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Start Over Thesis Supervisor Dr. William O Hancock

1. THE ROLE OF CYTOSKELETON PROTEINS IN THE DETERMINATION OF NEURONAL POLARITY

open_access
Open Access
Author:
Han, Anna Q.
Title:
THE ROLE OF CYTOSKELETON PROTEINS IN THE DETERMINATION OF NEURONAL POLARITY
Area of Honors:
Bioengineering
Keywords:
cytoskeleton proteins
cofilin
slingshot
LIM kinase
neuronal polarity
hippocampal neurons
File:
Download Han.Anna.Spring_2010_Thesis.pdf
Thesis Supervisors:
Dr. Gong Chen, Thesis Supervisor
Dr. Gong Chen, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

2. THE EFFECTS OF THE TUMOR MICROENVIRONMENT ON ENDOTHELIAL CELLULAR ADHESION MOLECULE EXPRESSION

open_access
Open Access
Author:
Goodrich, Christopher James
Title:
THE EFFECTS OF THE TUMOR MICROENVIRONMENT ON ENDOTHELIAL CELLULAR ADHESION MOLECULE EXPRESSION
Area of Honors:
Bioengineering
Keywords:
cancer
metastasis
adhesion
ICAM-1
File:
Download Thesis_Reviewed_Final_-_Christopher_Goodrich.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

4. A Computational Study of Airflow in a Standardized Human Nasal Cavity: Implications Regarding Olfaction

open_access
Open Access
Author:
Shenk, Elizabeth Marie
Title:
A Computational Study of Airflow in a Standardized Human Nasal Cavity: Implications Regarding Olfaction
Area of Honors:
Bioengineering
Keywords:
human olfaction
nasal airflow
standardized human nasal cavity
CFD analysis
File:
Download Shenk_Thesis.pdf
Thesis Supervisors:
Brent A Craven, Thesis Supervisor
Brent A Craven, Thesis Supervisor
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Faculty Reader

5. The Effects of Combination Zoledronate and Docetaxel Therapy on Breast Cancer Colonization of Three-Dimensional Osteoblastic Tissue

open_access
Open Access
Author:
Miller, Genevieve Nicole
Title:
The Effects of Combination Zoledronate and Docetaxel Therapy on Breast Cancer Colonization of Three-Dimensional Osteoblastic Tissue
Area of Honors:
Bioengineering
Keywords:
breast cancer
bone metastasis
bisphosphonate
File:
Download Miller_Genevieve_Honors_Thesis_2010.pdf
Thesis Supervisors:
Erwin A Vogler, Thesis Supervisor
Erwin A Vogler, Thesis Supervisor
Andrea Marie Mastro, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

7. PARTICLE SORTING WITH SURFACE ACOUSTIC WAVES (SAW) FOR A FULLY INTEGRATED MICROFLUIDIC FLOW CYTOMETER

open_access
Open Access
Author:
Pisupati, Karthik
Title:
PARTICLE SORTING WITH SURFACE ACOUSTIC WAVES (SAW) FOR A FULLY INTEGRATED MICROFLUIDIC FLOW CYTOMETER
Area of Honors:
Bioengineering
Keywords:
microfluidic
surface acoustic wave
sorting
File:
Download karthikpisupati_thesis.pdf
Thesis Supervisors:
Jun Huang, Thesis Supervisor
Jun Huang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Siyang Zheng, Faculty Reader

8. Improving Carbon Fiber Microelectrode Performance for Measuring Serotonin by Voltammetry

open_access
Open Access
Author:
Sawarynski, Lauren Elizabeth
Title:
Improving Carbon Fiber Microelectrode Performance for Measuring Serotonin by Voltammetry
Area of Honors:
Bioengineering
Keywords:
serotonin
carbon fiber microelectrodes
voltammetry
File:
Download LSawarynski_FinalThesis.pdf
Thesis Supervisors:
Dr. Anne Milasincic Andrews, Ph D, Thesis Supervisor
Dr. Anne Milasincic Andrews, Ph D, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

