Unit
Area of Honors:
Biomedical Engineering
Keywords:
finite element model
shoulder tear
sensitivity analysis
tendinopathy treatments
dry needling
focused ultrasound
rat
supraspinatus muscle-tendon-bone unit
File:
Login to Download
Thesis Supervisors:
Meghan Vidt, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Julianna Simon, Faculty Reader

96. Assessing the Influence of Biomechanical Factors in Injury Exposure for American Sign Language (ASL) Users

restricted_to_institution
Restricted (Penn State Only)
Author:
Demalis, Emily
Title:
Assessing the Influence of Biomechanical Factors in Injury Exposure for American Sign Language (ASL) Users
Area of Honors:
Biomedical Engineering
Keywords:
American Sign Language
Motion capture
Biomechanical assessments
Ballistic signing
Work envelope
Hand and wrist deviations
Factor analysis
File:
Login to Download
Thesis Supervisors:
Meghan Vidt, Thesis Supervisor
Jian Yang, Thesis Honors Advisor
Justin Lee Brown, Faculty Reader

98. A Study of the Effect of an Elevated Beat Rate in the Left Side of the 12cc Penn State Pediatric Total Artificial Heart

restricted_to_institution
Restricted (Penn State Only)
Author:
Raich, Emma
Title:
A Study of the Effect of an Elevated Beat Rate in the Left Side of the 12cc Penn State Pediatric Total Artificial Heart
Area of Honors:
Biomedical Engineering
Keywords:
total artificial heart
pediatric
mechanical circulatory support devices
particle image velocimetry
thrombosis
elevated beat rate
wall shear rate
cardiovascular fluid dynamics
File:
Login to Download
Thesis Supervisors:
Keefe B Manning, Thesis Supervisor
Justin Lee Brown, Thesis Honors Advisor
William Joseph Weiss, Faculty Reader