10. AORTIC OUTLET EXTENSION IN THE 12CC PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE

open_access
Open Access
Author:
Fickes, Michael Glenn
Title:
AORTIC OUTLET EXTENSION IN THE 12CC PENN STATE PEDIATRIC VENTRICULAR ASSIST DEVICE
Area of Honors:
Bioengineering
Keywords:
outlet valve extension
blockage
PVAD
File:
Download Michael_Fickes_Honors_Thesis_Schreyers.pdf
Thesis Supervisors:
Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Steven Deutsch, Faculty Reader

11. The Challenges of Implanting the Penn State Pediatric Ventricular Assist Device: Study of the Ascending Aorta Anastomotic Flow

open_access
Open Access
Author:
Perone, Michael Vincent
Title:
The Challenges of Implanting the Penn State Pediatric Ventricular Assist Device: Study of the Ascending Aorta Anastomotic Flow
Area of Honors:
Bioengineering
Keywords:
Penn State PVAD
anastomosis
File:
Download Perone_-_Honors_Thesis.pdf
Thesis Supervisors:
Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Steven Deutsch, Faculty Reader

12. THE EFFECTS OF MULTIPLE KINESIN MOTORS ON CARGO TRANSPORT VELOCITY

open_access
Open Access
Author:
Bizzaro, Nicholas Robert
Title:
THE EFFECTS OF MULTIPLE KINESIN MOTORS ON CARGO TRANSPORT VELOCITY
Area of Honors:
Bioengineering
Keywords:
motor proteins
kinesin
cellular transport
File:
Download Schreyer_Honors_College_Thesis_-_Nicholas_Bizzaro.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader
Margaret June Slattery, Faculty Reader

13. THE CHARACTERIZATION OF A MICROCHANNEL DEVICE USING LASER BASED MICRO-PIV

open_access
Open Access
Author:
Wang , Sicong
Title:
THE CHARACTERIZATION OF A MICROCHANNEL DEVICE USING LASER BASED MICRO-PIV
Area of Honors:
Bioengineering
Keywords:
microchannel
microfluidics
micro-PIV
soft lithography
murray law
circulating tumor cell
velocity profile
volumetric flow rate
pulastive flow
PDMS
File:
Download THECHARACTERIZATION_OF_MICROCHANNEL_DEVICE_USING_LASER_BASEDMICROPIV.pdf
Thesis Supervisors:
Siyang Zheng, Thesis Supervisor
Siyang Zheng, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

14. DEVELOPMENT AND CHARACTERIZATION OF EXTRACELLULAR AND INTRACELLULAR TARGETS IN TUMOR-INDUCED ENDOTHELIAL JUNCTION REGULATIONS

open_access
Open Access
Author:
Yunkunis, Tara Marie
Title:
DEVELOPMENT AND CHARACTERIZATION OF EXTRACELLULAR AND INTRACELLULAR TARGETS IN TUMOR-INDUCED ENDOTHELIAL JUNCTION REGULATIONS
Area of Honors:
Bioengineering
Keywords:
signaling
VE-cadherin
calcium
File:
Download Yunkunis_Thesis_SHC_FINAL.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

15. Modeling the Roll-Slip Nonlinear Dynamics of the Knee

open_access
Open Access
Author:
Gagliardi, Virginia Marie
Title:
Modeling the Roll-Slip Nonlinear Dynamics of the Knee
Area of Honors:
Bioengineering
Keywords:
knee
knee joint
prosthetics
dynamics of the knee
roll-slide
roll-slip
oscillator
File:
Download Gagliardi_Thesis_Spring_2010.pdf
Thesis Supervisors:
Joseph Paul Cusumano, Thesis Supervisor
Joseph Paul Cusumano, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Margaret June Slattery, Faculty Reader

17. Feasibility Studies for Optical Trap Detection of Single Molecule Adhesion and Force Generation

open_access
Open Access
Author:
Bernick, David J
Title:
Feasibility Studies for Optical Trap Detection of Single Molecule Adhesion and Force Generation
Area of Honors:
Bioengineering
Keywords:
optical trap
laser tweezers
integrin ligand binding
bead
avidin
biotin
microscopy
File:
Download Final_Thesis_Bernick_David_Optical_Trap.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. Keefe B Manning, Faculty Reader
Dr. William O Hancock, Faculty Reader

19. Finite Element Analysis of Microfabricated Poly(Glycerol Sebacate) Scaffolds for use in Heart Valve Tissue Engineering

open_access
Open Access
Author:
Chowdhury, Surjyanil
Title:
Finite Element Analysis of Microfabricated Poly(Glycerol Sebacate) Scaffolds for use in Heart Valve Tissue Engineering
Area of Honors:
Bioengineering
Keywords:
Chowdhury
finite element
COMSOL
heart valve
tissue engineering
poly glycerol sebacate
PGS
microfabricate
scaffold
mesh
File:
Download honors_thesis_final_draft.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. Keefe B Manning, Faculty Reader

20. The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs)

open_access
Open Access
Author:
Sheldrake, Anne E
Title:
The effect of substrate stiffness on fibrillin expression by mouse embryonic fibroblasts (MEFs)
Area of Honors:
Bioengineering
Keywords:
MEFs
tissue engineering
cardiac
acrylamide
bisacrylamide
heart
fibrillin
scar tissue
File:
Download sheldrake_anne_effect_of_susbstrate_stiffness.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

24. Encapsulation of Docetaxel in Calcium Phosphosilicate Nanoparticles and the Effects of Bioconjugation

open_access
Open Access
Author:
Hughes, Kelly E
Title:
Encapsulation of Docetaxel in Calcium Phosphosilicate Nanoparticles and the Effects of Bioconjugation
Area of Honors:
Bioengineering
Keywords:
nanoparticles
breast cancer
cancer
calcium phosphate
File:
Download Hughes_Honors_Thesis.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
James Hansell Adair, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

26. An In Vitro Investigation of the Effect of Shear on von Willebrand Factor Proteolysis

open_access
Open Access
Author:
Burke, Shannon Leigh
Title:
An In Vitro Investigation of the Effect of Shear on von Willebrand Factor Proteolysis
Area of Honors:
Bioengineering
Keywords:
von Willebrand factor
vWF
ventricular assist device
VAD
proteolysis
heart failure
cardiovascular disease
File:
Download Shannon_Burke_-_Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader
Margaret June Slattery, Faculty Reader

28. Fluid Dynamic Studies of a Porcine Aortic Valve in Preparation for Future Living Tissue Valve Studies

open_access
Open Access
Author:
Schmiech, Kathryn Victoria
Title:
Fluid Dynamic Studies of a Porcine Aortic Valve in Preparation for Future Living Tissue Valve Studies
Area of Honors:
Bioengineering
Keywords:
aortic valve
fluid dynamics
porcine valve
particle image velocimetry
File:
Download KSchmiechFinalThesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

29. Investigating the Mechanics of Cancer Cell Membranes Using Microfluidics

open_access
Open Access
Author:
Ramadi, Khalil Basil
Title:
Investigating the Mechanics of Cancer Cell Membranes Using Microfluidics
Area of Honors:
Bioengineering
Keywords:
Cancer
CTC
Isolation
Characterization
Tumor
Membrane
Mechanics
Cell
Expansion
Osmosis
Microfluidics
Viscoelasticity
File:
Download Thesis_Final_final_v2.pdf
Thesis Supervisors:
Siyang Zheng, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

30. Effects of Synonymous, Consecutive, Repetitive Codons on Bacterial Translation Elongation Rates

open_access
Open Access
Author:
Heasley, Victoria Lynn
Title:
Effects of Synonymous, Consecutive, Repetitive Codons on Bacterial Translation Elongation Rates
Area of Honors:
Bioengineering
Keywords:
repetitive codon sequences elongation
affects on translation elongation rates
synthetic biology
genetic engineering
File:
Download Heasley_Victoria__Effects_of_Repetitive_Codons_on_Elongation.pdf
Thesis Supervisors:
Howard M Salis, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

31. The Effect of Blood on Circulating Tumor Cells' Expression of Epithelial and Mesenchymal Cell Markers

open_access
Open Access
Author:
Clabbers, Andrea Laurie
Title:
The Effect of Blood on Circulating Tumor Cells' Expression of Epithelial and Mesenchymal Cell Markers
Area of Honors:
Bioengineering
Keywords:
Circulating Tumor Cells
EpCAM
Epithelial to Mesenchymal Transition
File:
Download Andrea_Clabbers_Thesis_Final.pdf
Thesis Supervisors:
Siyang Zheng, Thesis Supervisor
Sheereen Majd, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

32. The Effect of Consumption of the Probiotic Bifidobacterium Animalis Subspecies Lactis (BB-12) on Function and Phenotype of Natural Killer Cells

open_access
Open Access
Author:
Krisher, Sarah Yelena
Title:
The Effect of Consumption of the Probiotic Bifidobacterium Animalis Subspecies Lactis (BB-12) on Function and Phenotype of Natural Killer Cells
Area of Honors:
Bioengineering
Keywords:
probiotics
BB-12
natural killer cells
File:
Download Sarah_Krisher__Final_Thesis_Submission.pdf
Thesis Supervisors:
Connie Jo Rogers, Thesis Supervisor
Sheereen Majd, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

33. An Experimental Setup to Test the Effects of Shear Stress on von Willebrand Factor

open_access
Open Access
Author:
Corsetti, Monica Claire
Title:
An Experimental Setup to Test the Effects of Shear Stress on von Willebrand Factor
Area of Honors:
Bioengineering
Keywords:
von Willebrand Factor
vWF
Optical Trap
Optical Tweezers
Shear Stress
Acquired von Willebrand Syndrome
ADAMTS-13
File:
Download Thesis_Monica_Corsetti.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Peter J Butler, Faculty Reader
Dr. William O Hancock, Faculty Reader
Dr. Keefe B Manning, Thesis Honors Advisor

34. Nanofiber Control of Focal Adhesion Dynamics and Cell Migration for Regenerative Medicine

open_access
Open Access
Author:
Riley, Thomas Roberts
Title:
Nanofiber Control of Focal Adhesion Dynamics and Cell Migration for Regenerative Medicine
Area of Honors:
Bioengineering
Keywords:
Matlab
Image Processing
Focal Adhesion
Cell Migration
Nanofiber
Tissue Engineering
Regenerative Medicine
FAITS
File:
Download RileyThesisFinalDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

35. In Vitro and Computational Analysis of the Fluid Mechanics Promoting Thrombus Formation in a Backward-facing Step Flow Domain

open_access
Open Access
Author:
Witmer, Kory P
Title:
In Vitro and Computational Analysis of the Fluid Mechanics Promoting Thrombus Formation in a Backward-facing Step Flow Domain
Area of Honors:
Bioengineering
Keywords:
thrombosis
fluid mechanics
computational fluid dynamics
cardiovascular devices
magnetic resonance imaging
File:
Download Schreyer_FinalThesis_Witmer_Kory.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

36. Histological Analysis of in vitro Thrombus Formation in a Backward Facing Step Flow Domain Using Carstairs' Stain

open_access
Open Access
Author:
Kinney, Joanna E
Title:
Histological Analysis of in vitro Thrombus Formation in a Backward Facing Step Flow Domain Using Carstairs' Stain
Area of Honors:
Bioengineering
Keywords:
thrombosis
histology
bioengineering
heart
blood
File:
Download Kinney_Joanna_Thesis_Final.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Peter J Butler, Faculty Reader

37. A Fluid Dynamic Study of the Effect of Hematocrit in the 12 cc Penn State Pediatric Ventricular Assist Device

open_access
Open Access
Author:
Silver, Jeremy Michael
Title:
A Fluid Dynamic Study of the Effect of Hematocrit in the 12 cc Penn State Pediatric Ventricular Assist Device
Area of Honors:
Bioengineering
Keywords:
ventricular assist device
pediatric
cardiovascular device
hematocrit
thrombosis
particle image velocimetry
piv
VAD
PVAD
File:
Download Silver_SHC_Thesis_FINAL.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader
Peter J Butler, Faculty Reader

38. Targeted Sequencing Of Chromosome 9 Genes Associated With Papillary Type 1 Renal Cell Carcinoma

open_access
Open Access
Author:
Belsky, Michael Alan
Title:
Targeted Sequencing Of Chromosome 9 Genes Associated With Papillary Type 1 Renal Cell Carcinoma
Area of Honors:
Biomedical Engineering
Keywords:
Cancer
next generation sequencing
renal cell carcinoma
targeted sequencing
papillary type 1
File:
Download Belsky_Thesis_Final.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Thesis Honors Advisor
Dr. William A La Framboise, Faculty Reader

39. Single-molecule microscopy step detection algorithms: kinesin motor proteins and the cellulose synthesis complex

open_access
Open Access
Author:
Deffenbaugh, Nathan C
Title:
Single-molecule microscopy step detection algorithms: kinesin motor proteins and the cellulose synthesis complex
Area of Honors:
Bioengineering
Keywords:
kinesin
motor proteins
step detection
single-molecule
cellulose synthesis complex
hidden Markov model
File:
Download DeffenbaughNathan_SHCThesis_May2015.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Peter J Butler, Faculty Reader
Dr. Justin Lee Brown, Faculty Reader
Dr. William O Hancock, Thesis Honors Advisor

41. A Study in the Design of an Accelerated Wear Tester that is Compatible with a Particle Image Velocimetry and High Speed Camera Setup

open_access
Open Access
Author:
Brown, Edward Alexander
Title:
A Study in the Design of an Accelerated Wear Tester that is Compatible with a Particle Image Velocimetry and High Speed Camera Setup
Area of Honors:
Bioengineering
Keywords:
Accelerated Wear Tester
Particle Image Velocimetry
AWT
PIV
Heart Valve
Artificial Heart Valve
Fluid Dynamics
File:
Download Edward_A_Brown_Honors_Thesis.pdf
Thesis Supervisors:
Dr. Keefe B Manning, Thesis Supervisor
Dr. Keefe B Manning, Thesis Honors Advisor
Dr. William O Hancock, Faculty Reader

42. Development of A Multi-layered Micro-patterned Electrospun Mesh for Hernia Repair

open_access
Open Access
Author:
Orr, Sara A
Title:
Development of A Multi-layered Micro-patterned Electrospun Mesh for Hernia Repair
Area of Honors:
Bioengineering
Keywords:
electrospin
electrospun
hernia
mesh
File:
Download 1-Orr_Sara_TheDevelopmentofAMultiLayeredMicroPatternedElectrospunMeshforHerniaRepair.pdf
Thesis Supervisors:
Jian Yang, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Yong Wang, Faculty Reader

43. Modeling the Bidirectional Transport of Intracellular Cargos by Oppositely-directed Motor Proteins

open_access
Open Access
Author:
Mentley, Brandon Scott
Title:
Modeling the Bidirectional Transport of Intracellular Cargos by Oppositely-directed Motor Proteins
Area of Honors:
Bioengineering
Keywords:
kinesin
dynein
motor protein
bidirectional transport
matlab
simulation
File:
Download Brandon_Mentley_-_Thesis_Final_Fall15.pdf
Thesis Supervisors:
Dr. William O Hancock, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
John Fricks, Faculty Reader

44. THE EFFECTS OF BIOCONJUGATION OF CALCIUM PHOSPHOSILICATE NANOPARTICLES ON THE DELIVERY TO BREAST CANCER CELLS

open_access
Open Access
Author:
Gonzalez, Virginia Laura
Title:
THE EFFECTS OF BIOCONJUGATION OF CALCIUM PHOSPHOSILICATE NANOPARTICLES ON THE DELIVERY TO BREAST CANCER CELLS
Area of Honors:
Bioengineering
Keywords:
Calcium Phosphosilicate
Nanoparticles
Breast Cancer
Transendothelial Migration
File:
Download Honors_Thesis_VLG.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

45. β-Catenin Signaling Leading to the Maintenance and Differentiation of MC3T3 Cells in Response to Electrospun Nanofibers

open_access
Open Access
Author:
Nagurney, Rebecca Ann
Title:
β-Catenin Signaling Leading to the Maintenance and Differentiation of MC3T3 Cells in Response to Electrospun Nanofibers
Area of Honors:
Bioengineering
Keywords:
Nanofibers
Electrospinning
PMMA
PolyHEMA
Polyvinyl Alcohol
Beta-Catenin
Osteogenesis
File:
Download Nagurney_FinalThesis_BIOE_2016.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

46. Factors Impacting the Efficacy of Cell-mediated Drug Delivery to the Brain via the Blood Brain Barrier

open_access
Open Access
Author:
Selvi, Erhan Yavuz
Title:
Factors Impacting the Efficacy of Cell-mediated Drug Delivery to the Brain via the Blood Brain Barrier
Area of Honors:
Bioengineering
Keywords:
cell-mediated drug delivery
blood brain barrier
VE-cadherin
VCAM-1
ICAM-1
VLA-4
LFA-1
transendothelial migration
File:
Download SCHREYER_THESIS_4.11.16_final.pdf
Thesis Supervisors:
Cheng Dong, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Dr. Justin Lee Brown, Faculty Reader

47. The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells

open_access
Open Access
Author:
Porter, Michael John
Title:
The Investigation of the Uptake of Interleukin-13 Conjugated Nanoparticles into Glioma Cells
Area of Honors:
Biomedical Engineering
Keywords:
Nanoparticle
Nanoparticles
IL-13
Interleukin
Glioma
GBM
Glioblastoma multiforme
conjugated
computational
kinetics
File:
Download Final_Thesis_Porter.pdf
Thesis Supervisors:
Sheereen Majd, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Herbert Herling Lipowsky, Faculty Reader

48. THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS

open_access
Open Access
Author:
Mcculloch, Mary Elizabeth
Title:
THE EFFECT OF NANOFIBER DIAMETERS ON INTEGRIN REGULATED FAK-SRC SIGNALLING AND MIGRATION RATES OF HUMAN MESENCHYMAL STEM CELLS
Area of Honors:
Biomedical Engineering
Keywords:
FAK
SRC
Tissue Engineering
hMSCs
migration
Focal adhesions
File:
Download HonorsFINALThesisDraft.pdf
Thesis Supervisors:
Dr. Justin Lee Brown, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor

49. Comparing Novel Techniques for Measuring the Bending Modulus of Lipid Bilayer Membranes in Erythrocytes

open_access
Open Access
Author:
Frazzette, Nicholas James
Title:
Comparing Novel Techniques for Measuring the Bending Modulus of Lipid Bilayer Membranes in Erythrocytes
Area of Honors:
Bioengineering
Keywords:
mechanobiology
bending modulus
mechanotransduction
lipid bilayers
membrane bending
erythrocytes
TCSPC
fluorescence
File:
Download Frazzette_SHC_Thesis_v4.pdf
Thesis Supervisors:
Peter J Butler, Thesis Supervisor
Dr. William O Hancock, Thesis Honors Advisor
Herbert Herling Lipowsky, Faculty Reader